Associate Professor of Surgery, University of Illinois College of Medicine
General Surgery
Dr. Mark J. Holterman, MD
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Mark Holterman works in the field of General Surgery. He studied medicine at University of Virginia School of Medicine. He received 4 awards: "America's Top Doctors", "Chicago Mag - Children's Health", "Chicago Magazine: Top Doctors" and "Fellow (FACS)". Mark Holterman has written publications. He has 23 publications published with PubMed. The lastest paper is: 'Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory Cytokine: Implications for Immune Therapy.'
Publications
- Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory Cytokine: Implications for Immune Therapy.
- Nonalcoholic fatty liver disease in severely obese adolescent and adult patients.
- Transcriptome Analysis of Epigenetically Modulated Genome Indicates Signature Genes in Manifestation of Type 1 Diabetes and Its Prevention in NOD Mice.
- Pediatric obesity.
- Selective destruction of mouse islet beta cells by human T lymphocytes in a newly-established humanized type 1 diabetic model.
- Dendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1 diabetes.
- New type of human blood stem cell: a double-edged sword for the treatment of type 1 diabetes.
- A prospective trial for laparoscopic adjustable gastric banding in morbidly obese adolescents: an interim report of weight loss, metabolic and quality of life outcomes.
- Persistent hypoglycemia in a child with a gastrocolic Fistula--an unexpected presentation of leucine-sensitive hypoglycemia.
- Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice.
- Simultaneous costal cartilage-sparing modified Ravitch procedure and latissimus dorsi transfer for Chest wall deformity repair in Poland's syndrome.
- Preferential costimulation by CD80 results in IL-10-dependent TGF-beta1(+) -adaptive regulatory T cell generation.
- Enhanced engagement of CTLA-4 induces antigen-specific CD4+CD25+Foxp3+ and CD4+CD25- TGF-beta 1+ adaptive regulatory T cells.
- Laparoscopic adjustable gastric banding for the treatment of adolescent morbid obesity in the United States: a safe alternative to gastric bypass.
- Electron beam CT scan is a valuable and safe imaging tool for the pediatric surgical patient.
- Targeted CTLA-4 engagement induces CD4+CD25+CTLA-4high T regulatory cells with target (allo)antigen specificity.
- Adenovirus serotype 3 utilizes CD80 (B7.1) and CD86 (B7.2) as cellular attachment receptors.
- Costimulatory molecule immune enhancement in a plasmid vaccine model is regulated in part through the Ig constant-like domain of CD80/86.
- Selective induction of dendritic cells using granulocyte macrophage-colony stimulating factor, but not fms-like tyrosine kinase receptor 3-ligand, activates thyroglobu...
- Absence of IL-4, and not suppression of the Th2 response, prevents development of experimental autoimmune Graves' disease.
- Per-6-substituted beta-cyclodextrin libraries inhibit formation of beta-amyloid-peptide (A beta)-derived, soluble oligomers.
- CD80 (B7-1) and CD86 (B7-2) are functionally equivalent in the initiation and maintenance of CD4+ T-cell proliferation after activation with suboptimal doses of PHA.
Schools
University Of Virginia School Of Medicine
University Of Virginia Hospital
Children39s Hospital and Medical C
Childrens Hospital amp Regional Medical Center
Yale University
Clnical Research Institute Of Montreal
University Of VirginiaPhD
Procedures Preformed
- Adhesiolysis
- Adrenalectomy
- Anal Repair
- Anti-Reflux Surgery
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Conditions Treated
- Appendicitis
- Chest Wall Deformity
- Esophageal Fistula
- Gastrointestinal Diseases
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Doctors Specialties
- Pediatric Surgery
- General Surgery
Accepted Insurances
Awards
- America's Top Doctors
- Chicago Mag - Children's Health
- Chicago Magazine: Top Doctors
- Fellow (FACS)
Education
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University of Virginia -
University of Virginia School of Medicine
Hospital
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University of Illinois Hospital & Health Sciences System -
Carle Foundation Hospital
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