Physician
Emergency Medicine
Dr. K L. Yielding, MD
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Yielding practices Emergency Medicine. He researched medicine at University of Alabama Medical Center. University of Alabama Medical Center is ranked 37/17 in Research/PrimaryCare. Doctor K L. Yielding, MD is a published MD. He has 101 publications published. The most current publication "Synthesis, separation and characterization of the mono- and diazide analogs of ethidium bromide." Doctor K L. Yielding, MD accepts Medicare payments and is listed with Medicare.gov.
Publications
- A chlorodiazirine analog of pentamidine with anti-trypanosomal activity.
- Anticonvulsant activity of 4-urea-5,7-dichlorokynurenic acid derivatives that are antagonists at the NMDA-associated glycine binding site.
- Kinetoplasts play an important role in the drug responses of Trypanosoma brucei.
- Anticonvulsant activity of antagonists for the NMDA-associated glycine binding site.
- Use of drug-specific antibodies to identify ethidium adducts produced in Trypanosoma brucei by photoaffinity labeling.
- Primary and secondary risk factors for birth defects.
- An axenic propagation of animal infective morphologically normal and dyskinetoplastic forms of Trypanosoma brucei at room temperature.
- Effect of verapamil on antitrypanosomal activity of drugs in mice.
- Production by lithocholic acid of DNA strand breaks in L1210 cells.
- Antitrypanosomal action enhanced by photoaffinity labeling with ethidium analogs.
- DNA excision repair in lymphocytes following photoaffinity labeling with ethidium monoazide.
- Focal cerebellar dystrophy caused by transplacental administration of methylnitrosourea.
- Requirements for induction of DNA strand breaks by lithocholic acid.
- Comparison of petite induction in yeast by acridines, ethidium and their photoaffinity probes.
- Induction of petite "mutants" in an ethidium-resistant strain of Saccharomyces cerevisiae by photoaffinity labeling. Distinction between early and late steps.
- Petite induction in Saccharomyces cerevisiae by ethidium analogs: distinction between resting and growing cells.
- Photoaffinity labeling of DNA.
- Co-mutagenic effects of propidium on petite induction by ethidium in Saccharomyces cerevisiae.
- Demonstration of specific high affinity binding sites in plasmid DNA by photoaffinity labeling with an ethidium analog.
- Observations on epidermal exsorption in mice following injections of procion dyes and ethidium bromide and topically applied dimethyl sulfoxide.
- Involvement of deoxyribonuclease activity in the differential sedimentation rates of nucleoids from non-transformed and transformed mouse embryo fibroblasts.
- Subcellular localization of photoreactive ethidium analogs in Trypanosoma brucei by fluorescence microscopy.
- Ultrastructural studies of barrier restoration in epidermis of hairless mice following dimethyl sulfoxide application.
- Petite induction in Saccharomyces cerevisiae by ethidium analogs. Action on mitochondrial genome.
- Petite and sectored induction in Saccharomyces cerevisiae by propidium iodide: synergistic effect of sodium dodecyl sulfate.
- Induction of cytoplasmically inherited respiration-deficient (''petite'') mutants by photodynamic action of acridine compounds.
- Ethidium binding to deoxyribonucleic acid: spectrophotometric analysis of analogs with amino, azido, and hydrogen substituents.
- Binding of ethidium monoazide to the chromatin in human lymphocytes.
- DNA damage and repair in mouse embryos following treatment transplacentally with methylnitrosourea and methylmethanesulfonate.
- Ethidium binding sites on plasmid DNA determined by photoaffinity labeling.
- Investigations of the possible relation of ferrihemic acid to drug resistance in Plasmodium berghei.
- The dependence of the substrate specificity on the conformation of crystalline glutamate dehydrogenase.
- Response of a "resistant" plasmacytoma to alkylating agents and x-ray in combination with the "excision" repair inhibitors caffeine and chloroquine.
- Nuclear magnetic resonance studies of the interaction of chloroquine diphosphate with adenosine 5''-phosphate and other nucleotides.
- Comparison of chloroquine binding to DNA, and polyadenylic and polyguanylic acids.
- 8-Anilino naphthalene sulfonate binding as a probe for conformational changes induced in glutamate dehydrogenase by regulatory reagents.
- The effect of DNA repair inhibitors on e response of tumors treated with x-ray and alkylating agents.
- Alterations in catalytic and regulatory properties of glutamate dehydrogenase resulting from reaction with one molecule of 14C-labeled methylmercuric iodide.
- Modification by sucrose of the catalytic activity and physical properties of glutamic dehydrogenase.
- Inhibition of DNA and RNA polymerase reactions by chloroquine.
- DNA repair inhibition: a possible mechanism of action of co-carcinogens.
- Chemical modification of the catalytic, regulatory, and physical properties of glutamate dehydrogenase by trinitrobenzene sulfonate.
- The modification by acridine analogs of the survival of ultraviolet irradiated Escherichia coli B.
- Inhibition by chloroquine of UV repair in E. coli B.
- A model for antibody diversity based on non-conservative DNA synthesis errors.
- DNA repair inhibition: a new mechanism of action of steroids with possible implications for tumor therapy.
- A model for aging based on differential repair of somatic mutational damage.
- Editorial: The biological consequences of DNA damage and repair.
- Nucleic acid structural requirement for binding of chloroquine.
- The effect of temperature on the second ionization constant for chloroquine.
- Modification of the catalytic and regulatory properties of glutamate dehydrogenase by N-bromosuccinimide.
- Effect of chemical modification of cysteinyl, lysyl and tyrosyl residues singly and in combination on the catalytic, and regulatory properties of glutamate dehydrogenase.
- Labeling of the active site of glutamate dehydrogenase with a photogenerated species.
- Inhibition of DNA repair by cocarcinogens.
- Inhibition of DNA repair replication by DNA binding drugs which sensitize cells to alkylating agents and X-rays.
- The use of formamide gradients to distinguish between alkali labile regions and single strand breaks in DNA.
- Catalytic properties of glutamate dehydrogenase modified alternatively with methyl- and ethylmercurials, and comparison with modification by silver ion and N-bromosucc...
- Intermediates in the reaction catalyzed by glutamate dehydrogenase.
- Spectral evidence for an intermediate in the glutamate dehydrogenase catalyzed reduction of NAD+ by glutamate.
- Protection of lactate dehydrogenase isozymes from heat inactivation and enzymatic degradation.
- Persistance of the effects of regulatory reagents on conformation of catalytically inactive glutamate dehydrogenase.
- Effects of pH, ionic strength, and metabolic intermediates on the rates of heat inactivation of lactate dehydrogenase isozymes.
- Binding by glutamate dehydrogenase of reduced diphosphopyridine nucleotide. Effects of regulatory ("allosteric") reagents and ionic strength.
- DNA damage and repair in epithelial (mucous) cells and crypt cells from isolated colon.
- Retinal degeneration in the mouse. A model induced transplacentally by methylnitrosourea.
- Application of the fiber-optic perfusion fluorometer to absorption and exsorption studies in hairless mouse skin.
- Petite induction in yeast, Saccharomyces cerevisiae, by phenanthridinium compounds: promotive effects of propidium iodide on mutagenesis by ethidium bromide or 8-deami...
- Retinal degeneration in the mouse induced transplacentally by N-methyl-N-nitrosourea: effects of constant illumination or total darkness.
- Alkali lability and rapid initiation of excision repair following photoaffinity damage by ethidium azide.
- Effects of the antioxidant butylated hydroxytoluene (BHT) on retinal degeneration induced transplacentally by a single low dosage of N-methyl-N-nitrosourea (MNU).
- Late-onset cerebellar degeneration in mice induced transplacentally by methylnitrosourea.
- Who owns research data?
- Use of animals.
- The antioxidant butylated hydroxytoluene can retard cerebellar degeneration induced transplacentally by a single low dosage of N-methyl-N-nitrosourea.
- Preliminary study of caffeine and chloroquine enhancement of x-ray induced birth defects.
- Ga+3 inhibition of glutamate dehydrogenase.
- Evidence for the dark repair of ultraviolet damage in Saccharomyces cerevisiae mitochondrial DNA.
- Enhancement by nalidixic acid of the thermal susceptibility of the Ts-7 mutant of Escherichia coli TAU-bar.
- Bypass by photoaffinity labeling of blocked metabolic activation of ethidium: confirmation of the role for covalent ethidium attachment in mitochondrial mutagenesis.
- A synergistic effect of ultraviolet light and ethidium bromide on petite induction in yeast.
- Selective covalent binding of an ethidium analog to mitochondrial DNA with production of petite mutants in yeast by photoaffinity labelling.
- Immunologic suppression of DNA synthesis in MOPC 104E plasmacytoma cells.
- Synthesis, separation and characterization of the mono- and diazide analogs of ethidium bromide.
- Photoaffinity labels for nucleic acids.
- Repair synthesis in human lymphocytes provoked by photolysis of ethidium azide.
- "Unscheduled" DNA synthesis in lens epithelium following ultraviolet irradiation.
- Production of frameshift mutations in Salmonella by a light sensitive azide analog of ethidium.
- Inhibition by nalidixic acid of post-uv survival of Escherichia coli.
- A protective effect of caffeine on the ethidium induced petite mutation in yeast.
- Inhibition of UV-induced DNA repair at different steps by quinacrine and anthralin.
- Photosensitive cataractogens, chlorpromazine and methoxypsoralen, cause DNA repair synthesis in lens epithelial cells.
- Inhibition by butylated hydroxytoluene of excision repair synthesis and semiconservative DNA synthesis.
- Efficiency of photolytic binding of ethidium monoazide to nucleic acids and synthetic polynucleotides.
- Direct in vitro photoaffinity labeling of DNA with daunorubicin, adriamycin, and rubidazone.
- Covalent binding of ethidium azide analogs to Salmonella DNA in vivo: competition by ethidium bromide.
- Unscheduled DNA synthesis in rat lens epithelial cells induced by alkylating agents.
- Deletion of mitochondrial genetic markers in yeast by ethidium and the photoaffinity probe, ethidium azide.
- Ethidium bromide enhancement of frameshift mutagenesis caused by photoactivatable ethidium analogs.
- Fate during cell growth of yeast mitochondrial and nuclear DNA after photolytic attachment of the monoazide analog of ethidium.
- Antagonism by propidium of petite induction by ethidium and ethidium azide in Saccharomyces cerevisiae.
Schools
University Of Alabama School Of Medicine
Doctors Specialties
- Emergency Medicine
Accepted Insurances
Education
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University of Alabama Medical Center -
University of Alabama School of Medicine
Drug Facts
| NPI NUMBER | 1730147422 | |
| NPPES Provider LastName | YIELDING | |
| NPPES Provider FirstName | K | |
| NPPES Provider ZIPCode | 356531975 | |
| NPPES Provider State | AL | |
| Specialty Description | Emergency Medicine | |
| Total Claim Count | 122.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 19.0 | |
| Percent Opioid Claims | 15.57 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1730147422 |
| Last Name Of The Provider | YIELDING |
| First Name Of The Provider | K |
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