Bernardo Hirschman MD, Jose A. Apud MD, PhD, PA

Psychiatry

Jose A. Apud, MD is an expert in the field of Psychiatry. He received 6 awards: "Overseas Fellow", "The NIH Directors Award", "Burroughs Wellcome Fellow", "NIMH/Upjohn Most Outstanding Resident Award", "CEDIQUIFA Award in Pharmacology" and "Super Doctor". Doctor Jose A. Apud, MD is a published physician. He has 32 papers published. The most current publication "Treatment of tardive dyskinesia."

Publications

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• Identification of Candidate Single-nucleotide Polymorphisms in NRXN1 Related to Antipsychotic Treatment Response in Patients with Schizophrenia.
• Perceptual Category Judgment Deficits are Related to Prefrontal Decision Making Abnormalities in Schizophrenia.
• Dopaminergic therapy removal differentially effects learning in schizophrenia and Parkinson's disease.
• Effect of tolcapone on brain activity during a variable attentional control task: a double-blind, placebo-controlled, counter-balanced trial in healthy volunteers.
• Hippocampal dysfunction in schizophrenia: association with brain-derived neurotrophic factor genotype.
• Brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia.
• Epistatic interactions of AKT1 on human medial temporal lobe biology and pharmacogenetic implications.
• Genetic variation in KCNH2 associated with expression in the brain of a unique hERG isoform modulates treatment response in patients with schizophrenia.
• The extraction, isolation and purification of an endogenous regulator for the 5-HT(2) receptor.
• Modulatory effects of modafinil on neural circuits regulating emotion and cognition.
• Relative risk of probabilistic category learning deficits in patients with schizophrenia and their siblings.
• Cognitive fitness of cost-efficient brain functional networks.
• Neural correlates of probabilistic category learning in patients with schizophrenia.
• Tolcapone improves cognition and cortical information processing in normal human subjects.
• Pharmacogenetic tools for the development of target-oriented cognitive-enhancing drugs.
• Catechol-O-methyltransferase val108/158met genotype predicts working memory response to antipsychotic medications.
• Graph theoretical analysis of resting magnetoencephalographic functional connectivity networks.
• Functional Brain Network Characterization and Adaptivity during Task Practice in Healthy Volunteers and People with Schizophrenia.
• Magnetoencephalographic gamma power reduction in patients with schizophrenia during resting condition.
• Dopamine effect on the mitochondria potential in B lymphocytes of schizophrenic patients and normal controls.
• Neuroleptic withdrawal in treatment-resistant patients with schizophrenia: tardive dyskinesia is not associated with supersensitive psychosis.
• Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain.
• Context binding in schizophrenia: effects of clinical symptomatology and item content.
• Effects of smoking during antipsychotic withdrawal in patients with chronic schizophrenia.
• Treatment of tardive dyskinesia.
• New directions in the prevention and treatment of schizophrenia: a biological perspective.
• The 5-HT2 receptor in brain: recent biochemical and molecular biological developments and new perspectives in its regulation.
• The 5-HT3 receptor in mammalian brain: a new target for the development of psychotropic drugs?
• Semi-preparative purification of an endogenous ligand for brain serotonin-2 receptors by coil planet centrifuge counter-current chromatography.
• Pharmacological characterization of regulation of phosphoinositide metabolism by recombinant 5-HT2 receptors of the rat.
• Dopamine reuptake inhibitors and dopamine releasers: differential effect on plasma prolactin in the rat.

Schools

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• Universidad Nacional De Tucuman Facultad De Medicina

• National Institutes Of Health Clinical Center

• St Elizabeth39s Hospital

• French Hospital

• National Atomic Energy Commission

• University Of Milan

Procedures Preformed

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• Psychiatric Evaluation
• Psychotherapy and Psychophysiological Therapy (incl. Biofeedback)

Conditions Treated

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• Anxiety
• Bipolar Disorder

Doctors Specialties

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• Psychiatry

Accepted Insurances

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Awards

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• Overseas Fellow
• The NIH Director’s Award
• Burroughs Wellcome Fellow
• NIMH/Upjohn Most Outstanding Resident Award
• CEDIQUIFA Award in Pharmacology
• Super Doctor

Education

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• National Institutes of Health Clinical Center
• Georgetown University Hospital
• National University of Tucuman Faculty of Medicine

Hospital

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• Inova Fairfax Hospital

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