Associate Professor of Neurology, University Pennsylvania
Neurology
Dr. Leo F. McCluskey, MD
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Leo F. McCluskey, MD is an expert in the field of Neurology. He studied medicine at Columbia University College of Physicians & Surgeons. Columbia University College of Physicians & Surgeons is a top medical university. Columbia University College of Physicians & Surgeons is ranked 8 in research and 52 in primary care medicine He received awards:"CMS Meaningful Use Stage 1 Certification". McCluskey is a published doctor and has 91 publications published. The lastest was: 'Compression and entrapment neuropathies of the lower extremity.' He accepts Medicare.
Publications
- Exome sequencing in amyotrophic lateral Sclerosis identifies risk genes and pathways.
- C9orf72 promoter hypermethylation is neuroprotective: Neuroimaging and neuropathologic evidence.
- Impaired Cognitive Flexibility in Amyotrophic Lateral Sclerosis.
- Hypermethylation of repeat expanded C9orf72 is a clinical and molecular Disease modifier.
- ALS-Plus Syndrome: Non-pyramidal features in a large ALS cohort.
- A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank.
- TDP-43 pathology and neuronal loss in amyotrophic lateral Sclerosis spinal cord.
- Action verb comprehension in amyotrophic lateral sclerosis and Parkinson's Disease.
- TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.
- Phosphorylated Tau as a Candidate Biomarker for Amyotrophic Lateral Sclerosis.
- Genetic and neuroanatomic associations in sporadic frontotemporal lobar degeneration.
- Topography of FUS pathology distinguishes late-onset BIBD from aFTLD-U.
- Stages of pTDP-43 pathology in amyotrophic lateral Sclerosis.
- Deciphering amyotrophic lateral Sclerosis: What phenotype, neuropathology and genetics are telling us about pathogenesis.
- Whole-Brain Analysis of Amyotrophic Lateral Sclerosis by Using Echo-Planar Spectroscopic Imaging.
- Cognitive decline and reduced survival in C9orf72 expansion frontotemporal degeneration and amyotrophic lateral Sclerosis.
- Plasma multianalyte profiling in mild cognitive impairment and Alzheimer Disease.
- Frontal lobe abnormalities on MRS correlate with poor letter fluency in ALS.
- Microglial activation correlates with Disease progression and upper motor neuron clinical symptoms in amyotrophic lateral sclerosis.
- Predictors of emergent feeding tubes and tracheostomies in amyotrophic lateral Sclerosis (ALS).
- Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion.
- Amyotrophic lateral sclerosis-plus Syndrome with TAR DNA-binding protein-43 pathology.
- Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in Brain but not in spinal cord of frontotemporal lobar degeneration and amyotr...
- High-dimensional spatial normalization of diffusion tensor images improves the detection of white matter differences: an example study using amyotrophic lateral sclero...
- TDP-43 pathologic lesions and clinical phenotype in frontotemporal lobar degeneration with ubiquitin-positive inclusions.
- Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral Sclerosis.
- Amyotrophic lateral Sclerosis: diffusion-tensor and chemical shift MR imaging at 3.0 T.
- Camptocormia: pathogenesis, classification, and response to therapy.
- Nocturnal oximetry: utility in the respiratory management of amyotrophic lateral Sclerosis.
- Linear Associations between Clinically Assessed Upper Motor Neuron Disease and Diffusion Tensor Imaging Metrics in Amyotrophic Lateral Sclerosis.
- Ethical issues in states of impaired communication with intact consciousness and language.
- Palliative rehabilitation and amyotrophic lateral Sclerosis: a perfect match.
- Retinal findings in Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (cadasil).
- Amyotrophic lateral Sclerosis: ethical challenges.
- The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration.
- Suprascapular Neuropathy related to a glenohumeral joint cyst.
- Conduction block in vasculitic Neuropathy.
- PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats.
- Exome sequencing reveals VCP mutations as a cause of familial ALS.
- Occupational and sport related Traumatic neuropathy.
- Management of oropharyngeal and tracheobronchial secretions in patients with neurologic Disease.
- Amyotrophic Lateral Sclerosis: ethical issues from diagnosis to end of life.
- Psychological morbidity in ALS: the importance of psychological assessment beyond depression alone.
- Design of comprehensive Alzheimer's Disease centers to address unmet national needs.
- Building an integrated neurodegenerative Disease database at an academic health center.
- Diagnostic and therapeutic methods in the management of dysphagia in the ALS population: issues in efficacy for the out-patient setting.
- Palliative care in amyotrophic lateral sclerosis, Parkinson's Disease, and multiple sclerosis.
- Plasma epidermal growth factor levels predict cognitive decline in Parkinson Disease.
- A cost comparison of hospice care in amyotrophic lateral Sclerosis and lung cancer.
- Cross-sectional evaluation of clinical neuro-ophthalmic abnormalities in an amyotrophic lateral Sclerosis population.
- Evidence of multisystem disorder in whole-Brain map of pathological TDP-43 in amyotrophic lateral sclerosis.
- Medicare hospice referral criteria for patients with amyotrophic lateral Sclerosis: a need for improvement.
- Microglial activation and TDP-43 pathology correlate with executive dysfunction in amyotrophic lateral Sclerosis.
- A yeast functional screen predicts new candidate ALS Disease genes.
- Breaking the news: a survey of ALS patients and their caregivers.
- "Pseudo-conduction block" in vasculitic Neuropathy.
- Postural change of forced vital capacity predicts some respiratory symptoms in ALS.
- Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.
- Multiple pathologies in a patient with a progressive neurodegenerative Syndrome.
- The ALSSQOL: balancing physical and nonphysical factors in assessing quality of life in ALS.
- Novel CSF biomarkers for Alzheimer''s Disease and mild cognitive impairment.
- Gastrostomy insertion in ALS patients with low vital capacity: respiratory support and survival.
- TARDBP mutations in amyotrophic lateral Sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis.
- Motor neuron Disease and frontotemporal lobar degeneration: a tale of two disorders linked to TDP-43.
- Clinical and pathological continuum of multisystem TDP-43 proteinopathies.
- Longitudinal cortical atrophy in amyotrophic lateral sclerosis with frontotemporal Dementia.
- Biomarker discovery for Alzheimer''s Disease, frontotemporal lobar degeneration, and Parkinson''s Disease.
- Novel CSF biomarkers for frontotemporal lobar degenerations.
- Risk genotypes at TMEM106B are associated with cognitive impairment in amyotrophic lateral Sclerosis.
- Survival profiles of patients with frontotemporal dementia and motor neuron Disease.
- Impaired action knowledge in amyotrophic lateral Sclerosis.
- Compression and entrapment neuropathies of the lower extremity.
- Absence of electromyographically detectable acute neuroMuscular transmission defects after intraMuscular interferon-gamma administration.
- Direct muscle stimulation in acute quadriplegic myopathy.
- Anomalous superficial radial sensory innervation of the ulnar dorsum of the hand: a cause of "paradoxical" preservation of ulnar sensory function.
- Recurrent Migraine and intravenous immune globulin therapy.
- Unusual presentation of cis-platinum Neuropathy.
- Cerebral vasculopathy and infarction in a woman with carcinomatous meningitis.
- Evolution of temporal lobe hypoperfusion in transient global amnesia: a serial single photon emission computed tomography study.
- Proximal diabetic Neuropathy presenting with respiratory weakness.
- Venous Thrombosis in an ALS population over four years.
- Diffusion tensor imaging in amyotrophic lateral Sclerosis: volumetric analysis of the corticospinal tract.
- Subcutaneous IGF-1 is not beneficial in 2-year ALS trial.
- Cognitive functioning in sporadic amyotrophic lateral Sclerosis: a six month longitudinal study.
- Phase II screening trial of lithium carbonate in amyotrophic lateral Sclerosis: examining a more efficient trial design.
- Motor neuron Disease clinically limited to the lower motor neuron is a diffuse TDP-43 proteinopathy.
- Establishment of a cell model of ALS Disease: Golgi apparatus disruption occurs independently from apoptosis.
- Efficacy of minocycline in patients with amyotrophic lateral Sclerosis: a phase III randomised trial.
- A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS.
- Quantitative proton magnetic resonance spectroscopy detects abnormalities in dorsolateral prefrontal cortex and motor cortex of patients with frontotemporal lobar dege...
Schools
Columbia University College Of Physicians and Surgeons
University Of Michigan
Hospital Of The University Of Pennsylvania
Procedures Preformed
- EEG (Electroencephalogram)
- EMG (Electromyography)
Conditions Treated
- Alzheimer's Disease
- Anterior Horn Disease
- Ataxia
- Autonomic Disorders
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Doctors Specialties
- Clinical Neurophysiology
- Neurology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
Education
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University of Pennsylvania Health System -
University of Michigan Hospitals and Health Centers -
Columbia University College of Physicians & Surgeons
Hospital
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Hospital of the University of Pennsylvania -
Pennsylvania Hospital
Drug Facts
| NPI NUMBER | 1902837792 | |
| NPPES Provider LastName | MCCLUSKEY | |
| NPPES Provider FirstName | LEO | |
| NPPES Provider ZIPCode | 191076130 | |
| NPPES Provider State | PA | |
| Specialty Description | Neurology | |
| Total Claim Count | 942.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 11.0 | |
| Percent Opioid Claims | 1.17 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1902837792 |
| Last Name Of The Provider | MCCLUSKEY |
| First Name Of The Provider | LEO |
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