Physician
Dermatology
Dr. Leonard M. Milstone, MD
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Leonard Milstone practices Dermatology. He studied medicine at Yale University School of Medicine. Yale University School of Medicine is a top medical university. Yale University School of Medicine has a rank of 7 in research and a 57 in primary care He received 2 awards: "CMS Meaningful Use Stage 1 Certification" and "Fellow (FAAD)". Leonard Milstone is also published. He has 100 publications published. The lastest publication: "PURPLE (oops! Atrophie blanche) revisited.' Leonard M. Milstone is registered with Medicare.
Publications
- Expanding the Phenotypic Spectrum of Olmsted Syndrome.
- Gene expression profiling in pachyonychia congenita Skin.
- Crystal Structure of Human Profilaggrin S100 Domain and Identification of Target Proteins Annexin II, Stratifin and hsp27.
- Phenotypic Expansion in Ichthyosis With Confetti.
- Report of the 10th annual international pachyonychia congenita consortium meeting.
- Improving outcomes for harlequin ichthyosis.
- Mutations in TGM1 in Ecuadorians with autosomal recessive congenital ichthyosis.
- Harlequin Ichthyosis: Neonatal Management and Identification of a New ABCA12 Mutation.
- Topical tazarotene for the treatment of ectropion in ichthyosis.
- Local delivery of gene-modifying triplex-forming molecules to the epidermis.
- Management of ichthyosis and related conditions gene-based diagnosis and emerging gene-based therapy.
- Impact of epidermal desquamation on tissue stores of iron.
- Interferon-? Release Assay.
- Pityriasis rubra pilaris: the clinical context of acantholysis and other histologic features.
- An appraisal of oral retinoids in the treatment of pachyonychia congenita.
- Development of Quantitative Molecular Clinical End Points for siRNA Clinical Trials.
- A large mutational study in pachyonychia congenita.
- Meeting report from Frontiers in Ichthyosis Research.
- Mitotic recombination in patients with ichthyosis causes reversion of dominant mutations in KRT10.
- Scaly Skin and bath pH: rediscovering baking soda.
- First-in-human mutation-targeted siRNA phase Ib trial of an inherited Skin disorder.
- Single-nucleotide-specific siRNA targeting in a dominant-negative Skin model.
- Aaron Lerner remembered.
- Barrier dysfunction and pathogenesis of neutral lipid storage disease with ichthyosis (Chanarin-Dorfman syndrome).
- Obstacles to translation conference.
- Stratum-specific expression of human transferrin receptor increases iron in mouse epidermis.
- Iron in Skin of mice with three etiologies of systemic iron overload.
- Gene therapy for autosomal dominant disorders of keratin.
- Clinical and pathological features of pachyonychia congenita.
- Treatment of pachyonychia congenita.
- Isotretinoin does have an adverse effect on bone mineral density.
- Is retinoid-induced osteopenia reversible?
- Clinical and in vitro responses of bilayered Skin construct (graftSkin) to meshing.
- Imaging Functional Nucleic Acid Delivery to Skin.
- Conversion of isatin to isatate as related to growth promotion in Avena coleoptile and pisum stem sections.
- Hyaluronidase from infective Ancylostoma hookworm larvae and its possible function as a virulence factor in tissue invasion and in cutaneous larva migrans.
- Metalloproteases of infective Ancylostoma hookworm larvae and their possible functions in tissue invasion and ecdysis.
- Keratins in cultivated human keratinocytes are stable.
- Skin-derived fibroblasts respond to human parathyroid hormone-like adenylate cyclase-stimulating proteins.
- Identification of a cDNA encoding a parathyroid hormone-like peptide from a human tumor associated with humoral hypercalcemia of malignancy.
- Two distinct tumor-derived, parathyroid hormone-like peptides result from alternative ribonucleic acid splicing.
- The influence of retinoids on cultivated human keratinocytes.
- Changing concepts of keratin.
- Thymidine phosphorylase in human epidermal keratinocytes.
- A parathyroid hormone-like protein from cultured human keratinocytes.
- Native and a synthetic analogue of the malignancy-associated parathyroid hormone-like protein have in vitro transforming growth factor-like properties.
- Dipyridamole potentiates the growth-inhibitory action of methotrexate and 5-fluorouracil in human keratinocytes in vitro.
- Characterization of a parathyroid hormonelike peptide secreted by human keratinocytes.
- Local and systemic implications of thymidine catabolism by human keratinocytes.
- Effector functions of epidermal keratinocytes.
- Differentiation of lens fibers in explanted embryonic chick lens epithelia.
- Release of virus inhibitor from tuberculin-sensitized peritoneal Cells stimulated by antigen.
- Heterogeneity of Basal keratinocytes: nonrandom distribution of thymidine-labeled Basal cells in confluent cultures is not a technical artifact.
- Skin potions.
- Prescribing retinoids. The art and the science.
- In vivo fluorescence of human Skin. A potential marker of photoaging.
- Human keratinocytes catabolize thymidine.
- Measurement of retinoid effects on epidermal renewal.
- Immunoaffinity purification of parathyroid hormone-related protein from bovine milk and human keratinocyte-conditioned medium.
- Immunohistochemical localization of parathyroid hormone-related protein (PTHRP) in normal human Skin.
- Glycosylation of parathyroid hormone-related peptide secreted by human epidermal keratinocytes.
- Quantitation of cross-linked protein: an alternative to counting cornified envelopes as an index of keratinocyte differentiation.
- Methotrexate induces differentiation of human keratinocytes.
- Antiviral activity of 5-iodo-2''-deoxyuridine and related drugs in human keratinocytes infected in vitro with herpes simplex virus type 1.
- Human dermatosparaxis: a form of Ehlers-Danlos syndrome that results from failure to remove the amino-terminal propeptide of type I procollagen.
- Analysis of PTHRP binding and signal transduction mechanisms in benign and malignant squamous Cells.
- Parathyroid hormone-related protein. Evidence for secretion of a novel mid-region fragment by three different Cell types.
- Identification and characterization of a Cell surface proteoglycan on keratinocytes.
- Serum parathyroid hormone level is elevated in some patients with disorders of keratinization.
- The core protein of epican, a heparan sulfate proteoglycan on keratinocytes, is an alternative form of CD44.
- Delta-crystallin mRNA in chick lens Cells: mRNA accumulates during differential stimulation of delta-crystallin synthesis in cultured Cells.
- Rates of protein synthesis in explanted embryonic chick lens epithelia: differential stimulation of delta-crystallin synthesis.
- delta-Crystallin gene expression in embryonic chick lens epithelia cultured in the presence of insulin.
- Delayed-onset pachyonychia congenita associated with a novel mutation in the central 2B domain of keratin 16.
- Photodegraded nifedipine stimulates uptake and retention of iron in human epidermal keratinocytes.
- Diagnosis of autosomal recessive lamellar ichthyosis with mutations in the TGM1 gene.
- Growth and differentiation regulate CD44 expression on human keratinocytes.
- Expression and localization of thymidine phosphorylase/platelet-derived endothelial Cell growth factor in skin and cutaneous tumors.
- Bone densities in patients receiving isotretinoin for cystic acne.
- PURPLE (oops! Atrophie blanche) revisited.
- Pneumocystis carinii pneumonia complicating methotrexate treatment of pityriasis rubra pilaris.
- CD44 expression on epidermal melanocytes.
- Secondary hyperparathyroidism in patients with ichthyosis is not caused by vitamin D deficiency or ingestion of retinoids.
- Response of stratified cultures of human keratinocytes to disruption of proteoglycan synthesis by p-nitrophenyl-beta-D-xylopyranoside.
- Dermatosparaxis in children. A case report and review of the newly recognized phenotype.
- Keratinocytes differentiate in response to inhibitors of deoxyribonucleotide synthesis.
- Generalized linear poroKeratosis treated with etretinate.
- Epican, a heparan/chondroitin sulfate proteoglycan form of CD44, mediates Cell-Cell adhesion.
- Overexpression of parathyroid hormone-related protein in the Skin of transgenic mice interferes with hair follicle development.
- Histologic findings in acute HIV exanthem.
- Isolation and characterization of two polypeptides that form intermediate filaments in bovine esophageal epithelium.
- Different polypeptides form the intermediate filaments in bovine hoof and esophageal epithelium and in aortic endothelium.
- Retinoic acid causes premature desquamation of Cells from confluent cultures of stratified squamous epithelia.
- Premature epiphyseal closure in a child receiving oral 13-cis-retinoic acid.
- Population dynamics in cultures of stratified Squamous epithelia.
- Classification and therapy of atrophie blanche.
- 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces hyperplasia in confluent cultures of human keratinocytes.
- Epidermal Cell confluence and implications for a two-step mechanism of wound closure.
- GABA from putrescine is bound in macromolecular form in keratinocytes.
Schools
Yale University
Oreg
Yale New Haven Hospital
National Institute Of Health
Procedures Preformed
- Destruction of Benign Skin Lesion
- Destruction of Malignant Skin Lesion
Conditions Treated
- Actinic Keratosis
- Athlete's Foot
- Basal Cell Carcinoma
- Benign Skin Lesion
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Doctors Specialties
- Dermatology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Fellow (FAAD)
Education
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Yale-New Haven Hospital -
Oregon Health & Science University -
Yale University School of Medicine
Hospital
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Yale-New Haven Hospital
Drug Facts
| NPI NUMBER | 1336123629 | |
| NPPES Provider LastName | MILSTONE | |
| NPPES Provider FirstName | LEONARD | |
| NPPES Provider ZIPCode | 06519 | |
| NPPES Provider State | CT | |
| Specialty Description | Dermatology | |
| Total Claim Count | 159.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1336123629 |
| Last Name Of The Provider | MILSTONE |
| First Name Of The Provider | LEONARD |
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