Professor, Orthopedics, Mayo Medical School
Orthopaedic Surgery
Dr. Mark E. Bolander, MD
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Doctor Mark E. Bolander, MD is an expert in the field of Orthopaedic Surgery. He attended Loyola University Chicago Stritch School of Medicine. Mark Bolander is a published doctor. He has 101 publications published. The most current publication "Gene digging. A method for obtaining species-specific sequence based on conserved segments of nucleotides in open reading frames."
Publications
- Osteoblastic and osteolytic human osteosarcomas can be studied with a new xenograft mouse model producing spontaneous metastases.
- Cellular uptake of gold nanoparticles directly cross-linked with carrier peptides by osteosarcoma cells.
- Evidence of genetic locus heterogeneity for familial bicuspid aortic valve.
- Engineering a noncarrier to a highly efficient carrier peptide for noncovalently delivering biologically active proteins into human cells.
- TASR-1 regulates alternative splicing of collagen genes in chondrogenic cells.
- Elevated expressions of osteopontin and tenascin C in ascending aortic aneurysms are associated with trileaflet aortic valves as compared with bicuspid aortic valves.
- Follow-up study of long-term survivors of osteosarcoma in the prechemotherapy era.
- High WT1 expression is associated with very poor survival of patients with osteogenic sarcoma metastasis.
- Bicuspid aortic valve and ascending aortic aneurysm are not associated with germline or somatic homeobox NKX2-5 gene polymorphism in 19 patients.
- Providing "just-in-time" medical genomics information for patient care.
- Oligonucleotide decoy mimicking alphaA-crystallin-binding protein 1 binding site on mouse Col2a1 enhancer stimulates transcription from the adjacent Col2a1 promoter in...
- Continuous parathyroid hormone induces cortical porosity in the rat: effects on bone turnover and mechanical properties.
- Evaluation of different conditions for ligating dumbbell-shaped oligonucleotides.
- Barriers and solutions to osteoporosis care in patients with a hip fracture.
- Cis-acting intronic elements that regulate cartilage-specific alternative splicing of the type II collagen (Col2) pre-mRNA lie at or near splice site junction sequence...
- Total joint arthroplasty in human immunodeficiency virus-positive patients: an alarming rate of early failure.
- Primer on medical genomics. Part III: Microarray experiments and data analysis.
- The spatiotemporal expression of TGF-beta1 and its receptors during periosteal chondrogenesis in vitro.
- Alumina-on-alumina total hip arthroplasty: a minimum 18.5-year follow-up study.
- Calcium signaling is required for ultrasound-stimulated aggrecan synthesis by rat chondrocytes.
- Further characterization of human fetal osteoblastic hFOB 1.19 and hFOB/ER alpha cells: bone formation in vivo and karyotype analysis using multicolor fluorescent in s...
- Identification of twenty-two candidate markers for human osteogenic sarcoma.
- Fate of ultrahigh molecular weight polyethylene (UHMW-PE) wear debris in patients with hip implants.
- A method for accurate detection of translocation junctions in Ewing family of tumors.
- The use of low-intensity ultrasound to accelerate the healing of fractures.
- Differential mRNA fingerprinting by preferential amplification of coding sequences.
- Identification of differentially expressed genes by mutually subtracted RNA fingerprinting.
- Ciprofloxacin inhibition of experimental fracture healing.
- Initial evidence for the involvement of bone morphogenetic protein-2 early during periosteal chondrogenesis.
- Inhibition of endochondral ossification during fracture repair in experimental hypothyroid rats.
- High temperature cDNA synthesis by AMV reverse transcriptase improves the specificity of PCR.
- Repeat cDNA synthesis and RT-PCR with the same source of RNA.
- Low-intensity ultrasound stimulates proteoglycan synthesis in rat chondrocytes by increasing aggrecan gene expression.
- Micro-CT imaging of structure-to-function relationship of bone microstructure and associated vascular involvement.
- Gene digging. A method for obtaining species-specific sequence based on conserved segments of nucleotides in open reading frames.
- Selective differential fingerprinting. A method for identifying differentially expressed genes in a family between two samples.
- Rapid acquisition of unknown DNA sequence adjacent to a known segment by multiplex restriction site PCR.
- Artificial cavitation nuclei significantly enhance acoustically induced cell transfection.
- Oligoclonal T-cell proliferation and interferon-gamma production in periprosthetic inflammation.
- PIG-B: a homemade monophasic cocktail for the extraction of RNA.
- Histologic and biochemical differences between osteolytic and nonosteolytic membranes around femoral components of an uncemented total hip arthroplasty.
- Evidence for the upregulation of osteogenic protein-1 mRNA expression in musculoskeletal neoplasms.
- Direct sequencing of unpurified PCR-amplified DNA by semi-exponential cycle sequencing (SECS).
- An effective method of completely removing contaminating genomic DNA from an RNA sample to be used for PCR.
- A method for determination of stiffness of collagen molecules.
- Osteoblasts express types I and II activin receptors during early intramembranous and endochondral bone formation.
- Identification of a dual leucine zipper kinase involved in rat fracture repair.
- Exposure to low-intensity ultrasound increases aggrecan gene expression in a rat femur fracture model.
- Ultrasound-mediated transfection of mammalian cells.
- A differential scanning calorimetry study of retrieved orthopedic implants made of ultrahigh molecular weight polyethylene.
- Improved design of riboprobes from pBluescript and related vectors for in situ hybridization.
- Restriction-site PCR: a direct method of unknown sequence retrieval adjacent to a known locus by using universal primers.
- Low intensity ultrasound treatment increases strength in a rat femoral fracture model.
- Stimulatory effect of potassium glutamate in PCR.
- Induction of growth plate cartilage ossification by basic fibroblast growth factor.
- Type X collagen in fracture callus and the effects of experimental diabetes.
- Deletion mutation can be an unsuspected gel artifact.
- The "looped oligo" method for generating reference molecules for quantitative PCR.
- Hip arthroplasty in hemophilic arthropathy.
- Telomeres, telomerase, and cancer.
- Semi exponential cycle sequencing.
- Gene identification by arrested primer extension.
- Estrogen receptor mRNA is expressed in vivo in rat calvarial periosteum.
- Transforming growth factor-beta 1 and fibroblast growth factors in rat growth plate.
- Enhancement of bone ingrowth by the use of bone matrix as a biologic cement.
- The use of demineralized bone matrix in the repair of segmental defects. Augmentation with extracted matrix proteins and a comparison with autologous grafts.
- Growth factors and their role in wound and fracture healing.
- An established rat cell line expressing chondrocyte properties.
- Osteonectin mRNA: distribution in normal and transformed cells.
- Osteonectin cDNA sequence reveals potential binding regions for calcium and hydroxyapatite and shows homologies with both a basement membrane protein (SPARC) and a ser...
- Defects of early fracture-healing in experimental diabetes.
- Estrogen receptor mRNA expression in callus during fracture healing in the rat.
- Isolation and analysis of ribonucleic acids from skeletal tissues.
- Monoclonal antibodies against osteonectin show conservation of epitopes across species.
- Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur.
- Regulation of the collagen II gene in vitro and in transgenic mice.
- Acidic fibroblast growth factor (aFGF) injection stimulates cartilage enlargement and inhibits cartilage gene expression in rat fracture healing.
- Transforming growth factor-beta in the regulation of fracture repair.
- Role of transforming growth factor-beta in fracture repair.
- Detection and measurement of simulated early rheumatoid lesions of the hand using digital subtraction radiography.
- The use of polymerase chain reaction generated nucleotide sequences as probes for hybridization.
- Role of growth factors in fracture healing.
- Transforming growth factor beta 1 stimulates type II collagen expression in cultured periosteum-derived cells.
- Impaired bone activity in aged rats: alterations at the cellular and molecular levels.
- Genetic expression of extracellular matrix proteins correlates with histologic changes during fracture repair.
- Regulation of fracture repair by growth factors.
- Secular trends in hip fracture incidence and recurrence.
- Use of tumor dynamics to clarify the observed variability among biochemical recurrence nomograms for prostate cancer.
- An integrated approach to assess structure-to-function relationships in the skeleton.
- Intragenic codon bias in a set of mouse and human genes.
- Development of a cellular model to study alternative splicing of type II collagen gene.
- The human homolog of yeast SEP1 is a novel candidate tumor suppressor gene in osteogenic sarcoma.
- Determination of the complete cDNA sequence of rat type II collagen and evaluation of distinct expression patterns of types IIA and IIB procollagen mRNAs during fractu...
- Two-dimensional gel electrophoresis of synovial fluid: method for detecting candidate protein markers for osteoarthritis.
- Statin stimulates bone morphogenetic protein-2, aggrecan, and type 2 collagen gene expression and proteoglycan synthesis in rat chondrocytes.
- Use of physical forces in bone healing.
- Informed use of proteolytic inhibitors in biomarker discovery.
- Identification of estrogen-regulated genes during fracture healing, using DNA microarray.
- Expression of a novel alternatively spliced UCP-2 transcript in osteogenic sarcoma.
- The use of microorganisms for the formation of metal nanoparticles and their application.
Schools
Loyola University Of ChicagoStritch School Of Medicine
University Of Mi Hosps and Health Ctrs
Northwestern University
Conditions Treated
- Back Pain
Doctors Specialties
- Orthopedic Surgery
- Orthopaedic Surgery
Accepted Insurances
Education
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National Institutes of Health Clinical Center -
University of Virginia -
University of Michigan Hospitals and Health Centers -
Loyola University Chicago Stritch School of Medicine
Hospital
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Mayo Clinic - Rochester, Minnesota
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