Physician

Neurology

Leslie Shinobu is an expert in the field of Neurology. She went to Vanderbilt University School of Medicine. Leslie A. Shinobu, MD is also published. She has 19 publications published. The lastest publication: "Age-dependent increases in oxidative damage to DNA, lipids, and proteins in human skeletal muscle.'

Publications

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• Rapamycin drives selection against a pathogenic heteroplasmic mitochondrial DNA mutation.
• Surgery for Parkinson Disease in the United States, 1996 to 2000: practice patterns, short-term outcomes, and hospital charges in a nationwide sample.
• Pilot study of granulocyte colony stimulating factor (G-CSF)-mobilized peripheral blood stem cells in amyotrophic lateral sclerosis (ALS).
• Surgical treatment of Parkinson Disease.
• Outcomes following staged bilateral pallidotomy in advanced Parkinson's Disease.
• No difference in plasma or urinary F2-isoprostanes among patients with Huntington's Disease or Alzheimer's Disease and controls.
• Partial deficiency of manganese superoxide dismutase exacerbates a transgenic mouse model of amyotrophic lateral sclerosis.
• Stereotactic pallidotomy performed without using microelectrode guidance in patients with Parkinson's Disease: surgical technique and 2-year results.
• Outcomes assessment for pallidotomy.
• Age-dependent increases in oxidative damage to DNA, lipids, and proteins in human skeletal muscle.
• The importance of accurate lesion placement in posteroventral pallidotomy. Report of two cases.
• Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis.
• Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation.
• Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer Disease.
• Manganese injection into the rat striatum produces excitotoxic lesions by impairing energy metabolism.
• Enhancement of Ca2+-sensitive myosin ATPase activity by cadmium.
• Retraction.
• Elevation of the Hsp70 chaperone does not effect toxicity in mouse models of familial amyotrophic lateral sclerosis.

Schools

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• Vanderbilt University School Of Medicine

• Vanderbilt University Hospitals

• Mass General Hospital

Conditions Treated

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• Dystonia
• Gait Abnormality
• Low Back Pain
• Parkinson's Disease
• View All

Doctors Specialties

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• Neurology

Accepted Insurances

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Education

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• Massachusetts General Hospital
• Vanderbilt University
• Vanderbilt University School of Medicine

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