Professor of Anesthesiology and Critical Care Medicine, Associate Professor of Pediatrics, Johns Hopkins University School of Medicine; Co-Director of Research, Division of Pediatric Anesthesiology and Critical Care Medicine, Department of Anesthesiology
Anesthesiology
Dr. Lewis H. Romer, MD
Lewis Romer works in the field of Anesthesiology. He attended Geisel School of Medicine at Dartmouth. Geisel School of Medicine at Dartmouth has a rank of 37 in research and a 29 in primary care Lewis H. Romer is also a published doctor. He has 51 paper published. The most recent paper is: Microinjection of protein tyrosine phosphatases into fibroblasts disrupts focal adhesions and stress fibers.
Publications
- NEDDylation promotes endothelial dysfunction: A role for HDAC2.
- Endothelial Matrix Assembly during Capillary Morphogenesis: Insights from Chimeric TagRFP-Fibronectin Matrix.
- Oriented matrix promotes directional tubulogenesis.
- Frontiers in pulmonary hypertension in infants and children with bronchopulmonary dysplasia.
- Respiratory failure secondary to human metapneumovirus requiring extracorporeal membrane oxygenation in a 32-month-old child.
- Pediatric residents do not feel prepared for the most unsettling situations they face in the pediatric intensive care unit.
- A predictive model of cell traction forces based on cell geometry.
- Integrin alpha2 mediates selective metastasis to the liver.
- Cell traction forces direct fibronectin matrix assembly.
- Micropatterns of an extracellular matrix protein with defined information content.
- Regulation of hyperoxia-induced NADPH oxidase activation in human lung endothelial cells by the actin cytoskeleton and cortactin.
- High fidelity functional patterns of an extracellular matrix protein by electron beam-based inactivation.
- FAK potentiates Rac1 activation and localization to matrix adhesion sites: a role for betaPIX.
- Oxidized low-density lipoprotein-dependent endothelial arginase II activation contributes to impaired nitric oxide signaling.
- An inhibitory role for FAK in regulating proliferation: a link between limited adhesion and RhoA-ROCK signaling.
- Focal adhesions: paradigm for a signaling nexus.
- Signaling pathways involved in adenosine triphosphate-induced endothelial cell barrier enhancement.
- Intracellular interaction of myosin light chain kinase with macrophage migration inhibition factor (MIF) in endothelium.
- Receptor protein tyrosine phosphatase micro regulates the paracellular pathway in human lung microvascular endothelia.
- Shear force at the cell-matrix interface: enhanced analysis for microfabricated post array detectors.
- Protein tyrosine phosphatase activity regulates endothelial cell-cell interactions, the paracellular pathway, and capillary tube stability.
- Caspase-dependent cleavage of myosin light chain kinase (MLCK) is involved in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis.
- Localization of multiple functional domains on human PECAM-1 (CD31) by monoclonal antibody epitope mapping.
- Experimental coexpression of vimentin and keratin intermediate filaments in human melanoma cells augments motility.
- pp60(c-src) and related tyrosine kinases: a role in the assembly and reorganization of matrix adhesions.
- Signals from focal adhesions.
- IFN-gamma and TNF-alpha induce redistribution of PECAM-1 (CD31) on human endothelial cells.
- Endotoxin, tumor necrosis factor, and dexamethasone effects on human endothelial cell fibronectin dynamics: synthesis, matrix assembly, and receptor expression.
- Signaling between the extracellular matrix and the cytoskeleton: tyrosine phosphorylation and focal adhesion assembly.
- Microinjection of antibodies against talin inhibits the spreading and migration of fibroblasts.
- Microinjection of protein tyrosine phosphatases into fibroblasts disrupts focal adhesions and stress fibers.
- Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization.
- Selective fluorescent labeling of S-nitrosothiols (S-FLOS): a novel method for studying S-nitrosation.
- Mitochondrial dysfunction and cytoskeletal disruption during chemical hypoxia to cultured rat hepatic sinusoidal endothelial cells: the pH paradox and cytoprotection b...
- Targeting membrane-localized focal adhesion kinase to focal adhesions: roles of tyrosine phosphorylation and SRC family kinases.
- Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts.
- Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins.
- EndoCAM: a novel endothelial cell-cell adhesion molecule.
- Arginine stimulates intestinal cell migration through a focal adhesion kinase dependent mechanism.
- Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells.
- Tyrosine phosphorylation of Rac1: a role in regulation of cell spreading.
- Paxillin binding is not the sole determinant of focal adhesion localization or dominant-negative activity of focal adhesion kinase/focal adhesion kinase-related nonkin...
- Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation.
- Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.
- The role of caldesmon in the regulation of endothelial cytoskeleton and migration.
- Focal adhesion kinase is involved in type III group B streptococcal invasion of human brain microvascular endothelial cells.
- Endothelial cell adhesion, signaling, and morphogenesis in fibroblast-derived matrix.
- OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling.
- Microelastic properties of lung cell-derived extracellular matrix.
- Single exposure to radiation produces early anti-angiogenic effects in mouse aorta.
Schools
Dartmouth College
University Of Ut Med Center
Doctors Specialties
- Pediatric Critical Care Medicine
- Anesthesiology
Accepted Insurances
Education
-
University of Utah -
Geisel School of Medicine at Dartmouth
Hospital
-
Johns Hopkins Hospital
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