Professor of Medicine, Boston University
Hematology
Dr. Kevan L. Hartshorn, MD
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Kevan L. Hartshorn works in the field of Hematology. He went to Albert Einstein College of Medicine of Yeshiva University. He received awards:"Boston Magazine". Kevan Hartshorn has written publications. He has 99 publications published with PubMed. The lastest paper is: 'Failure of oral nitrate and calcium channel blocker therapy to prevent 5-fluorouracil-related myocardial ischemia: a case report.' He accepts Medicare payments and is registered with Medicare.gov.
Publications
- LL-37 modulates human neutrophil responses to influenza A virus.
- Does a Personal or Family History of Malignancy Preclude the Use of Immunomodulators and Biologics in IBD.
- Mutations flanking the carbohydrate binding site of surfactant protein D confer antiviral activity for pandemic influenza A viruses.
- Recombinant human mannose-binding lectin dampens human alveolar macrophage inflammatory responses to influenza A virus in vitro.
- Efficacy of recombinant chimeric lectins, consisting of mannose binding lectin and L-ficolin, against influenza A viral infection in mouse model study.
- Molecular mechanisms of inhibition of influenza by surfactant protein d revealed by large-scale molecular dynamics simulation.
- The amazing innate Immune response to influenza A virus infection.
- Why Does Pandemic Influenza Virus Kill?
- FABP5 deficiency enhances susceptibility to H1N1 influenza A virus-induced Lung inflammation.
- Comparative glycomics of leukocyte glycosaminoglycans.
- Disparity in the use of combined modality therapy for rectal Cancer in the older adult.
- The human cathelicidin LL-37 inhibits influenza A viruses through a mechanism distinct from that of surfactant protein D or defensins.
- Randomized Controlled Trial of a Video Decision Support Tool for Cardiopulmonary Resuscitation Decision Making in Advanced Cancer.
- Mannose-binding lectin binds to amyloid β protein and modulates inflammation.
- Mutagenesis of Surfactant Protein D Informed by Evolution and X-ray Crystallography Enhances Defenses against Influenza A Virus in Vivo.
- GM-CSF modulates pulmonary resistance to influenza A infection.
- Critical Role of SerpinB1 in Regulating Inflammatory Responses in Pulmonary Influenza Infection.
- IntroDuction of N-linked glycans in the lectin domain of surfactant protein D (SP-D): impact on interactions with influenza A viruses.
- The ability of pandemic influenza virus hemagglutinins to induce lower respiratory pathology is associated with decreased surfactant protein D binding.
- Monoclonal antibody-assisted structure-function Analysis of the carbohydrate recognition domain of surfactant protein D.
- New look at an old problem: bacterial superinfection after influenza.
- Human defensins and LL-37 in mucosal immunity.
- Viral aggregating and opsonizing activity in collectin trimers.
- Role of surfactant protein A and D (SP-A and SP-D) in human antiviral host defense.
- Review: Defensins and cathelicidins in Lung immunity.
- Review: Structural determinants of pattern recognition by Lung collectins.
- Interactions of alpha-, beta-, and theta-defensins with influenza A virus and surfactant protein D.
- Differentiated human alveolar type II cells secrete antiviral IL-29 (IFN-lambda 1) in response to influenza A infection.
- Innate immunity to influenza virus: implications for future therapy.
- Impact of neutrophils on antiviral activity of human bronchoalveolar lavage fluid.
- Human neutrophil defensins increase neutrophil uptake of influenza A virus and bacteria and modify virus-induced respiratory burst responses.
- Innate defense against influenza A virus: activity of human neutrophil defensins and interactions of defensins with surfactant protein D.
- Respiratory innate Immune proteins differentially modulate the neutrophil respiratory burst response to influenza A virus.
- Cooperative anti-influenza activities of respiratory innate Immune proteins and neuraminidase inhibitor.
- Interactions of influenza A virus with sialic acids present on porcine surfactant protein D.
- Effective targeting of pathogens to neutrophils via chimeric surfactant protein D/anti-CD89 protein.
- Tetranectin Binds to the Kringle 1-4 Form of Angiostatin and Modifies Its Functional Activity.
- Lung and salivary scavenger receptor glycoprotein-340 contribute to the host defense against influenza A viruses.
- Porcine pulmonary collectins show distinct interactions with influenza A viruses: role of the N-linked oligosaccharides in the carbohydrate recognition domain.
- Contributions of the N- and C-terminal domains of surfactant protein d to the binding, aggregation, and phagocytic uptake of bacteria.
- Complementation of pulmonary abnormalities in SP-D(-/-) mice with an SP-D/conglutinin fusion protein.
- Porcine surfactant protein D is N-glycosylated in its carbohydrate recognition domain and is assembled into differently charged oligomers.
- Contemporary avian influenza a virus subtype h1, h6, h7, h10, and h15 hemagglutinin genes encode a Mammalian virulence factor similar to the 1918 pandemic virus h1 hem...
- Alzheimer's associated beta-amyloid protein inhibits influenza A virus and modulates viral interactions with phagocytes.
- A reapplication of the process scoring System for dreams.
- Brief report: improvements in the behavior of children with autism following massage therapy.
- Long-term maintenance of infant memory.
- The ontogeny of long-term memory over the first year-and-a-half of life.
- Collectins and pulmonary innate immunity.
- Circulating neutrophil CD18 receptor expression and ischemic flap neutrophil infiltration in a guinea pig model.
- Therapeutic perspectives in human immunodeficiency virus infection.
- Infant learning and long-term memory at 6 months: a confirming Analysis.
- Interactions of recombinant human pulmonary surfactant protein D and SP-D multimers with influenza A.
- Site-directed mutagenesis of Cys-15 and Cys-20 of pulmonary surfactant protein D. Expression of a trimeric protein with altered anti-viral properties.
- Partial purification and identification of an immunosuppressive factor in AIDS sera.
- In vivo correlation of neutrophil receptor expression, ischemia-reperfusion injury, and selective 5-lipoxygenase inhibition in guinea pigs.
- An expanding training series proTracts retention for 3-month-old infants.
- Systemic neutrophil intrinsic 5-lipoxygenase activity and CD18 receptor expression linked to reperfusion injury.
- Developmental changes in the specificity of memory over the first year of life.
- Increasing antiviral activity of surfactant protein d trimers by introducing residues from bovine serum collectins: dissociation of mannan-binding and antiviral activity.
- Multiple components contribute to ability of saliva to inhibit influenza viruses.
- Inhibition of influenza viral neuraminidase activity by collectins.
- Pulmonary surfactant proteins A and D enhance neutrophil uptake of bacteria.
- Human mannose-binding protein functions as an opsonin for influenza A viruses.
- Antibody-dependent cell-mediated cytotoxicity against cells infected with the human immunodeficiency virus.
- Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon.
- Neutrophil deactivation by influenza A viruses: mechanisms of protection after viral opsonization with collectins and hemagglutination-inhibiting antibodies.
- Conglutinin acts as an opsonin for influenza A viruses.
- Bovine conglutinin gene exon structure reveals its evolutionary relationship to surfactant protein-D.
- Bovine conglutinin (BC) mRNA expressed in Liver: cloning and characterization of the BC cDNA reveals strong homology to surfactant protein-D.
- Evidence for a protective role of pulmonary surfactant protein D (SP-D) against influenza A viruses.
- Human neutrophil respiratory burst response to influenza A virus occurs at an intracellular location.
- Interferon-alpha enhances neutrophil respiratory burst responses to stimulation with influenza A virus and FMLP.
- Neutrophil deactivation by influenza A virus. Role of hemagglutinin binding to specific sialic acid-bearing cellular proteins.
- Dot immunobinding assay for detection of human immunodeficiency virus-associated antigens.
- Effects of influenza A virus on human neutrophil calcium metabolism.
- Activity of interferons alpha, beta, and gamma against human immunodeficiency virus replication in vitro.
- Synergistic inhibition of human T-cell lymphotropic virus type III replication in vitro by phosphonoformate and recombinant alpha-A interferon.
- Recombinant human interferon alfa-A suppresses HTLV-III replication in vitro.
- Parameters of neutrophil activation: models of priming and deactivation.
- Priming of human neutrophils with N-formyl-methionyl-leucyl-phenylalanine by a calcium-independent, pertussis toxin-insensitive pathway.
- The influenza virus--infected phagocyte. A model of deactivation.
- Ribavirin antagonizes the effect of azidothymidine on HIV replication.
- Detection of human T-cell lymphotropic virus type III-related antigens and anti-human T-cell lymphotropic virus type III antibodies by anticomplementary immunofluoresc...
- Influenza A virus and the neutrophil: a model of natural immunity.
- Effect of nisoldipine on priming and activation of the human neutrophil respiratory burst.
- Characterization of influenza A virus activation of the human neutrophil.
- Human neutrophil stimulation by influenza virus: relationship of cytoplasmic pH changes to cell activation.
- Influenza A virus binding to human neutrophils and cross-linking requirements for activation.
- Anomalous features of human neutrophil activation by influenza A virus are shared by related viruses and sialic acid-binding lectins.
- Comparison of influenza A virus and formyl-methionyl-leucyl-phenylalanine activation of the human neutrophil.
- Enhanced anti-influenza activity of a surfactant protein D and serum conglutinin fusion protein.
- Mechanisms of anti-influenza activity of surfactant proteins A and D: comparison with serum collectins.
- Influenza A virus up-regulates neutrophil adhesion molecules and adhesion to biological surfaces.
- Influenza A virus accelerates neutrophil apoptosis and markedly potentiates apoptotic effects of bacteria.
- Failure of Oral nitrate and calcium channel blocker therapy to prevent 5-fluorouracil-related myocardial ischemia: a case report.
- Prophylaxis and treatment of influenza virus infection.
- Neutrophil survival is markedly reduced by incubation with influenza virus and Streptococcus pneumoniae: role of respiratory burst.
Schools
Albert Einstein College of Medicine of Yeshiva University
Boston City Hospital
Ma Genl Hospital
Procedures Preformed
- Thoracentesis
Conditions Treated
- Acute Leukemia
- Adrenal Gland Cancer
- Anal and Rectal Cancer
- Anemia
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Doctors Specialties
- Hematology
- Medical Oncology
- Oncology
Accepted Insurances
Awards
- Boston Magazine
Education
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Massachusetts General Hospital -
Boston University Medical Center -
Albert Einstein College of Medicine of Yeshiva University
Hospital
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Boston Medical Center
Drug Facts
| NPI NUMBER | 1700862745 | |
| NPPES Provider LastName | HARTSHORN | |
| NPPES Provider FirstName | KEVAN | |
| NPPES Provider ZIPCode | 021182905 | |
| NPPES Provider State | MA | |
| Specialty Description | Hematology/Oncology | |
| Total Claim Count | 183.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 26.0 | |
| Percent Opioid Claims | 14.21 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1700862745 |
| Last Name Of The Provider | HARTSHORN |
| First Name Of The Provider | KEVAN |
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