Physician

General Surgery

Dr. John R. Klune, MD

Doctor John R. Klune, MD practices General Surgery. He went to medical school at University of Pittsburgh School of Medicine. He received 1 awards: "Fellow (FACS)". John Klune is also published. He has 16 publications published. The lastest publication: "Cellular specific role of toll-like receptor 4 in hepatic ischemia-reperfusion injury.'

Publications

Cellular specific role of toll-like receptor 4 in hepatic ischemia-reperfusion injury.
Identifying occult arterial bleeding by a relaxing (loosening) pelvic stabilization device in severe pelvic fracture.
Delayed operating room availability significantly impacts the total hospital costs of an urgent surgical procedure.
Interferon regulatory factor 1 mediates acetylation and release of high mobility group box 1 from hepatocytes during murine liver ischemia-reperfusion injury.
High mobility group box 1 release from hepatocytes during ischemia and reperfusion injury is mediated by decreased histone deacetylase activity.
Molecular biology of liver ischemia/reperfusion injury: established mechanisms and recent advancements.
Critical role of interferon regulatory factor-1 in murine liver transplant ischemia reperfusion injury.
Arginase blockade protects against hepatic damage in warm ischemia-reperfusion.
Noninvasive radiofrequency ablation of cancer targeted by gold nanoparticles.
HMGB1: endogenous danger signaling.
HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signaling.
A novel inhibitory peptide of Toll-like receptor signaling limits lipopolysaccharide-induced production of inflammatory mediators and enhances survival in mice.
Increasing numbers of hepatic dendritic cells promote HMGB1-mediated ischemia-reperfusion injury.
HMGB1 preconditioning: therapeutic application for a danger signal?
Isolated skeletal muscle metastasis following successful treatment of laryngeal cancer: case report.

Schools

Univ Of Pittsburgh Sch Of Med

Doctors Specialties

General Surgery

Accepted Insurances

Awards

Fellow (FACS)

Education

University of Pittsburgh Medical Center
University of Pittsburgh School of Medicine

Helpful Reviews

Give Anonymous Review

Similar Doctors

	Dr. Harry K. Williams Jr., MD This Doctor is OpenDoctor Recommended.
	Dr. Elan Jeremitsky, MD This Doctor is OpenDoctor Recommended.
	Dr. Alain Corcos, MD This Doctor is OpenDoctor Recommended.
	Dr. Stuart H. Chetlin, MD This Doctor is OpenDoctor Recommended.
	Dr. Hiroshi Sogawa, MD This Doctor is OpenDoctor Recommended.
	Dr. Joshua B. Brown, MD
	Dr. Tara L. Grahovac, MD This Doctor is OpenDoctor Recommended.
	Dr. Anthony B. Longhini, MD
	Dr. Mashaal Dhir, MD This Doctor is OpenDoctor Recommended.