Physician
Pathology
Dr. John L. Portis, MD
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John Portis practices Pathology. John L. Portis, MD is a published MD. He published 74 publications, including: 'Mapping of a neurovirulence determinant within the envelope protein of a polytropic murine retrovirus: induction of central nervous system disease by low levels of virus.'
Publications
- The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3.
- Disease-associated prion protein oligomers inhibit the 26S proteasome.
- Oligodendrocytes are a major target of the toxicity of spongiogenic murine retroviruses.
- Prion-induced amyloid heart disease with high blood infectivity in transgenic mice.
- Endoplasmic reticulum (ER) stress induced by a neurovirulent mouse retrovirus is associated with prolonged BiP binding and retention of a viral protein in the ER.
- Endoplasmic reticulum stress is a determinant of retrovirus-induced spongiform neurodegeneration.
- Perspectives on the role of endogenous human retroviruses in autoimmune diseases.
- Increased neurovirulence of polytropic mouse retroviruses delivered by inoculation of brain with infected neural stem cells.
- A neutralizable epitope common to the envelope glycoproteins of ecotropic, polytropic, xenotropic, and amphotropic murine leukemia viruses.
- Characterization of Ia8 antigen, thy-1.2 antigen, complement receptors, and virus production in a group of murine virus-induced leukemia cell lines.
- Lymphoid subpopulation changes in regional lymph nodes in squamous head and neck cancer.
- Failure of human immunodeficiency virus entry and infection in CD4-positive human brain and skin cells.
- Protective efficacy of nonneutralizing monoclonal antibodies in acute infection with murine leukemia virus.
- Characterization of mouse monoclonal antibodies specific for Friend murine leukemia virus-induced erythroleukemia cells: friend-specific and FMR-specific antigens.
- Monoclonal antibodies distinguish phase variants of Coxiella burnetii.
- Effect of murine host genotype on MCF virus expression, latency, and leukemia cell type of leukemias induced by Friend murine leukemia helper virus.
- Monoclonal antibodies to xenotropic and MCF murine leukemia viruses derived during the graft-versus-host reaction.
- Identification of a unique erythroleukemia-associated retroviral gp70 expressed during early stages of normal erythroid differentiation.
- Monoclonal antibodies derived during graft-versus-host reaction. II. Antibodies detect unique determinants common to many MCF viruses.
- Naturally occurring leukemia viruses in H-2 congenic C57BL mice. III. Characterization of C-type viruses isolated from lymphomas induced by milk transmission of B-ecot...
- MCF-specific murine monoclonal antibodies made against AKR-247 MCF virus recognize a unique determinant associated with the gp70-p-15(E) complex.
- Dissociation of H-2 recognition by antibody and cytotoxic T cells of a cloned murine leukemia cell line.
- Infectious entry of murine retroviruses into mouse cells: evidence of a postadsorption step inhibited by acidic pH.
- Monoclonal antibodies specific for wild mouse neurotropic retrovirus: detection of comparable levels of virus replication in mouse strains susceptible and resistant to...
- Horizontal transmission of murine retroviruses.
- Identification of two forms of an endogenous murine retroviral env gene linked to the Rmcf locus.
- A population of murine hematopoietic progenitors expresses an endogenous retroviral gp70 linked to the Rmcf gene and associated with resistance to erythroleukemia.
- The endogenous mink cell focus-forming (MCF) gp70 linked to the Rmcf gene restricts MCF virus replication in vivo and provides partial resistance to erythroleukemia in...
- Neurodegenerative disease induced by the wild mouse ecotropic retrovirus is markedly accelerated by long terminal repeat and gag-pol sequences from nondefective Friend...
- Wild mouse retrovirus: pathogenesis.
- Host genes conferring resistance to a central nervous system disease induced by a polytropic recombinant Friend murine retrovirus.
- The R-U5-5' leader sequence of neurovirulent wild mouse retrovirus contains an element controlling the incubation period of neurodegenerative disease.
- Age-dependent resistance to murine retrovirus-induced spongiform neurodegeneration results from central nervous system-specific restriction of virus replication.
- Complete nucleotide sequence of the neurotropic murine retrovirus CAS-BR-E.
- Changes in the transplantability of a virus-induced murine leukemia tumor.
- Vascular permeability changes in the central nervous system of rats with hyperacute experimental allergic encephalomyelitis induced with the aid of a substance from Bo...
- Deposition of IgA in renal glomeruli of mink affected with Aleutian disease.
- Functional studies of membrane-bound immunoglobulin on hamster macrophages and mast cells.
- Murine retrovirus-induced spongiform encephalopathy: productive infection of microglia and cerebellar neurons in accelerated CNS disease.
- Infectivity of retroviral DNA in vivo.
- Murine retrovirus-induced spongiform encephalomyelopathy: host and viral factors which determine the length of the incubation period.
- The immune response in the hamster. VII. Studies on cytophilic immunoglobulin.
- IgM the secretory immunoglobulin of reptiles and amphibians.
- Immune response in the garter snake (Thamnophis ordinoides).
- Immune response in the hamster. VIII. Ig class differences in susceptibility to tolerance induction.
- A simplified rapid method for purification of glomeruli.
- Mapping of a neurovirulence determinant within the envelope protein of a polytropic murine retrovirus: induction of central nervous system disease by low levels of virus.
- Dissecting the determinants of neuropathogenesis of the murine oncornaviruses.
- The neuroinvasiveness of a murine retrovirus is influenced by a dileucine-containing sequence in the cytoplasmic tail of glycosylated Gag.
- Distinct homing pathways direct T lymphocytes to the genital and intestinal mucosae in Chlamydia-infected mice.
- Characterization of glycosylated Gag expressed by a neurovirulent murine leukemia virus: identification of differences in processing in vitro and in vivo.
- Neurologic disease induced by polytropic murine retroviruses: neurovirulence determined by efficiency of spread to microglial cells.
- Late virus replication events in microglia are required for neurovirulent retrovirus-induced spongiform neurodegeneration: evidence from neural progenitor-derived chim...
- The glycosylated gag protein of MuLV is a determinant of neuroinvasiveness: analysis of second site revertants of a mutant MuLV lacking expression of this protein.
- Murine retrovirus-induced spongiform encephalopathy: disease expression is dependent on postnatal development of the central nervous system.
- Kinetic analysis of spongiform neurodegenerative disease induced by a highly virulent murine retrovirus.
- Identification of a sequence in the unique 5' open reading frame of the gene encoding glycosylated Gag which influences the incubation period of neurodegenerative dise...
- Microglial infection by a neurovirulent murine retrovirus results in defective processing of envelope protein and intracellular budding of virus particles.
- Induction of focal spongiform neurodegeneration in developmentally resistant mice by implantation of murine retrovirus-infected microglia.
- Prevention of retrovirus-induced neurological disease by infection with a nonneuropathogenic retrovirus.
- Endogenous retroviral envelope antigens recognized by B lymphocytes during graft-versus-host reaction.
- Biological characterization and molecular cloning of murine C-type retroviruses derived from the TSZ complex from mainland China.
- Characterization of a neurologic disease induced by a polytropic murine retrovirus: evidence for differential targeting of ecotropic and polytropic viruses in the brain.
- Inhibition of murine retrovirus-induced neurodegeneration in the spinal cord by explant culture.
- N-terminal cleavage fragment of glycosylated Gag is incorporated into murine oncornavirus particles.
- Genetic determinants of neurovirulence of murine oncornaviruses.
- Differences in cytokine and chemokine responses during neurological disease induced by polytropic murine retroviruses Map to separate regions of the viral envelope gene.
- Increased expression of MIP-1 alpha and MIP-1 beta mRNAs in the brain correlates spatially and temporally with the spongiform neurodegeneration induced by a murine onc...
- Inflammation and clearance of Chlamydia trachomatis in enteric and nonenteric mucosae.
- Neural stem cells as tools for understanding retroviral neuropathogenesis.
- Brain infection by neuroinvasive but avirulent murine oncornaviruses.
- The degree of folding instability of the envelope protein of a neurovirulent murine retrovirus correlates with the severity of the neurological disease.
- Prion proteins meet protein quality control.
Schools
University of California At Los Angeles
Doctors Specialties
- Anatomic Pathology
- Pathology
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