Physician
Pathology
Dr. Leonard J. Medeiros, MD
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Leonard Medeiros is an expert in the field of Pathology. He went to University of Massachusetts Medical School. University of Massachusetts Medical School is ranked 49/12 in Research/PrimaryCare. Dr. Leonard J. Medeiros is also a published MD. He has 108 paper published. The most recent paper is: Dyspoietic changes associated with hepatosplenic T-cell lymphoma are not a manifestation of a myelodysplastic syndrome: analysis of 25 patients. He accepts all Medicare patients.
Publications
- Crystal-storing histiocytosis: a clinicopathological study of 13 cases.
- Doxorubicin-Based Chemotherapy and Radiation Therapy Produces Favorable Outcomes in Limited-Stage Plasmablastic Lymphoma: A Single-Institution Review.
- High Levels of Regulatory T Cells in Blood Are a Poor Prognostic Factor in Patients With Diffuse Large B-Cell Lymphoma.
- Lymphomatous variant of hairy cell leukaemia: a distinctive presentation mimicking low-grade B-cell Lymphoma.
- Primary central nervous system diffuse large B-cell Lymphoma has poorer immune cell infiltration and prognosis than its peripheral counterpart.
- Impact of trisomy 8 on treatment response and survival of patients with chronic myelogenous Leukemia in the era of tyrosine kinase inhibitors.
- Mixed T Lymphocyte Chimerism after Allogeneic Hematopoietic Transplantation Is Predictive for Relapse of Acute Myeloid Leukemia and Myelodysplastic Syndromes.
- Clinical features, tumor biology, and prognosis associated with MYC rearrangement and Myc overexpression in diffuse large B-cell Lymphoma patients treated with rituxim...
- De Novo MYC and BCL2 Double-hit B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) in Pediatric and Young Adult Patients Associated With Poor Prognosis.
- Prognostic impact of concurrent MYC and BCL6 rearrangements and expression in de novo diffuse large B-cell Lymphoma.
- T-Lymphoblastic Leukemia/Lymphoma.
- Hematolymphoid Neoplasms Associated With Rearrangements of PDGFRA, PDGFRB, and FGFR1.
- Phase II study of HCVIDD/MA in patients with newly diagnosed peripheral T-cell Lymphoma.
- Comparison of Next-generation Sequencing Mutation Profiling With BRAF and IDH1 Mutation-specific Immunohistochemistry.
- Shared clonality in distinctive lesions of Lymphomatoid papulosis and mycosis fungoides occurring in the same patients suggests a common origin.
- Mutational profiling of therapy-related myelodysplastic syndromes and Acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases.
- The clinical significance of negative flow cytometry immunophenotypic results in a morphologically scored positive bone marrow in patients following treatment for acut...
- CD5-positive follicular Lymphoma: clinicopathologic correlations and outcome in 88 cases.
- Benefit of Consolidative Radiation Therapy for Primary Bone Diffuse Large B-Cell Lymphoma.
- Chronic Myelomonocytic Leukemia with Nucleophosmin (NPM1) Mutation.
- B-cell Lymphomas with concurrent MYC and BCL2 abnormalities other than translocations behave similarly to MYC/BCL2 double-hit Lymphomas.
- Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors.
- Epstein-Barr virus-positive plasmacytoma in immunocompetent patients.
- Identification of a novel fusion gene, IRF2BP2-RARA, in Acute promyelocytic leukemia.
- Comparison of Survival in Patients with T Cell Lymphoma after Autologous and Allogeneic Stem Cell Transplantation as a Frontline Strategy or in Relapsed Disease.
- Isolated +15 in bone marrow: Disease-associated or a benign finding?
- Flow cytometry immunophenotypic analysis of philadelphia-negative Myeloproliferative neoplasms: Correlation with histopathologic features.
- Radiation therapy is an effective modality in the treatment of mantle cell Lymphoma, even in heavily pretreated patients.
- A novel recurrent NPM1-TYK2 gene fusion in cutaneous CD30-positive lymphoproliferative Disorders.
- Differential Expression of CD200 in B-Cell Neoplasms by Flow Cytometry Can Assist in Diagnosis, Subclassification, and Bone Marrow Staging.
- Identification of clinically important chromosomal aberrations in Acute myeloid leukemia by array-based comparative genomic hybridization.
- Acquired B Cell immunophenotype of follicular dendritic Cells in a B Cell-depleted lymph node after treatment with rituximab.
- The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK+ anaplastic large cell Lymphoma.
- MLL gene amplification in Acute myeloid leukemia and myelodysplastic syndromes is associated with characteristic clinicopathological findings and TP53 gene mutation.
- Clinical Implications of Phosphorylated STAT3 Expression in De Novo Diffuse Large B-cell Lymphoma.
- Identification of putative pathogenic microRNA and its downstream targets in anaplastic Lymphoma kinase-negative anaplastic large cell Lymphoma.
- Clinical massively parallel next-generation sequencing analysis of 409 cancer-related genes for mutations and copy number variations in solid tumours.
- Flow cytometric immunophenotypic analysis of systemic mastocytosis involving bone marrow.
- Plasma circulating-microRNA profiles are useful for assessing prognosis in patients with cytogenetically normal Myelodysplastic syndromes.
- Impact of induction regimen and stem cell transplantation on outcomes in double-hit Lymphoma: a multicenter retrospective analysis.
- Utility of Quantitative Flow Cytometry Immunophenotypic Analysis of CD5 Expression in Small B-Cell Neoplasms.
- Solitary plasmacytoma of the index finger.
- Myelomastocytic Leukemia With Aberrant CD25 Expression: Case Report and Review of the Literature.
- Monoclonality and cytogenetic abnormalities in hyaline vascular Castleman Disease.
- Prevalence and clinical implications of cyclin D1 expression in diffuse large B-cell Lymphoma (DLBCL) treated with immunochemotherapy: A report from the International ...
- Clinically silent clonal cytogenetic abnormalities arising in patients treated for lymphoid neoplasms.
- Double hit Lymphoma: the MD Anderson Cancer Center clinical experience.
- BRAF kinase domain mutations are present in a subset of chronic myelomonocytic Leukemia with wild-type RAS.
- Integrated genomic sequencing reveals mutational landscape of T-cell prolymphocytic Leukemia.
- Epstein-Barr virus-positive nodular lymphocyte predominant Hodgkin Lymphoma.
- Cytogenetic risk stratification of 417 patients with chronic myelomonocytic Leukemia from a single institution.
- Positron Emission Tomography/Computed Tomography Findings During Therapy Predict Outcome in Patients With Diffuse Large B-Cell Lymphoma Treated With Chemotherapy Alone...
- Quantitative assessment of mutant allele burden in solid tumors by semiconductor-based next-generation sequencing.
- Next-generation sequencing-based multigene mutational screening for Acute myeloid leukemia using MiSeq: applicability for diagnostics and disease monitoring.
- c-JUN N-terminal kinase (JNK) is activated and contributes to tumor cell proliferation in classical Hodgkin Lymphoma.
- Indolent peripheral T-cell Lymphoma involving the gastrointestinal tract.
- Prevalence and Clinical Implications of Epstein-Barr Virus Infection in de novo Diffuse Large B-Cell Lymphoma in Western Countries.
- Lymphoma With Features Intermediate Between Aggressive T-Large Granular Lymphocytic Leukemia and Hepatosplenic T-Cell Lymphoma: A Diagnostic Dilemma?
- The Effect of Peritransplant Minimal Residual Disease in Adults With Acute Lymphoblastic Leukemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation.
- Rearrangements of MYC gene facilitate risk stratification in diffuse large B-cell Lymphoma patients treated with rituximab-CHOP.
- Breast Implant-Associated Anaplastic Large-Cell Lymphoma: Long-Term Follow-Up of 60 Patients.
- Iatrogenic Immunodeficiency-associated Classical Hodgkin Lymphoma: Clinicopathologic Features of 54 Cases Reported in the Literature.
- Bone marrow fibrosis in patients with primary Myelodysplastic syndromes has prognostic value using current therapies and new risk stratification systems.
- Immunostaining for Rapid Diagnosis of Acute Promyelocytic Leukemia with the Tetramethylrhodamine-5-Isothiocyanate-Conjugated Anti-Promyelocytic Leukemia Monoclonal Ant...
- Clinicopathologic Features of CD5-Positive Nodal Marginal Zone Lymphoma.
- Metastatic splenic angiosarcoma presenting with thrombocytopenia and bone marrow fibrosis mimicking idiopathic thrombocytopenic purpura and primary myelofibrosis: a di...
- Cytarabine, Ki-67, and SOX11 in patients with mantle cell Lymphoma receiving rituximab-containing autologous stem cell transplantation during first remission.
- CXC Chemokine Receptor 4 Expression, CXC Chemokine Receptor 4 Activation, and Wild-Type Nucleophosmin Are Independently Associated With Unfavorable Prognosis in Patien...
- B Acute lymphoblastic leukemia with t(14;19)(q32;p13.1) involving IGH/EPOR: a clinically aggressive subset of disease.
- Clonally related composite follicular Lymphoma and mantle cell Lymphoma with clinicopathologic features and biological implications.
- Long term results of a phase 2 study of vincristine sulfate liposome injection (Marqibo(®) ) substituted for non-liposomal vincristine in cyclophosphamide, doxorubicin...
- Clinical validation of a next-generation sequencing screen for mutational hotspots in 46 cancer-related genes.
- MYC/BCL2 Double-Hit High-Grade B-Cell Lymphoma.
- CD105 (Endoglin) Is Highly Overexpressed in a Subset of Cases of Acute Myeloid Leukemias.
- MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell Lymphoma patients treated with rituximab-CHOP immunochemotherapy.
- MicroRNA signatures and treatment response in patients with advanced classical Hodgkin Lymphoma.
- Value of Oligonucleotide-Based Array Comparative Genomic Hybridization for Diagnosis of Acute Promyelocytic Leukemia in a Patient Negative for t(15;17)(q24.1;q21.2)/Pr...
- Classical hodgkin Lymphoma arising in the setting of iatrogenic immunodeficiency: a clinicopathologic study of 10 cases.
- Next-generation sequencing-based multi-gene mutation profiling of solid tumors using fine needle aspiration samples: promises and challenges for routine clinical diagn...
- TET2 mutations, myelodysplastic features, and a distinct immunoprofile characterize blastic plasmacytoid dendritic Cell neoplasm in the bone marrow.
- The Impact of MYC Rearrangements and "Double Hit" Abnormalities in Diffuse Large B-Cell Lymphoma.
- Application of the International Prognostic Scoring System-Revised in therapy-related myelodysplastic syndromes and oligoblastic Acute myeloid leukemia.
- Plasma Cell enrichment enhances detection of high-risk cytogenomic abnormalities by fluorescence in situ hybridization and improves risk stratification of patients wit...
- The clinical importance of moderate/severe bone marrow fibrosis in patients with therapy-related Myelodysplastic syndromes.
- EBV-positive diffuse large B-cell Lymphoma of the elderly.
- Double-hit of FLT3 gene in a fatal case of Acute myemonocytic leukaemia.
- Absence of terminal deoxynucleotidyl transferase expression identifies a subset of high-risk adult T-lymphoblastic Leukemia/lymphoma.
- Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis.
- Chronic lymphocytic Leukemia with t(14;18)(q32;q21).
- Myeloid Sarcoma of the Head and Neck Region.
- Single nucleotide variation in the TP53 3' untranslated region in diffuse large B-cell Lymphoma treated with rituximab-CHOP: a report from the International DLBCL Ritu...
- High-dose chemotherapy and Autologous Stem Cell Transplantation For Nodular Lymphocyte-Predominant Hodgkin Lymphoma (NLPHL).
- Systemic mastocytosis with associated clonal hematological non-mast cell lineage Disease: Clinical significance and comparison of chomosomal abnormalities in SM and AH...
- Patients with diffuse large B-cell Lymphoma of germinal center origin with BCL2 translocations have poor outcome, irrespective of MYC status: a report from an Internat...
- Phenotypic evolution in a case of peripheral T-cell Lymphoma suggests the presence of tumor heterogeneity.
- Potential therapeutic biomarkers in plasma Cell myeloma: A flow cytometry study.
- MYC/BCL2 protein co-expression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell Lymphoma and demonstrates high-risk gene expres...
- Differential expression of aurora-A kinase in T-cell Lymphomas.
- Therapy-related Myeloid neoplasms with isolated del(20q): comparison with cases of de novo myelodysplastic syndrome with del(20q).
- Dyspoietic changes associated with hepatosplenic T-cell Lymphoma are not a manifestation of a myelodysplastic syndrome: analysis of 25 patients.
- High-grade B-cell Lymphoma With MYC Rearrangement and Without BCL2 and BCL6 Rearrangements Is Associated With High P53 Expression and a Poor Prognosis.
- Impact of oncogene rearrangement patterns on outcomes in patients with double-hit non-Hodgkin Lymphoma.
- Principles of analytical validation of next-generation sequencing based mutational analysis for hematologic neoplasms in a CLIA-certified laboratory.
- Differential impact of additional chromosomal abnormalities in myeloid vs lymphoid blast phase of chronic myelogenous Leukemia in the era of tyrosine kinase inhibitor ...
- Prognostic Factors of Hepatosplenic T-cell Lymphoma: Clinicopathologic Study of 28 Cases.
- Myeloid neoplasms with isolated isochromosome 17q demonstrate a high frequency of mutations in SETBP1, SRSF2, ASXL1 and NRAS.
- The clinical significance of 8q24/MYC rearrangement in chronic lymphocytic Leukemia.
Schools
Univ Of Ma Med Sch
University Mass Med Center
New Eng Deaconess Hospital
Stanford University Med Center
Conditions Treated
- Acute Leukemia
- Anemia
- Chronic Myeloid Leukemia (CML)
- Hodgkin's Disease
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Doctors Specialties
- Hematology
- Hematopathology
- Pathology
Accepted Insurances
Education
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National Institutes of Health Clinical Center -
Massachusetts General Hospital -
Stanford University -
Beth Israel Deaconess Medical Center -
University of Massachusetts -
University of Massachusetts Medical School
Hospital
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University of Texas M.D. Anderson Cancer Center
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1609979335 |
| Last Name Of The Provider | MEDEIROS |
| First Name Of The Provider | LEONARD |
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