Physician

Oncology

Luba Dumenco is an expert in the field of Oncology. Luba L. Dumenco, MD is a published doctor and has 28 publications published. The lastest was: 'Determinants of O6-alkylguanine-DNA alkyltransferase activity in human colon cancer.'

Publications

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• Playing in the "Gutter": Cultivating Creativity in Medical Education and Practice.
• Introducing technology into medical education: Two pilot studies.
• Curriculum innovation at the Warren Alpert Medical School of Brown University.
• Health disparity curriculum at the warren alpert medical school of brown university.
• Determinants of O6-alkylguanine-DNA alkyltransferase activity in human colon cancer.
• The results of diagnostic studies for thrombophilia in a large group of patients with a personal or family history of thrombosis.
• Analysis of the tumorigenicity of the X gene of hepatitis B virus in a nontransformed hepatocyte cell line and the effects of cotransfection with a murine p53 mutant e...
• Human CD34+ hematopoietic progenitors have low, cytokine-unresponsive O6-alkylguanine-DNA alkyltransferase and are sensitive to O6-benzylguanine plus BCNU.
• Specificity of bischloroethylnitrosourea-induced mutation in a Chinese hamster ovary cell line transformed to express human O6-alkylguanine-DNA alkyltransferase.
• The prevention of thymic lymphomas in transgenic mice by human O6-alkylguanine-DNA alkyltransferase.
• Rapid repair of O6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas.
• The immature thymocyte is protected from N-methylnitrosourea-induced lymphoma by the human MGMT-CD2 transgene.
• Retroviral transduction and expression of the human alkyltransferase cDNA provides nitrosourea resistance to hematopoietic cells.
• Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon.
• Alkyltransferase transgenic mice: probes of chemical carcinogenesis.
• Inhibition of the activation of Hageman factor (factor XII) by platelet factor 4.
• Increase in nitrosourea resistance in mammalian cells by retrovirally mediated gene transfer of bacterial O6-alkylguanine-DNA alkyltransferase.
• High level, regulated expression of the chimeric P-enolpyruvate carboxykinase (GTP)-bacterial O6-alkylguanine-DNA alkyltransferase (ada) gene in transgenic mice.
• Transgenic mice expressing the bacterial O6 alkylguanine-DNA alkyltransferase gene: an animal model to study the role of DNA repair in the carcinogenesis of N-nitroso ...
• Increased drug resistance following retroviral gene transfer of a chimeric P-enolpyruvate carboxykinase (GTP)-bacterial O6-alkylguanine-DNA alkyltransferase gene into ...
• Enhanced repair of O6-methylguanine DNA adducts in the liver of transgenic mice expressing the ada gene.
• Inhibition of the activation of Hageman factor (factor XII) and of platelet aggregation by extracts of Brugia malayi microfilariae.
• Fetal liver hematopoietic stem cells as a target for in utero retroviral gene transfer.
• Comparison of the inactivation of mammalian and bacterial O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine and O6-methylguanine.
• Inhibition of the activation of Hageman factor (factor XII) by extracts of Schistosoma mansoni.
• The Warren Alpert Medical School of Brown University.
• Redesigning the medical science curriculum at the Warren Alpert Medical School of Brown University.

Schools

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• University of Wisconsin Madison

Doctors Specialties

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• Internal Medicine
• Medical Oncology
• Oncology

Accepted Insurances

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