Professor, Medicine, Economics and Cell and Molecular Medicine, University of Arizona College of Medicine; Co-Director, Center for Management Innovations in Health Care, Eller College of Management
Infectious Disease
Dr. Keith A. Joiner, MD
|
|
Give Review
Doctor Keith A. Joiner, MD works in the field of Infectious Disease. He went to University of Colorado Denver School of Medicine. University of Colorado Denver School of Medicine is a one of the best medicals schools. University of Colorado Denver School of Medicine is ranked 35/8 in Research/PrimaryCare. He received awards:"Elected Member" and "Fellow, Elected". Doctor Keith A. Joiner, MD is a published doctor. He published 101 publications, including: 'Targeted reduction of nucleoside triphosphate hydrolase by antisense RNA inhibits Toxoplasma gondii proliferation.'
Publications
- A review of the economics of adult congenital heart disease.
- Introduction of caveolae structural proteins into the protozoan Toxoplasma results in the formation of heterologous caveolae but not caveolar endocytosis.
- The biologic activity of mast cell granules. IV. The effect of complement depletion on rat cutaneous late phase reactions.
- Supporting research in departments of internal medicine: recommendations for NIH.
- Cell attachment and entry by Toxoplasma gondii.
- Promoting laboratory research during infectious diseases fellowship training or telling the truth about training in clinical research.
- Why do so many surface proteins of trypanosomatids have GPI-anchors?
- An analysis of the Candida albicans genome database for soluble secreted proteins using computer-based prediction algorithms.
- Counterpoint: UNAFs--perspective and prevention.
- Relative efficacy and critical interval of antimicrobial agents in experimental infections involving bacteroides fragilis.
- Serum sensitivity of Neisseria gonorrhoeae: the role of lipopolysaccharide.
- Characterization of protein I from serum-sensitive and serum-resistant transformants of Neisseria gonorrhoeae.
- Dictyostelium discoideum mutants with conditional defects in phagocytosis.
- The human mannose-binding protein functions as an opsonin.
- gp72, the 72 kilodalton glycoprotein, is the membrane acceptor site for C3 on Trypanosoma cruzi epimastigotes.
- Evasion of the alternative complement pathway by metacyclic trypomastigotes of Trypanosoma cruzi: dependence on the developmentally regulated synthesis of surface prot...
- Comparative efficacy of 10 antimicrobial agents in experimental infections with Bacteroides fragilis.
- Evasion of alternative complement pathway by Trypanosoma cruzi results from inefficient binding of factor B.
- Serum-resistant mutants of Escherichia coli O111 contain increased lipopolysaccharide, lack an O antigen-containing capsule, and cover more of their lipid A core with ...
- Studies on the mechanism of bacterial resistance to complement-mediated killing. III. C5b-9 deposits stably on rough and type 7 S. pneumoniae without causing bacterial...
- Developmentally regulated expression by Trypanosoma cruzi of molecules that accelerate the decay of complement C3 convertases.
- The function of antibody and complement in the lysis of bacteria.
- Localization of complement component 3 on Streptococcus pneumoniae: anti-capsular antibody causes complement deposition on the pneumococcal capsule.
- Studies on the mechanism of bacterial resistance to complement-mediated killing. II. C8 and C9 release C5b67 from the surface of Salmonella minnesota S218 because the ...
- Studies on the mechanism of bacterial resistance to complement-mediated killing. I. Terminal complement components are deposited and released from Salmonella minnesota...
- Activation of the alternative complement pathway by blood culture isolates of Bacteroides fragilis.
- Transfer of tetracycline or clindamycin resistance among strains of Bacteroides fragilis in experimental abscesses.
- Classical complement pathway activation by antipneumococcal antibodies leads to covalent binding of C3b to antibody molecules.
- Antibiotic levels in infected and sterile subcutaneous abscesses in mice.
- Mechanism of bacterial resistance to complement-mediated killing: inserted C5b-9 correlates with killing for Escherichia coli O111B4 varying in O-antigen capsule and O...
- A quantitative analysis of C3 binding to O-antigen capsule, lipopolysaccharide, and outer membrane protein of E. coli 0111B4.
- Role of serum in stimulation of polymorphonuclear leukocyte, luminol-dependent chemiluminescence by influenza A.
- C3b binding, but not its breakdown, is affected by the structure of the O-antigen polysaccharide in lipopolysaccharide from Salmonellae.
- Mechanism of action of blocking immunoglobulin G for Neisseria gonorrhoeae.
- Monoclonal antibodies directed against gonococcal protein I vary in bactericidal activity.
- Bactericidal but not nonbactericidal C5b-9 is associated with distinctive outer membrane proteins in Neisseria gonorrhoeae.
- Studies on the mechanism of bacterial resistance to complement-mediated killing and on the mechanism of action of bactericidal antibody.
- IgG bearing covalently bound C3b has enhanced bactericidal activity for Escherichia coli 0111.
- Multimeric complement component C9 is necessary for killing of Escherichia coli J5 by terminal attack complex C5b-9.
- Activated terminal complement in cerebrospinal fluid in Guillain-Barré syndrome and multiple sclerosis.
- Activation of terminal components of complement in patients with Guillain-Barré syndrome and other demyelinating neuropathies.
- Inhibition of endotoxin-induced priming of human neutrophils by lipid X and 3-Aza-lipid X.
- Detection of activated terminal complement (C5b-9) in cerebrospinal fluid from patients with central nervous system involvement of primary Sjogren's syndrome or system...
- Studies of antibody and complement function in host defense against bacterial infection.
- Membrane attack complex of complement in rheumatoid synovial tissue demonstrated by immunofluorescent microscopy.
- Pathogenesis of Campylobacter fetus infections. Failure of encapsulated Campylobacter fetus to bind C3b explains serum and phagocytosis resistance.
- Complement binding by two developmental stages of Leishmania major promastigotes varying in expression of a surface lipophosphoglycan.
- Terminal complement complexes (SC5b-9) in cerebrospinal fluid in autoimmune nervous system diseases.
- Serum complement activation in central nervous system disease in Sjögren's syndrome.
- Mechanisms of stable serum resistance of Neisseria gonorrhoeae.
- Analyses of the immunoaccessibility of H8 antigen and the functionality of H8 specific monoclonal antibody 10.
- Multimeric C9 within C5b-9 is required for inner membrane damage to Escherichia coli J5 during complement killing.
- Interaction of complement with serum-sensitive and serum-resistant strains of Pseudomonas aeruginosa.
- Enhanced invasion of mononuclear phagocytes by serum-treated Trypanosoma cruzi is due to Clq.
- Complement evasion by bacteria and parasites.
- Biochemical characterization of a factor produced by trypomastigotes of Trypanosoma cruzi that accelerates the decay of complement C3 convertases.
- CR1 mediates binding of L. major metacyclic promastigotes to human macrophages.
- A complement-resistant HeLa cell line (T638) is blocked at the step of C3 deposition.
- Complement component C1q enhances invasion of human mononuclear phagocytes and fibroblasts by Trypanosoma cruzi trypomastigotes.
- Multimeric C9 within C5b-9 deposits in unique locations in the cell wall of Salmonella typhimurium.
- Complement evasion by protozoa.
- Lytic rabbit IgG for tissue culture trypomastigotes of Trypanosoma cruzi alters the extent and form of complement deposition.
- Toxoplasma gondii: mechanism of resistance to complement-mediated killing.
- Human mannose-binding protein activates the alternative complement pathway and enhances serum bactericidal activity on a mannose-rich isolate of Salmonella.
- Binding and release of C3 from Leishmania donovani promastigotes during incubation in normal human serum.
- Purification, toxicity, and antiendotoxin activity of polymyxin B nonapeptide.
- Halogenation and proteolysis of complement component C3 on Salmonella typhimurium during phagocytosis by human neutrophils.
- CR1, the C3b receptor, mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages.
- Complement binding on serum-sensitive and serum-resistant transformants of Neisseria gonorrhoeae: effect of presensitization with a non-bactericidal monoclonal antibody.
- Complement activation and C3 binding by serum-sensitive and serum-resistant strains of Pseudomonas aeruginosa.
- Interaction of Neisseria gonorrhoeae with classical complement components, C1-inhibitor, and a monoclonal antibody directed against the Neisserial H.8 antigen.
- The opsonizing ligand on Salmonella typhimurium influences incorporation of specific, but not azurophil, granule constituents into neutrophil phagosomes.
- Identification of membrane components of Trypanosoma cruzi modulators of complement system.
- C3b generation is affected by the structure of the O-antigen polysaccharide in lipopolysaccharide from salmonellae.
- Lipopolysaccharide size and distribution determine serum resistance in Salmonella montevideo.
- Quantitation of activation of the human terminal complement pathway by ELISA.
- C3 binds preferentially to long-chain lipopolysaccharide during alternative pathway activation by Salmonella montevideo.
- Toxoplasma gondii: fusion competence of parasitophorous vacuoles in Fc receptor-transfected fibroblasts.
- Serum resistance of metacyclic stage Leishmania major promastigotes is due to release of C5b-9.
- Strategies of obligate intracellular parasites for evading host defences.
- Characterization of host cell-derived membrane proteins of the vacuole surrounding different intracellular forms of Trypanosoma cruzi in J774 cells. Evidence for phago...
- Laminin enhances binding of Toxoplasma gondii tachyzoites to J774 murine macrophage cells.
- Desialylation of lysosomal membrane glycoproteins by Trypanosoma cruzi: a role for the surface neuraminidase in facilitating parasite entry into the host cell cytoplasm.
- Laminin on Toxoplasma gondii mediates parasite binding to the beta 1 integrin receptor alpha 6 beta 1 on human foreskin fibroblasts and Chinese hamster ovary cells.
- A sensitive microassay for the murine alternative complement pathway.
- Antimicrobial therapy of digestive diseases.
- Coinfection of fibroblasts with Coxiella burnetti and Toxoplasma gondii: to each their own.
- Toxoplasma gondii: are host cell adenosine nucleotides a direct source for purine salvage?
- Targeting to rhoptry organelles of Toxoplasma gondii involves evolutionarily conserved mechanisms.
- Integrating geriatrics into clinical training, research training, board certification, and continuing education in infectious diseases: meeting review and commentary.
- Toxoplasma gondii exploits host low-density lipoprotein receptor-mediated endocytosis for cholesterol acquisition.
- Toxoplasma gondii: conserved protein machinery in an unusual secretory pathway?
- Differential sorting and post-secretory targeting of proteins in parasitic invasion.
- Targeting and subcellular localization of Toxoplasma gondii catalase. Identification of peroxisomes in an apicomplexan parasite.
- The expression and distribution of dense granule proteins in the enteric (Coccidian) forms of Toxoplasma gondii in the small intestine of the cat.
- Targeted reduction of nucleoside triphosphate hydrolase by antisense RNA inhibits Toxoplasma gondii proliferation.
- Constitutive calcium-independent release of Toxoplasma gondii dense granules occurs through the NSF/SNAP/SNARE/Rab machinery.
- Basis for substrate specificity of the Toxoplasma gondii nucleoside triphosphate hydrolase.
- Upstream elements required for expression of nucleoside triphosphate hydrolase genes of Toxoplasma gondii.
- The protozoan parasite Toxoplasma gondii targets proteins to dense granules and the vacuolar space using both conserved and unusual mechanisms.
Schools
University Of Colorado School Of Medicine
Royal Victoria Hospital McGill
Dartmouth Medical School
McGill University
Tufts University New England Medical Center
Doctors Specialties
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
Awards
- Elected Member
- Fellow, Elected
Education
-
Yale University -
Tufts Medical Center -
Dartmouth-Hitchcock Medical Center -
University of Colorado Denver School of Medicine
Helpful Reviews
Similar Doctors
|
|
Dr. Richard J. Feldman, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Richard M. Mandel, MD |
|
|
Dr. Scott A. Hamstra, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Neil M. Ampel, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Robert N. Hyland, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Andrea M. Giblin, DO
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Marcelo E. Nasif, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Linda M. Gorgos, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Elizabeth E. Wack, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Lawrence J. Lincoln, MD
This Doctor is OpenDoctor Recommended.
|