Professor, Internal Medicine, University of Virginia School of Medicine
Cardiology
Dr. Lawrence W. Gimple, MD
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Lawrence W. Gimple is an expert in the field of Cardiology. He went to Harvard Medical School. Harvard Medical School is a top medical college. Harvard Medical School is ranked 1 in research and 12 in primary care medicine He received 3 awards: "Regional Top Doctor", "CMS Meaningful Use Stage 1 Certification" and "Fellow (FACC)". Doctor Lawrence W. Gimple, MD is a published doctor. He published 68 publications, including: 'Effectiveness of heparin in preventing thrombin generation and thrombin activity in patients undergoing coronary intervention.' Lawrence Gimple accepts all Medicare patients.
Publications
- Plasma chemokine levels are associated with the presence and extent of angiographic coronary collaterals in chronic ischemic heart disease.
- Coronary angiography is a better predictor of mortality than noninvasive testing in patients evaluated for renal transplantation.
- Comparison between angiography and fractional flow reserve versus single-photon emission computed tomographic myocardial perfusion imaging for determining lesion signi...
- High left ventricular mass index does not limit the utility of fractional flow reserve for the physiologic assessment of lesion severity.
- Outcome of patients with acute coronary syndromes and moderate coronary lesions undergoing deferral of revascularization based on fractional flow reserve assessment.
- Prevalence of unfavorable angiographic characteristics for percutaneous intervention in patients with unprotected left main coronary artery disease.
- Coronary flow reserve abnormalities in patients with diabetes mellitus who have end-stage renal disease and normal epicardial coronary arteries.
- Effect of acute myocardial infarction on the utility of fractional flow reserve for the physiologic assessment of the severity of coronary artery narrowing.
- Percutaneous treatment of focal vs. diffuse in-stent restenosis: a prospective randomized comparison of conventional therapies.
- Comparison between visual assessment and quantitative angiography versus fractional flow reserve for native coronary narrowings of moderate severity.
- Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model.
- Selective alpha(v)beta(3)-receptor blockade reduces macrophage infiltration and restenosis after balloon angioplasty in the atherosclerotic rabbit.
- Relationship between extent of residual myocardial viability and coronary flow reserve in patients with recent myocardial infarction.
- Quantification of mitral regurgitation in the cardiac catheterization laboratory with contrast echocardiography.
- All-trans-retinoic acid limits restenosis after balloon angioplasty in the focally atherosclerotic rabbit : a favorable effect on vessel remodeling.
- Arterial injury increases expression of inflammatory adhesion molecules in the carotid arteries of apolipoprotein-E-deficient mice.
- Local adenovirus-mediated delivery of hirudin in a rabbit arterial injury model.
- Angiographic findings in patients undergoing catheterization for recurrent symptoms within 30 days of successful coronary intervention.
- Usefulness of subcutaneous low molecular weight heparin (ardeparin) for reduction of restenosis after percutaneous transluminal coronary angioplasty.
- Effectiveness of heparin in preventing thrombin generation and thrombin activity in patients undergoing coronary intervention.
- Early plus delayed hirudin reduces restenosis in the atherosclerotic rabbit more than early administration alone: potential implications for dosing of antithrombin age...
- Hirudin reduces tissue factor expression in neointima after balloon injury in rabbit femoral and porcine coronary arteries.
- Effectiveness of percutaneous coronary interventions to prevent recurrent coronary events in patients on chronic hemodialysis.
- Predictors of luminal narrowing by neointima after angioplasty in atherosclerotic rabbits.
- Assessing prognosis after acute myocardial infarction in the thrombolytic era.
- Myocardial viability in patients with chronic coronary artery disease and previous myocardial infarction: comparison of myocardial contrast echocardiography and myocar...
- Improved outcome after coronary bypass surgery in patients with ischemic cardiomyopathy and residual myocardial viability.
- A new single-injury model of balloon angioplasty in cholesterol-fed rabbits: beneficial effect of hirudin and comparison with double-injury model.
- alpha-Thrombin induces transforming growth factor-beta1 mRNA and protein in cultured vascular smooth muscle cells via a proteolytically activated receptor.
- Remodeling rather than neointimal formation?
- Arterial thrombin activity after angioplasty in an atherosclerotic rabbit model: time course and effect of hirudin.
- Myocardial contrast echocardiography demonstrates that collateral flow can preserve myocardial function beyond a chronically occluded coronary artery.
- Thrombin and vascular smooth muscle cell proliferation: implications for atherosclerosis and restenosis.
- Paraneoplastic encephalomyeloneuritis obscured by coma.
- Relation between air-filled albumin microbubble and red blood cell rheology in the human myocardium. Influence of echocardiographic systems and chest wall attenuation.
- Effectiveness of hirulog in reducing restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits.
- Effect of thrombin inhibition with desulfatohirudin on early kinetics of cellular proliferation after balloon angioplasty in atherosclerotic rabbits.
- Bolus intravenous nitroglycerin predominantly reduces afterload in patients with excessive arterial elastance.
- Exercise thallium-201 scintigraphy after thrombolytic therapy with or without angioplasty for acute myocardial infarction.
- Quantitative planar rest-redistribution 201Tl imaging in detection of myocardial viability and prediction of improvement in left ventricular function after coronary by...
- Percutaneous balloon pericardiotomy for the treatment of cardiac tamponade and large pericardial effusions: description of technique and report of the first 50 cases.
- Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor.
- Successful preoperative diagnosis and treatment of a saphenous vein coronary artery bypass graft aneurysm.
- Platelet activation during coronary angioplasty in humans.
- Thrombin-induced mitogenesis of vascular SMC is partially mediated by autocrine production of PDGF-AA.
- Intracoronary angiotensin-converting enzyme inhibition improves diastolic function in patients with hypertensive left ventricular hypertrophy.
- Microvascular integrity indicates myocellular viability in patients with recent myocardial infarction. New insights using myocardial contrast echocardiography.
- Starr-Edwards valve thrombosis detected preoperatively by transesophageal echocardiography.
- Response of femoral arteries of cholesterol-fed rabbits to balloon angioplasty with or without laser: emphasis on the distribution of foam cells.
- Specific factor Xa inhibition reduces restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits.
- Why do patients with congestive heart failure tolerate the initiation of beta-blocker therapy?
- Myocardial viability. Assessment by cardiac scintigraphy.
- Geometric remodeling is not the principal pathogenetic process in restenosis after balloon angioplasty. Evidence from correlative angiographic-histomorphometric studie...
- Elevated serum lipoprotein(a) is a risk factor for clinical recurrence after coronary balloon angioplasty.
- Identification of viable myocardium with contrast echocardiography in patients with poor left ventricular systolic function caused by recent or remote myocardial infar...
- Effect of midinfrared holmium: YAG laser angioplasty with and without balloon angioplasty on acute outcome and restenosis in atherosclerotic femoral arteries in rabbits.
- Thrombin-induced mitogenesis in cultured aortic smooth muscle cells requires prolonged thrombin exposure.
- Prevention of coronary artery reocclusion and reduction in late coronary artery stenosis after thrombolytic therapy in patients with acute myocardial infarction. A ran...
- Prognostic utility of predischarge dipyridamole-thallium imaging compared to predischarge submaximal exercise electrocardiography and maximal exercise thallium imaging...
- Correlation between template bleeding times and spontaneous bleeding during treatment of acute myocardial infarction with recombinant tissue-type plasminogen activator.
- Pharmacodynamic study of F(ab')2 fragments of murine monoclonal antibody 7E3 directed against human platelet glycoprotein IIb/IIIa in patients with unstable angina pec...
- Effectiveness of recombinant desulphatohirudin in reducing restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits.
- On-line intraoperative quantitation of regional myocardial perfusion during coronary artery bypass graft operations with myocardial contrast two-dimensional echocardio...
- Myocardial thallium-201 scintigraphy for assessment of viability in patients with severe left ventricular dysfunction.
- Effect of chronic subcutaneous or intramural administration of heparin on femoral artery restenosis after balloon angioplasty in hypercholesterolemic rabbits. A quanti...
- Extent and severity of coronary disease and mortality in patients with end-stage renal failure evaluated for renal transplantation.
- Fractional flow reserve of infarct-related arteries identifies reversible defects on noninvasive myocardial perfusion imaging early after myocardial infarction.
Schools
Harvard Medical School
Massachusetts General Hospital
Mass Genl HospHarvard
Procedures Preformed
- Ablation for Treatment of Cardiac Arrhythmias
- Cardiac Catheterization (incl. Coronary Angiography)
- Cardiac Imaging
- Cardiac MRI (Magnetic Resonance Imaging) of Heart or Chest
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Doctors Specialties
- Cardiology
- Interventional Cardiology
Accepted Insurances
Awards
- Regional Top Doctor
- CMS Meaningful Use Stage 1 Certification
- Fellow (FACC)
Education
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Massachusetts General Hospital -
Harvard Medical School
Hospital
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University of Virginia Medical Center
Drug Facts
| NPI NUMBER | 1871659581 | |
| NPPES Provider LastName | GIMPLE | |
| NPPES Provider FirstName | LAWRENCE | |
| NPPES Provider ZIPCode | 229080001 | |
| NPPES Provider State | VA | |
| Specialty Description | Cardiology | |
| Total Claim Count | 343.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1871659581 |
| Last Name Of The Provider | GIMPLE |
| First Name Of The Provider | LAWRENCE |
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