Professor, Neurology, Mayo Medical School
Neurology
Dr. Keith A. Josephs, MD
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Dr. Keith A. Josephs is an expert in the field of Neurology. Keith Josephs is also published. He has 98 publications published. The lastest publication: "Cerebellar ataxia in progressive supranuclear palsy: An autopsy study of PSP-C.' He accepts Medicare.
Publications
- Mixed tau and TDP-43 pathology in a patient with unclassifiable primary Progressive aphasia.
- Regional β-amyloid burden does not correlate with cognitive or language deficits in Alzheimer's Disease presenting as aphasia.
- Progressive supranuclear palsy: progression and survival.
- Cerebellar Ataxia in progressive supranuclear palsy: An autopsy study of PSP-C.
- Globular Glial Tauopathy Presenting as Semantic Variant Primary Progressive Aphasia.
- Characterizing White Matter Tract Degeneration in Syndromic Variants of Alzheimer's Disease: A Diffusion Tensor Imaging Study.
- Working memory and language network dysfunctions in logopenic aphasia: a task-free fMRI comparison with Alzheimer's Dementia.
- Clinical and neuroimaging biomarkers of amyloid-negative logopenic primary Progressive aphasia.
- Microbleeds in Atypical Presentations of Alzheimer's Disease: A Comparison to Dementia of the Alzheimer's Type.
- Brain atrophy over time in genetic and sporadic frontotemporal Dementia: a study of 198 serial magnetic resonance images.
- The evolution of primary Progressive apraxia of speech.
- Frontotemporal Dementia and its subtypes: a genome-wide association study.
- APOE ε4 influences β-amyloid deposition in primary Progressive aphasia and speech apraxia.
- Ataxin-2 as potential Disease modifier in C9ORF72 expansion carriers.
- TDP-43 in Alzheimer's Disease is not associated with clinical FTLD or Parkinsonism.
- TDP-43 is a key player in the clinical features associated with Alzheimer's Disease.
- Improved DTI registration allows voxel-based analysis that outperforms Tract-Based Spatial Statistics.
- Diffusion tensor imaging comparison of Progressive supranuclear palsy and corticobasal syndromes.
- FDG-PET in pathologically confirmed spontaneous 4R-tauopathy variants.
- The neuroanatomy of pure apraxia of speech in Stroke.
- Progranulin-associated PiB-negative logopenic primary Progressive aphasia.
- TMEM106B protects C9ORF72 expansion carriers against frontotemporal Dementia.
- Amyloid burden correlates with cognitive decline in Alzheimer's Disease presenting with aphasia.
- The pimple sign of Progressive supranuclear palsy syndrome.
- Staging TDP-43 pathology in Alzheimer's Disease.
- Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration.
- Parkinsonian features in hereditary diffuse leukoencephalopathy with spheroids (HDLS) and CSF1R mutations.
- Midbrain atrophy is not a biomarker of Progressive supranuclear palsy pathology.
- Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study.
- Primary Progressive aphasia and apraxia of speech.
- Neurocognitive speed associates with frontotemporal lobar degeneration TDP-43 subtypes.
- Clinical and imaging characterization of Progressive spastic dysarthria.
- Aphasia with left occipitotemporal hypometabolism: A novel presentation of posterior cortical atrophy?
- Elevated occipital β-amyloid deposition is associated with widespread cognitive impairment in logopenic Progressive aphasia.
- Occupational Differences Between Alzheimer's and Aphasic Dementias: Implication for Teachers.
- Profilin-1 mutations are rare in patients with amyotrophic lateral sclerosis and frontotemporal Dementia.
- Pallidonigroluysian atrophy associated with p.A152T variant in MAPT.
- Mutations in protein N-arginine methyltransferases are not the cause of FTLD-FUS.
- Neuropsychiatry of corticobasal degeneration and Progressive supranuclear palsy.
- The alien limb phenomenon.
- Modeling trajectories of regional volume loss in Progressive supranuclear palsy.
- Identification of an atypical variant of logopenic Progressive aphasia.
- Microbleeds in the logopenic variant of primary Progressive aphasia.
- Neuroimaging comparison of primary Progressive apraxia of speech and Progressive supranuclear palsy.
- Distinct regional anatomic and functional correlates of neurodegenerative apraxia of speech and aphasia: An MRI and FDG-PET study.
- Quantitative neurofibrillary tangle density and brain volumetric MRI analyses in Alzheimer's Disease presenting as logopenic progressive aphasia.
- Corticospinal tract degeneration associated with TDP-43 type C pathology and semantic Dementia.
- Frontal asymmetry in behavioral variant frontotemporal Dementia: clinicoimaging and pathogenetic correlates.
- Criteria for the diagnosis of corticobasal degeneration.
- Ideomotor apraxia in agrammatic and logopenic variants of primary Progressive aphasia.
- Neuroanatomical correlates of the Progressive supranuclear palsy corticobasal syndrome hybrid.
- Clinical and electrophysiologic variability in amyotrophic lateral sclerosis within a kindred harboring the C9ORF72 repeat expansion.
- Characterizing a neurodegenerative syndrome: primary Progressive apraxia of speech.
- Primary lateral sclerosis as Progressive supranuclear palsy: Diagnosis by diffusion tensor imaging.
- Imaging measures predict progression in Progressive supranuclear palsy.
- Autopsy-proven progressive supranuclear palsy presenting as behavioral variant frontotemporal Dementia.
- Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion in C9ORF72.
- Rates of brain atrophy and clinical decline over 6 and 12-month intervals in PSP: Determining sample size for treatment trials.
- Right temporal variant frontotemporal dementia with motor neuron Disease.
- Altered microRNA expression in frontotemporal lobar degeneration with TDP-43 pathology caused by progranulin mutations.
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS.
- Neuropathological features of corticobasal degeneration presenting as corticobasal syndrome or Richardson syndrome.
- Parkinsonism and dropped head: Dystonia, myopathy or both?
- Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal Dementia.
- Deep brain stimulation in benign tremulous parkinsonism.
- Neuropathology of Frontotemporal Lobar Degeneration-Tau (FTLD-Tau).
- Novel pathogenic mutations and copy number variations in the VPS13A Gene in patients with chorea-acanthocytosis.
- Steroid-responsive encephalopathy subsequently associated with Alzheimer Disease pathology: A case series.
- Disrupted thalamocortical connectivity in PSP: A resting-state fMRI, DTI, and VBM study.
- Clinical correlates of white matter tract degeneration in Progressive supranuclear palsy.
- Sleep manifestations of voltage-gated potassium channel complex autoimmunity.
- Neuropathological background of phenotypical variability in frontotemporal Dementia.
- Imaging Signatures of Molecular Pathology in Behavioral Variant Frontotemporal Dementia.
- Psychoses as the presenting manifestation of Creutzfeldt-Jakob Disease in an elderly male.
- Incidental Lewy body Disease: Do some cases represent a preclinical stage of dementia with Lewy bodies?
- Neuronal intranuclear inclusion Disease: No longer a pain in the butt.
- Antemortem differential diagnosis of Dementia pathology using structural MRI: Differential-STAND.
- Ifosfamide associated myoclonus-encephalopathy syndrome.
- Sporadic corticobasal syndrome with progranulin mutation presenting as Progressive apraxic agraphia.
- Gray matter correlates of behavioral severity in Progressive supranuclear palsy.
- Autoimmune Dementia: clinical course and predictors of immunotherapy response.
- Parkinson Disease and down in the dumps: pumped or stumped?
- Anatomical differences between CBS-corticobasal degeneration and CBS-Alzheimer's Disease.
- Fluorodeoxyglucose F18 positron emission tomography in Progressive apraxia of speech and primary Progressive aphasia variants.
- The stripe of primary lateral sclerosis: focal primary motor cortex hypometabolism seen on fluorodeoxyglucose F18 positron emission tomography.
- Temporoparietal atrophy: A marker of AD pathology independent of clinical diagnosis.
- Survival profiles of patients with frontotemporal dementia and motor neuron Disease.
- GCH1 in early-onset Parkinson's Disease.
- Comparison of risk factor profiles in incidental Lewy body Disease and Parkinson Disease.
- Alzheimer's Disease and corticobasal degeneration presenting as corticobasal syndrome.
- The clinical spectrum of stereotypies in frontotemporal lobar degeneration.
- Pramipexole induced compulsive behaviors abate after initiation of rotigitine.
- Prominent phenotypic variability associated with mutations in Progranulin.
- Voxel-based morphometry patterns of atrophy in FTLD with mutations in MAPT or PGRN.
- Rapidly progressive young-onset Dementia.
- Rapidly progressive neurodegenerative Dementias.
- Psychogenic tremor: long-term prognosis in patients with electrophysiologically confirmed Disease.
Schools
Medical College of Pennsylvania
Mayo Clin
Queen Square
Conditions Treated
- Alzheimer's Disease
- Ataxia
- Cerebral Artery Thrombosis
- Convulsions
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Doctors Specialties
- Neurology
Accepted Insurances
Education
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Mayo School of Graduate Medical Education
Hospital
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Mayo Clinic - Rochester, Minnesota
Drug Facts
| NPI NUMBER | 1326011289 | |
| NPPES Provider LastName | JOSEPHS | |
| NPPES Provider FirstName | KEITH | |
| NPPES Provider ZIPCode | 559050001 | |
| NPPES Provider State | MN | |
| Specialty Description | Neurology | |
| Total Claim Count | 43.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1326011289 |
| Last Name Of The Provider | JOSEPHS |
| First Name Of The Provider | KEITH |
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