Physician
Oncology
Dr. Louis Matis, MD
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Louis Matis is an expert in the field of Oncology. He studied medicine at Perelman School of Medicine at the University of Pennsylvania. He received awards:"Elected Member". Louis Matis is a published MD. He published 101 publications, including: 'Determinant spreading associated with demyelination in a nonhuman primate model of multiple sclerosis.'
Publications
- Ethanol: an enhancer of major histocompatibility complex antigen expression.
- Interleukin 2 induces antigen-reactive T cell lines to secrete BCGF-I.
- Pharmacology and biological efficacy of a recombinant, humanized, single-chain antibody C5 complement inhibitor in patients undergoing coronary artery bypass graft sur...
- Functional expression and recognition of nonclassical MHC class I T10b is not peptide-dependent.
- The nature of major histocompatibility complex recognition by gamma delta T cells.
- Specificity and selection of gamma-delta receptor-expressing T cells.
- Development of T cell receptor-gamma delta cells. Phenotypic and functional correlations of T cell receptor-gamma delta thymocyte maturation.
- To T or not to T: is it selection?
- Effect of neutralizing antibodies to IL-10 and C5 on the renal damage caused by a pathogenic human anti-dsDNA antibody.
- Inducible costimulator regulates Th2-mediated inflammation, but not Th2 differentiation, in a model of allergic airway disease.
- Tissue-specific expression of messenger RNAs encoding endogenous viral superantigens.
- Repertoire development and ligand specificity of murine TCR gamma delta cells.
- Effective antigen-specific immunotherapy in the marmoset model of multiple sclerosis.
- Primary structure and functional characterization of a soluble, alternatively spliced form of B7-1.
- Role of porcine P-selectin in complement-dependent adhesion of human leukocytes to porcine endothelial cells.
- A role for complement in antibody-mediated inflammation: C5-deficient DBA/1 mice are resistant to collagen-induced arthritis.
- Significant role for Fas in the pathogenesis of autoimmune diabetes.
- Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis.
- Complement inhibition with an anti-C5 monoclonal antibody prevents hyperacute rejection in a xenograft heart transplantation model.
- Ntk: a Csk-related protein-tyrosine kinase expressed in brain and T lymphocytes.
- Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif.
- Two distinct protein isoforms are encoded by ntk, a csk-related tyrosine protein kinase gene.
- Evidence that activation of human T cells by porcine endothelium involves direct recognition of porcine SLA and costimulation by porcine ligands for LFA-1 and CD2.
- Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage.
- Blockade of C5a and C5b-9 generation inhibits leukocyte and platelet activation during extracorporeal circulation.
- Complement-specific antibodies: designing novel anti-inflammatories.
- Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease.
- Molecular and functional analysis of porcine E-selectin reveals a potential role in xenograft rejection.
- Expression of a functional human complement inhibitor in a transgenic pig as a model for the prevention of xenogeneic hyperacute organ rejection.
- Immune response gene function correlates with the expression of an Ia antigen. I. Preferential association of certain Ae and E alpha chains results in a quantitative d...
- Serial MR imaging of experimental autoimmune encephalomyelitis induced by human white matter or by chimeric myelin-basic and proteolipid protein in the common marmoset.
- Determinant spreading associated with demyelination in a nonhuman primate model of multiple sclerosis.
- Myocardial infarction and apoptosis after myocardial ischemia and reperfusion: role of the terminal complement components and inhibition by anti-C5 therapy.
- Presentation of proteolipid protein epitopes and B7-1-dependent activation of encephalitogenic T cells by IFN-gamma-activated SJL/J astrocytes.
- Immune tolerance mediated by recombinant proteolipid protein prevents experimental autoimmune encephalomyelitis.
- Required early complement activation in contact sensitivity with generation of local C5-dependent chemotactic activity, and late T cell interferon gamma: a possible in...
- Humanized porcine VCAM-specific monoclonal antibodies with chimeric IgG2/G4 constant regions block human leukocyte binding to porcine endothelial cells.
- Inhibition of complement activity by humanized anti-C5 antibody and single-chain Fv.
- The role of Fas in autoimmune diabetes.
- Treatment of experimental encephalomyelitis with a novel chimeric fusion protein of myelin basic protein and proteolipid protein.
- Amelioration of lupus-like autoimmune disease in NZB/WF1 mice after treatment with a blocking monoclonal antibody specific for complement component C5.
- Porcine vascular cell adhesion molecule (VCAM) mediates endothelial cell adhesion to human T cells. Development of blocking antibodies specific for porcine VCAM.
- Monoclonal antibodies directed against human C5 and C8 block complement-mediated damage of xenogeneic cells and organs.
- Complement inhibition with an anti-C5 monoclonal antibody prevents acute cardiac tissue injury in an ex vivo model of pig-to-human xenotransplantation.
- Phenotypic and functional analysis of positive selection in the gamma/delta T cell lineage.
- Evidence for programmed cell death of self-reactive gamma delta T cell receptor-positive thymocytes.
- Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor...
- Generation of an HLA-restricted cytotoxic T cell line reactive against cultured tumor cells from a patient infected with human T cell leukemia/lymphoma virus.
- Development and characterization of interleukin-2-independent antigen-specific human T cell clones that produce multiple lymphokines.
- Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules.
- Helper T cells specific for protein antigens: role of self major histocompatibility complex and immunoglobulin gene products.
- Self-recognition specificity expressed by T cells from nude mice. Absence of detectable Ia-restricted T cells in nude mice that do exhibit self-K/D-restricted T cell r...
- Identification of distinct predominant epitopes recognized by myoglobin-specific T cells under the control of different Ir genes and characterization of representative...
- The relationship between immune interferon production and proliferation in antigen-specific, MHC-restricted T cell lines and clones.
- Clonal analysis of the major histocompatibility complex restriction and the fine specificity of antigen recognition in the T cell proliferative response to cytochrome C.
- The major B and T cell determinant on pigeon cytochrome c in B10.a mice.
- The fine specificity of antigen and Ia determinant recognition by T cell hybridoma clones specific for pigeon cytochrome c.
- The T lymphocyte response to cytochrome C. III. Relationship of the fine specificity of antigen recognition to major histocompatibility complex genotype.
- Contribution of antigen-presenting cell major histocompatibility complex gene products to the specificity of antigen-induced T cell activation.
- Immune response gene function correlates with the expression of an Ia antigen. II. A quantitative deficiency in Ae:E alpha complex expression causes a corresponding de...
- Antigen-specific T cell clones restricted to unique F1 major histocompatibility complex determinants. Inhibition of proliferation with monoclonal anti-Ia antibody.
- The T lymphocyte response to cytochrome c--II. Molecular characterization of a pigeon cytochrome c determinant recognized by proliferating T lymphocytes of the B10.A m...
- Monoclonal antibody against an Ir gene product?
- Immune T cells reactive against human T-cell leukaemia/lymphoma virus.
- Isolation of HTLV-transformed B-lymphocyte clone from a patient with HTLV-associated adult T-cell leukaemia.
- Bone marrow-derived thymic antigen-presenting cells determine self-recognition of Ia-restricted T lymphocytes.
- Monoclonal antibody imaging of human melanoma. Radioimmunodetection by subcutaneous or systemic injection.
- Nodular lymphomas: current concepts.
- Cloning with antigens and interleukin 2 of murine T lymphocytes having distinct functions.
- Major histocompatibility complex-linked specificity of gamma delta receptor-bearing T lymphocytes.
- Expression of MEL-14 antigen is not an absolute requirement for dissemination to lymph nodes after adoptive transfer of murine T lymphocyte clones.
- Influence of bone marrow-derived Ia-bearing cells on the selection of the T-cell repertoire.
- Distinct mechanisms of c-myc and lymphokine gene expression in an antigen specific T cell clone.
- Antigen-driven T cell clones can proliferate in vivo, eradicate disseminated leukemia, and provide specific immunologic memory.
- Distinct signals are required for proliferation and lymphokine gene expression in murine T cell clones.
- Generation of diversity in T cell receptor repertoire specific for pigeon cytochrome c.
- Correlations between T-cell specificity and the structure of the antigen receptor.
- The B10.A mouse B cell response to pigeon cytochrome c is directed against the same area of the protein that is recognized by B10.A T cells in association with the Ek ...
- Adoptive chemoimmunotherapy of murine leukemia: dissemination, survival, and function of helper T lymphocyte clones.
- Expression of two distinct T cell receptor alpha/beta heterodimers by an antigen-specific T cell clone.
- Self-tolerance alters T-cell receptor expression in an antigen-specific MHC restricted immune response.
- Structure and specificity of T cell receptor gamma/delta on major histocompatibility complex antigen-specific CD3+, CD4-, CD8- T lymphocytes.
- The influence of MHC gene products on the generation of an antigen-specific T-cell repertoire.
- Selection of amino acid sequences in the beta chain of the T cell antigen receptor.
- The structure of the T cell receptor for antigen is correlated with T cell specificity.
- Adoptive chemoimmunotherapy of murine leukemia with helper T lymphocyte clones.
- TCR gamma delta cells--minor redundant T cell subset or specialized immune system component?
- Distinct proliferative T cell clonotypes are generated in response to a murine retrovirus-induced syngeneic T cell leukemia: viral gp70 antigen-specific MT4+ clones an...
- A TCR gamma delta cell recognizing a novel TL-encoded gene product.
- Structure and specificity of a class II MHC alloreactive gamma delta T cell receptor heterodimer.
- Phenotypic and functional analysis of murine CD3+,CD4-,CD8- TCR-gamma delta-expressing peripheral T cells.
- Thymic requirement for clonal deletion during T cell development.
- Diversity and antigen specificity of the T cell receptor.
- The influence of self-MHC and non-MHC antigens on the selection of an antigen-specific T cell receptor repertoire.
- Helper-independent CD8+ cytotoxic T lymphocytes express IL-1 receptors and require IL-1 for secretion of IL-2.
- Two distinct mechanisms account for the immune response (Ir) gene control of the T cell response to pigeon cytochrome c.
- The molecular basis of alloreactivity in antigen-specific, major histocompatibility complex-restricted T cell clones.
- Adoptive immunotherapy of a syngeneic murine leukemia with a tumor-specific cytotoxic T cell clone and recombinant human interleukin 2: correlation with clonal IL 2 re...
- T cell clones to two major T cell epitopes of myoglobin: effect of I-A/I-E restriction on epitope dominance.
- In vivo induction of anergy in peripheral V beta 8+ T cells by staphylococcal enterotoxin B.
Schools
Perelman School of Medicine University of Pennsylvania
Doctors Specialties
- Medical Oncology
- Oncology
Accepted Insurances
Awards
- Elected Member
Education
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University of Chicago -
Perelman School of Medicine at the University of Pennsylvania