Section Chief, Clinical Lab Genetics

Pathology

Linda Cooley works in the field of Pathology. She attended Baylor College of Medicine. Linda D. Cooley, MD has written publications. She has 45 publications published with PubMed. The lastest paper is: 'Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic...'

Publications

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• Spitzoid melanoma arising as a second malignancy in a child with Li-Fraumeni syndrome.
• American College of Medical Genetics and Genomics technical standards and guidelines: microarray analysis for chromosome abnormalities in neoplastic disorders.
• Higher dose imatinib for children with de novo chronic phase chronic myelogenous leukemia: A report from the Children's Oncology Group.
• An interstitial 15q11-q14 deletion: expanded Prader-Willi syndrome phenotype.
• Quantitative real-time polymerase chain reaction for the verification of genomic imbalances detected by microarray-based comparative genomic hybridization.
• Validation of the Agilent 244K oligonucleotide array-based comparative genomic hybridization platform for clinical cytogenetic diagnosis.
• Autistic and dysmorphic features associated with a submicroscopic 2q33.3-q34 interstitial deletion detected by array comparative genomic hybridization.
• Specific extra chromosomes occur in a modal number dependent pattern in pediatric acute lymphoblastic leukemia.
• Prognostic significance of cytogenetically detected chromosome 21 anomalies in childhood acute lymphoblastic leukemia: a Pediatric Oncology Group study.
• Clear cell sarcoma of tendons and aponeuroses: a review.
• HER-2 fluorescence in situ hybridization: results from the survey program of the College of American Pathologists.
• A Newborn with Genital Ambiguity, 45,X/46,XY Mosaicism, a Jumping Chromosome Y, and Congenital Adrenal Hyperplasia.
• Primary Ewing's sarcoma of the bladder associated with an elevated antinuclear antibody titer.
• Pancytopenia with chromosomal fragility: vitamin B12 deficiency.
• Drosophila quail, a villin-related protein, bundles actin filaments in apoptotic nurse cells.
• Infant cardiac fibroma with clonal t(1;9)(q32;q22) and review of benign fibrous tissue cytogenetics.
• Isochromosome 7q in childhood myelodysplastic syndrome.
• Immunohistochemical determination of HER-2/neu expression in invasive breast carcinoma.
• Cytogenetic analysis of 120 primary pediatric brain tumors and literature review.
• Donor cell leukemia: report of a case occurring 11 years after allogeneic bone marrow transplantation and review of the literature.
• Atypical cytogenic aberrations in two childhood peripheral primitive neuroectodermal tumors.
• Cytogenetic characterization of three human and three rat medullary thyroid carcinoma cell lines.
• Extensive analysis of mosaicism in a case of Turner syndrome: the experience of 287 cytogenetic laboratories. College of American Pathologists/American College of Medi...
• The utility of spectral karyotyping in the cytogenetic analysis of newly diagnosed pediatric acute lymphoblastic leukemia.
• Dermatofibrosarcoma protuberans in the breast of a 2-year-old girl.
• Angiomatoid fibrous histiocytoma with t(2;22)(q33;q12.2) and EWSR1 gene rearrangement.
• Juxtaglomerular cell tumor in an 8-year-old girl.
• Malignant peripheral nerve sheath tumor with a t(X;18).
• Cytogenetic analysis of a scapular chondromyxoid fibroma.
• Cytogenetic demonstration of gene amplification in a primary intracranial germ cell tumor.
• The first recurring chromosome translocation in hepatoblastoma: der(4)t(1;4)(q12;q34).
• Pilot studies for proficiency testing using fluorescence in situ hybridization with chromosome-specific DNA probes: a College of American Pathologists/American College...
• Translocations involving chromosome 12p11-13, methotrexate metabolism, and outcome in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Gr...
• Minimal residual disease testing of acute leukemia by flow cytometry immunophenotyping: a retrospective comparison of detection rates with flow cytometry DNA ploidy or...
• Refining the 22q11.2 deletion breakpoints in DiGeorge syndrome by aCGH.
• The association of the TEL-AML1 chromosomal translocation with the accumulation of methotrexate polyglutamates in lymphoblasts and with ploidy in childhood B-progenito...
• Detection of double minute chromosomes in a child with acute lymphoblastic leukemia.
• Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic...
• Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts and treatment outcome in children with B-progenitor-cell acute lymphoblastic leukemia: a P...
• Problems with ISCN FISH Nomenclature make it not practical for use in clinical test reports or cytogenetic databases [corrected].
• Proficiency testing for laboratories performing fluorescence in situ hybridization with chromosome-specific DNA probes.
• Cytogenetic heteromorphisms: survey results and reporting practices of giemsa-band regions that we have pondered for years.
• Guidance for fluorescence in situ hybridization testing in hematologic disorders.
• Section E6.5 of the ACMG technical standards and guidelines: chromosome studies for solid tumor abnormalities.

Schools

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• Baylor University

• Baylor

Doctors Specialties

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• Clinical Cytogenetics
• Pathology

Accepted Insurances

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Education

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• Baylor College of Medicine

Hospital

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• Children's Mercy Hospitals and Clinics

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