Physician
Anesthesiology
Dr. Jonathan D. Bloom, MD
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Jonathan Bloom works in the field of Anesthesiology. He went to University of Pittsburgh School of Medicine. Jonathan Bloom is a published physician as well. He has 16 publications published. The latest was: New insights into the effect of rapid transfusion of fresh frozen plasma on ionized calcium.
Publications
- New insights into the effect of rapid transfusion of fresh frozen plasma on ionized calcium.
- Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor which significantly decreases tumor volume in a mouse xenograft model.
- Macrocyclic lactams as potent Hsp90 inhibitors with excellent tumor exposure and extended biomarker activity.
- Restructuring within an academic health center to support quality and safety: the development of the Center for Quality and Safety at the Massachusetts General Hospital.
- Specific inhibition of human cytomegalovirus glycoprotein B-mediated fusion by a novel thiourea small molecule.
- Identification of small molecule compounds that selectively inhibit varicella-zoster virus replication.
- Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase.
- Discovery of pyrano[3,4-b]indoles as potent and selective HCV NS5B polymerase inhibitors.
- Thiourea inhibitors of herpes viruses. Part 1: bis-(aryl)thiourea inhibitors of CMV.
- Pyrimido[1,2-b]-1,2,4,5-tetrazin-6-ones as HCMV protease inhibitors: a new class of heterocycles with flavin-like redox properties.
- Thiourea inhibitors of herpesviruses. Part 3: Inhibitors of varicella zoster virus.
- Thiourea inhibitors of herpes viruses. Part 2: N-Benzyl-N''-arylthiourea inhibitors of CMV.
- Novel pyrazolopyrimidines as highly potent B-Raf inhibitors.
- Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity.
- Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft m...
Schools
University of Pittsburgh School of Medicine
Upmc Mercy
Massachusetts General Hospital
Doctors Specialties
- Anesthesiology
- Neurosurgery
Accepted Insurances
Education
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Massachusetts General Hospital -
University of Pittsburgh Medical Center-Mercy Hospital -
University of Pittsburgh School of Medicine
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