Assistant Professor, Pediatrics, Ohio State University College of Medicine

Neonat/Perinatology

Dr. Louis G. Chicoine, MD

Dr. Louis G. Chicoine works in the field of Neonat/Perinatology. Louis Chicoine is a published doctor and has 49 publications published. The lastest was: 'Maintained upregulation of pulmonary eNOS gene and protein expression during recovery from chronic hypoxia.'

Publications

Predicting death or extended length of stay in infants with congenital diaphragmatic hernia.
Resveratrol prevents hypoxia-induced arginase II expression and proliferation of human pulmonary artery smooth muscle cells via Akt-dependent signaling.
Asymmetric dimethyl arginine does not inhibit arginase activity and is pro-proliferative in pulmonary endothelial cells.
Lung Development Alterations in Newborn Mice after Recovery from Exposure to Sublethal Hyperoxia.
Vascular delivery of rAAVrh74.MCK.GALGT2 to the gastrocnemius muscle of the rhesus macaque stimulates the expression of dystrophin and laminin Î±2 surrogates.
Identification of the Nodose Ganglia and TRPV1 in Swine.
Chronic hypoxia decreases arterial and venous compliance in isolated perfused rat lungs: an effect that is reversed by exogenous L-arginine.
Overexpression of cationic amino acid transporter-1 increases nitric oxide production in hypoxic human pulmonary microvascular endothelial cells.
Systemic Gene Delivery in Large Species for Targeting Spinal Cord, Brain, and Peripheral Tissues for Pediatric Disorders.
Nitric oxide suppression of cellular proliferation depends on cationic amino acid transporter activity in cytokine-stimulated pulmonary endothelial cells.
AAV-mediated gene therapy to the isolated limb in rhesus macaques.
Down syndrome patients with pulmonary hypertension have elevated plasma levels of asymmetric dimethylarginine.
Modified surface coatings and their effect on drug adsorption within the extracorporeal life support circuit.
Inhaled nitric oxide prevents 3-nitrotyrosine formation in the lungs of neonatal mice exposed to >95% oxygen.
Mice deficient in Mkp-1 develop more severe pulmonary hypertension and greater lung protein levels of arginase in response to chronic hypoxia.
Hypoxia-induced proliferation of human pulmonary microvascular endothelial cells depends on epidermal growth factor receptor tyrosine kinase activation.
Persistent expression of FLAG-tagged micro dystrophin in nonhuman primates following intramuscular and vascular delivery.
Is resveratrol the magic bullet for pulmonary hypertension?
Overexpression of Galgt2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type mice.
Cytokine-induced arginase activity in pulmonary endothelial cells is dependent on Src family tyrosine kinase activity.
Deficiency of mitogen-activated protein kinase phosphatase-1 results in iNOS-mediated hypotension in response to low-dose endotoxin.
Maturational changes in the regulation of pulmonary vascular tone by nitric oxide in neonatal rats.
Role of DDAH-1 in lipid peroxidation product-mediated inhibition of endothelial NO generation.
Gene therapy for duchenne muscular dystrophy: expectations and challenges.
MKP-1 switches arginine metabolism from nitric oxide synthase to arginase following endotoxin challenge.
Assessing heparin dosing in neonates on venoarterial extracorporeal membrane oxygenation.
Gene transfer with inducible nitric oxide synthase decreases production of urea by arginase in pulmonary arterial endothelial cells.
Cytokine-induced endothelial arginase expression is dependent on epidermal growth factor receptor.
Intratracheal adenoviral-mediated delivery of iNOS decreases pulmonary vasoconstrictor responses in rats.
Arginase inhibition increases nitric oxide production in bovine pulmonary arterial endothelial cells.
L-lysine decreases nitric oxide production and increases vascular resistance in lungs isolated from lipopolysaccharide-treated neonatal pigs.
Developmental differences in pulmonary eNOS expression in response to chronic hypoxia in the rat.
Hypoxia-induced pulmonary endothelin-1 expression is unaltered by nitric oxide.
L-Arginine uptake and metabolism following in vivo silica exposure in rat lungs.
A translational approach for limb vascular delivery of the micro-dystrophin gene without high volume or high pressure for treatment of Duchenne muscular dystrophy.
Nonrandom utilization of acetylation sites in histones isolated from Tetrahymena. Evidence for functionally distinct H4 acetylation sites.
Micronuclei and the cytoplasm of growing Tetrahymena contain a histone acetylase activity which is highly specific for free histone H4.
Enzyme activity dot blots: a rapid and convenient assay for acetyltransferase or protein kinase activity immobilized on nitrocellulose.
A single histone acetyltransferase from Tetrahymena macronuclei catalyzes deposition-related acetylation of free histones and transcription-related acetylation of nucl...
Regulation of histone acetylation during macronuclear differentiation in Tetrahymena: evidence for control at the level of acetylation and deacetylation.
Deposition-related histone acetylation in micronuclei of conjugating Tetrahymena.
Modulation of linker histones during development in Tetrahymena: selective elimination of linker histone during the differentiation of new macronuclei.
Proteolytic processing of h1-like histones in chromatin: a physiologically and developmentally regulated event in Tetrahymena micronuclei.
Unaltered vasoconstrictor responsiveness after iNOS inhibition in lungs from chronically hypoxic rats.
Maintained upregulation of pulmonary eNOS gene and protein expression during recovery from chronic hypoxia.
Cytokine treatment increases arginine metabolism and uptake in bovine pulmonary arterial endothelial cells.
Effect of microwave irradiation on antibody labeling efficiency when applied to ultrathin cryosections through fixed biological material.
Left brachial artery thrombus, left axillary vein thrombus, and stroke in a neonate with factor V Leiden mutation.

Schools

University Of Texas Medical Branch At Galveston

Doctors Specialties

Neonatal Medicine
Neonat/Perinatology

Accepted Insurances

Education

University of Colorado
Stanford University
University of Texas Medical Branch

Hospital

Nationwide Children's Hospital
Ohio State University Wexner Medical Center

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