Associate Professor of Pediatrics, Boston Children's Hospital
Pediatrics
Dr. Jordan A. Kreidberg, MD
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Jordan Kreidberg is an expert in the field of Pediatrics. He went to medical school at Johns Hopkins University School of Medicine. Johns Hopkins University School of Medicine is a top medical college. Johns Hopkins University School of Medicine has a rank of 3 in research and a 29 in primary care Jordan A. Kreidberg, MD is a published doctor. He published 80 publications, including: 'Neuronal receptors mediating responses to antibodyactivated laminin-1.'
Publications
- WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals.
- Genome-Wide Analysis of Wilms' Tumor 1-Controlled Gene Expression in Podocytes Reveals Key Regulatory Mechanisms.
- Identification of Novel Glycans with Disialylated Structures in α3 Integrin from Mouse Kidney Cells with the Phenotype of Polycystic Kidney Disease.
- Introduction to the 12th international workshop on developmental nephrology.
- Dicer function is required in the metanephric mesenchyme for early kidney development.
- α6β1 and α7β1 Integrins Are Required in Schwann Cells to Sort Axons.
- MicroRNAs in renal development.
- c-Met and NF-κB-Dependent Overexpression of Wnt7a and -7b and Pax2 Promotes Cystogenesis in Polycystic Kidney Disease.
- WT1-Dependent Sulfatase Expression Maintains the Normal Glomerular Filtration Barrier.
- The Pro-Apoptotic Protein Bim Is a MicroRNA Target in Kidney Progenitors.
- Systems biology approach to identify transcriptome reprogramming and microRNA targets during the progression of Polycystic Kidney Disease.
- Dystroglycan does not contribute significantly to kidney development or function, in health or after injury.
- Failure to ubiquitinate c-Met leads to hyperactivation of mTOR signaling in a mouse model of autosomal dominant polycystic kidney disease.
- Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF.
- siRNA therapy for glomerulonephritis.
- WT1 and kidney progenitor cells.
- G alpha 12 inhibits alpha2 beta1 integrin-mediated Madin-Darby canine kidney cell attachment and migration on collagen-I and blocks tubulogenesis.
- Netrin-1-alpha3beta1 integrin interactions regulate the migration of interneurons through the cortical marginal zone.
- Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis.
- Diverse roles of E-cadherin in the morphogenesis of the submandibular gland: insights into the formation of acinar and ductal structures.
- Podocyte-derived BMP7 is critical for nephron development.
- Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury.
- Wilms' tumor-1: a riddle wrapped in a mystery, inside a kidney.
- Integrins and matrix in the glomerulus: old mysteries and new insights.
- Reelin, integrin and DAB1 interactions during embryonic cerebral cortical development.
- Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin.
- Induction of B7-1 in podocytes is associated with nephrotic syndrome.
- Wt1 functions in the development of germ cells in addition to somatic cell lineages of the testis.
- alpha3beta1 integrin-CD151, a component of the cadherin-catenin complex, regulates PTPmu expression and cell-cell adhesion.
- Distinct ligand binding sites in integrin alpha3beta1 regulate matrix adhesion and cell-cell contact.
- Role of the WT1 tumor suppressor in murine hematopoiesis.
- Podocyte differentiation and glomerulogenesis.
- None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusion.
- A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development.
- Regulation of cadherin junctions during mouse submandibular gland development.
- A mammal-specific exon of WT1 is not required for development or fertility.
- Palmitoylation of tetraspanin proteins: modulation of CD151 lateral interactions, subcellular distribution, and integrin-dependent cell morphology.
- Applications of adhesion molecule gene knockout cell lines.
- GPR56 Functions Together with α3β1 Integrin in Regulating Cerebral Cortical Development.
- Genetic analysis of the human thymidine kinase gene promoter.
- WT-1 is required for early kidney development.
- Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion.
- Gene targeting in kidney development.
- Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis.
- Induction of p21 by the Wilms' tumor suppressor gene WT1.
- Differential regulation of two sets of mesonephric tubules by WT-1.
- alpha3beta1 Integrin is required for normal development of the epidermal basement membrane.
- Novel roles for alpha3beta1 integrin as a regulator of cytoskeletal assembly and as a trans-dominant inhibitor of integrin receptor function in mouse keratinocytes.
- Neuronal receptors mediating responses to antibodyactivated laminin-1.
- Distinct functions of alpha3 and alpha(v) integrin receptors in neuronal migration and laminar organization of the cerebral cortex.
- Mouse primordial germ cells lacking beta1 integrins enter the germline but fail to migrate normally to the gonads.
- Coordinate action of Wt1 and a modifier gene supports embryonic survival in the oviduct.
- YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis.
- Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud.
- Synergistic activities of alpha3 and alpha6 integrins are required during apical ectodermal ridge formation and organogenesis in the mouse.
- (Alpha)3(beta)1 integrin regulates epithelial cytoskeletal organization.
- Overlapping and independent functions of fibronectin receptor integrins in early mesodermal development.
- The LIM homeobox gene Lhx9 is essential for mouse gonad formation.
- Mouse keratinocytes immortalized with large T antigen acquire alpha3beta1 integrin-dependent secretion of MMP-9/gelatinase B.
- Integrins in kidney development, function, and disease.
- alpha3beta1 and alpha6beta4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development.
- Reelin binds alpha3beta1 integrin and inhibits neuronal migration.
- Functions of alpha3beta1 integrin.
- Loss of alpha3beta1 integrin function results in an altered differentiation program in the mouse submandibular gland.
- Epithelial development and differentiation in the mammary gland is not dependent on alpha 3 or alpha 6 integrin subunits.
- Induction of ureter branching as a response to Wnt-2b signaling during early kidney organogenesis.
- Urokinase receptors promote beta1 integrin function through interactions with integrin alpha3beta1.
- Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development.
- Kidneys and sex, the Wilms' tumor connection.
- Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa.
- Analysis of Netrin 1 receptors during inner ear development.
- Development of the renal glomerulus: good neighbors and good fences.
- Differential expression of collagen- and laminin-binding integrins mediates ureteric bud and inner medullary collecting duct cell tubulogenesis.
- Transcriptional activation of placental growth factor by the forkhead/winged helix transcription factor FoxD1.
- Genomic characterization of Wilms'' tumor suppressor 1 targets in nephron progenitor cells during kidney development.
- Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche.
- Alpha3beta1 integrin in epidermis promotes wound angiogenesis and keratinocyte-to-endothelial-cell crosstalk through the induction of MRP3.
- alpha3beta1 integrin modulates neuronal migration and placement during early stages of cerebral cortical development.
- Coordinate integrin and c-Met signaling regulate Wnt gene expression during epithelial morphogenesis.
Schools
Johns Hopkins University School of Medicine
Children39s Hospital Boston
Doctors Specialties
- Pediatrics
Accepted Insurances
Education
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Boston Children's Hospital -
Johns Hopkins University School of Medicine
Hospital
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Boston Children's Hospital
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