Renal Division Director, Professor of Medicine and Arthur V. Williams Chair, Medical University of South Carolina

Nephrology

Joshua Lipschutz works in the field of Nephrology. He studied medicine at Indiana University School of Medicine. Indiana University School of Medicine is ranked 45 in research and 47 in primary care medicine He has 20 awards "College Alumni Society Undergraduate Research Award", "NIH KO8 Mentored Scientist Career Development Award (to Dr. Ben Fogelgren in the Lipschutz Lab)", "Army commendation medal", "NIH KO1 Mentored Scientist Career Development Award (to Dr. Ben Fogelgren in the Lipschutz Lab)", "Austrian Award for excellence in Bench Research", "Afghanistan Campaign Medal", "NATO Service Meda", "Holmes Award in Bench Research to Nathan Hellman", "Operation Iraqi Freedom Medal", "National Defense Service Medal", "Global War on Terrorism Medal", "Armed Forces Reserve Medal", "Clinical Scientist Career Development Award", "Fellowship Award", "Golden Key National Honor Society", "Phi Beta Kappa", "Alpha Chi Sigma Chemistry Honorary", "Indiana Hoosier Academic Scholarship", "Phi Eta Sigma Freshman Honorary, Officer" and "National Merit Semi-finalist". Joshua H. Lipschutz is a published doctor. He published 51 publications, including: 'Hepatocyte growth factor and the kidney: it is not just for the liver.'

Publications

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• Dynamin Binding Protein (Tuba) deficiency inhibits ciliogenesis and nephrogenesis in vitro and in vivo.
• Arl13b and the exocyst interact synergistically in ciliogenesis.
• Wnt5a Is Necessary for Normal Kidney Development in Zebrafish and Mice.
• Exocyst Sec10 Protects Renal Tubule Cells from Injury by EGFR/MAPK Activation and Effects on Endocytosis.
• Cilia and polycystic Kidney disease, kith and kin.
• Novel MAPK-dependent and independent tubulogenes identified via microarray analysis of 3D-cultured Madin-Darby canine Kidney cells.
• Expression of Drosophila forkhead transcription factors during Kidney development.
• The small GTPase Cdc42 is necessary for primary ciliogenesis in renal tubular epithelial cells.
• The Exocyst Protein Sec10 Interacts with Polycystin-2 and Knockdown Causes PKD-Phenotypes.
• Exocyst Sec10 protects epithelial barrier integrity and enhances recovery following oxidative stress, by activation of the MAPK pathway.
• The exocyst protein Sec10 is necessary for primary ciliogenesis and cystogenesis in vitro.
• Tubule and cyst formation: lightning strikes twice.
• Matrix metalloproteinase 13 (MMP13) and tissue inhibitor of matrix metalloproteinase 1 (TIMP1), regulated by the MAPK pathway, are both necessary for Madin-Darby canin...
• Branching out.
• Practical advance in obtaining an emergency airway via cricothyroidotomy.
• Intracellular signaling via ERK/MAPK completes the pathway for tubulogenic fibronectin in MDCK cells.
• Activated extracellular signal-regulated kinases are necessary and sufficient to initiate tubulogenesis in renal tubular MDCK strain I cell cysts.
• Extracellular signal-regulated kinases 1/2 control claudin-2 expression in Madin-Darby canine Kidney strain I and II cells.
• Religiosity in a hemodialysis population and its relationship to satisfaction with medical care, satisfaction with life, and adherence.
• Asaia bogorensis peritonitis identified by 16S ribosomal RNA sequence analysis in a patient receiving peritoneal dialysis.
• ERK and MMPs sequentially regulate distinct stages of epithelial tubule development.
• The exocyst localizes to the primary cilium in MDCK cells.
• Gene expression alterations during HGF-induced dedifferentiation of a renal tubular epithelial cell line (MDCK) using a novel canine DNA microarray.
• The exocyst affects protein synthesis by acting on the translocation machinery of the endoplasmic reticulum.
• The Rho family of small GTPases is involved in epithelial cystogenesis and tubulogenesis.
• Recent advances in the cell biology of polycystic Kidney disease.
• High rate of fistula placement in a cohort of dialysis patients in a single payer system.
• Electronic health records in hospitals.
• Analysis of membrane traffic in polarized epithelial cells.
• The bioethics and utility of selling Kidneys for renal transplantation.
• Simvastatin protection against acute immune-mediated glomerulonephritis in mice.
• Laparoscopic cholecystectomy and ERCP with sphincterotomy in an elderly patient with situs inversus.
• Bilateral anterior cerebral artery infarction resulting from explosion-type injury to the head and neck.
• Unreliability of the abdominal fat pad biopsy in the evaluation of nephrosis: report of 3 consecutive cases.
• Reset osmostat in a healthy patient.
• Phenylacetate is an inhibitor of prostatic growth and development in organ culture.
• Urothelial transformation into functional glandular tissue in situ by instructive mesenchymal induction.
• Keratinocyte growth factor (KGF) can replace testosterone in the ductal branching morphogenesis of the rat ventral prostate.
• Differentiation of rat neonatal ventral prostates grown in a serum-free organ culture system.
• Molecular development of the Kidney: a review of the results of gene disruption studies.
• Expression of beta-catenin and gamma-catenin in epithelial tumor cell lines and characterization of a unique cell line.
• Hepatocyte growth factor and the Kidney: it is not just for the liver.
• To clone or not to clone--a Jewish perspective.
• Clonality of urogenital organs as determined by analysis of chimeric mice.
• Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins.
• Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line.
• Cdc42 interacts with the exocyst and regulates polarized secretion.
• Exocytosis: the many masters of the exocyst.
• The effect of testosterone on androgen receptors and human penile growth.
• A Possible Zebrafish Model of Polycystic Kidney Disease: Knockdown of wnt5a Causes Cysts in Zebrafish Kidneys.

Schools

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• Indiana University School Of Medicine

• Clarian Indiana University Hospital

Conditions Treated

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• Hypertensive Heart and Chronic Kidney Disease

Doctors Specialties

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• Nephrology

Accepted Insurances

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Awards

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• College Alumni Society Undergraduate Research Award
• NIH KO8 Mentored Scientist Career Development Award (to Dr. Ben Fogelgren in the Lipschutz Lab)
• Army commendation medal
• NIH KO1 Mentored Scientist Career Development Award (to Dr. Ben Fogelgren in the Lipschutz Lab)
• Austrian Award for excellence in Bench Research
• Afghanistan Campaign Medal
• NATO Service Meda
• Holmes Award in Bench Research to Nathan Hellman
• Operation Iraqi Freedom Medal
• National Defense Service Medal
• Global War on Terrorism Medal
• Armed Forces Reserve Medal
• Clinical Scientist Career Development Award
• Fellowship Award
• Golden Key National Honor Society
• Phi Beta Kappa
• Alpha Chi Sigma Chemistry Honorary
• Indiana Hoosier Academic Scholarship
• Phi Eta Sigma Freshman Honorary, Officer
• National Merit Semi-finalist

Education

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• Indiana University School of Medicine
• Indiana University

Hospital

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• Philadelphia Veterans Affairs Medical Center
• Hospital of the University of Pennsylvania

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