Professor, Pediatrics and Cellular and Molecular Physiology, Yale University School of Medicine
Pediatric Pulmonology
Dr. Marie E. Egan, MD
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Marie E. Egan, MD works in the field of Pediatric Pulmonology. She graduated from Icahn School of Medicine at Mount Sinai. Icahn School of Medicine at Mount Sinai is ranked 20/62 in Research/PrimaryCare. Marie Egan is a published MD as well. She has 41 publications published. The latest was: CFTR is a conductance regulator as well as a chloride channel.
Publications
- Restoration of cytoskeletal and membrane tethering defects but not defects in membrane trafficking in the intestinal brush border of mice lacking both myosin Ia and my...
- Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR.
- Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium.
- Association between serum 25-hydroxyvitamin D level and pulmonary exacerbations in Cystic fibrosis.
- Modified Poly(lactic-co-glycolic Acid) Nanoparticles for Enhanced Cellular Uptake and Gene Editing in the Lung.
- Reduced Caveolin-1 Promotes Hyperinflammation due to Abnormal Heme Oxygenase-1 Localization in Lipopolysaccharide-Challenged Macrophages with Dysfunctional Cystic Fibr...
- Baby bottle steam sterilizers disinfect home nebulizers inoculated with bacterial respiratory pathogens.
- Surface modified poly(beta amino ester)-containing nanoparticles for plasmid DNA delivery.
- Long term effects of denufosol tetrasodium in patients with Cystic fibrosis.
- Myosin Ia is required for CFTR brush border membrane trafficking and ion transport in the mouse small intestine.
- Inhaled hypertonic saline in infants and children younger than 6 years with Cystic fibrosis: the ISIS randomized controlled trial.
- Calcium Modulated Chloride Pathways Contribute to Chloride Flux in Murine CF-Affected Macrophages.
- Abnormal Trafficking and Degradation of TLR4 Underlie the Elevated Inflammatory Response in Cystic Fibrosis.
- Mouse Cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct.
- Partial correction of Cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin.
- Pulmonary squamous cell carcinoma associated with repaired congenital tracheoesophageal fistula and esophageal atresia.
- Macrophages directly contribute to the exaggerated inflammatory response in Cystic fibrosis transmembrane conductance regulator-/- mice.
- Automatic time-motion study of a multistep preoperative process.
- Rectal potential difference and the functional expression of CFTR in the gastrointestinal epithelia in Cystic fibrosis mouse models.
- DeltaF508 mutation results in impaired gastric acid secretion.
- Engraftment of donor-derived epithelial cells in multiple organs following bone marrow transplantation into newborn mice.
- CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney.
- Assessment of Cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation.
- Curcumin, a major constituent of turmeric, corrects Cystic fibrosis defects.
- Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in Cystic fibrosis epithelial cells.
- CFTR-associated ATP transport and release.
- Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates Cystic fibrosis lung hyper-inflammation.
- Pseudomonas aeruginosa chronic colonization in Cystic fibrosis patients.
- CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP.
- CFTR is a conductance regulator as well as a chloride channel.
- Assays of dynamics, mechanisms, and regulation of ATP transport and release: implications for study of ABC transporter function.
- Chloride channel and chloride conductance regulator domains of CFTR, the Cystic fibrosis transmembrane conductance regulator.
- Modulation of ion transport in cultured rabbit tracheal epithelium by lipoxygenase metabolites.
- In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in Cystic fibrosis epithelial cells containing delta F508-CFTR.
- Differential expression of ORCC and CFTR induced by low temperature in CF airway epithelial cells.
- Continuous detection of extracellular ATP on living cells by using atomic force microscopy.
- Effects of the serine/threonine kinase SGK1 on the epithelial Na(+) channel (ENaC) and CFTR: implications for Cystic fibrosis.
- A functional CFTR-NBF1 is required for ROMK2-CFTR interaction.
- Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter c...
- Identification of the Cystic fibrosis transmembrane conductance regulator domains that are important for interactions with ROMK2.
Schools
Mount Sinai School of Medicine
Conditions Treated
- Cystic Fibrosis
- Pulmonary Hypertension
Doctors Specialties
- Pediatric Pulmonology
Accepted Insurances
Education
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Johns Hopkins University -
Icahn School of Medicine at Mount Sinai
Hospital
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Greenwich Hospital -
Yale-New Haven Hospital
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