Professor and Chief, Division of Allergy, Immunology and Rheumatology Vice Chair, Clinical Enterprise Department of Pediatrics Executive Medical Officer University of Utah Medical Group University of Utah Health Sciences Center
Pediatric Rheumatology
Dr. John F. Bohnsack, MD
|
|
Give Review
John Bohnsack practices Pediatric Rheumatology. He attended University of Virginia School of Medicine. He received 3 awards: "Regional Top Doctor", "Top MD" and "Fellow". John Bohnsack is a published doctor. He has 101 papers published. The most current publication "Identification of a highly encapsulated, genetically related group of invasive type III group B streptococci."
Publications
- Extension Study of Participants from the Trial of Early Aggressive Therapy in Juvenile Idiopathic Arthritis.
- Autoimmunity due to RAG deficiency and estimated Disease incidence in RAG1/2 mutations.
- Germline Mutations in NFKB2 Implicate the Noncanonical NF-κB Pathway in the Pathogenesis of Common Variable Immunodeficiency.
- Susceptibility to childhood-onset rheumatoid Arthritis: investigation of a weighted genetic risk score that integrates cumulative effects of variants at five genetic l...
- Cryopyrin-associated Periodic Syndromes and the Eye.
- Hierarchy of risk of childhood onset rheumatoid Arthritis conferred by HLA-DRB1 alleles encoding the shared epitope.
- Quantification of the familial contribution to juvenile idiopathic Arthritis.
- Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic Arthritis.
- Human Streptococcus agalactiae isolate in Nile tilapia (Oreochromis niloticus).
- Lack of association of functional CTLA4 polymorphisms with juvenile idiopathic Arthritis.
- Population structure of invasive and colonizing strains of Streptococcus agalactiae from neonates of six U.S. Academic Centers from 1995 to 1999.
- L-Ficolin/mannose-binding lectin-associated serine protease complexes bind to group B streptococci primarily through N-acetylneuraminic acid of capsular polysaccharide...
- Phylogenetic lineages of invasive and colonizing strains of serotype III group B Streptococci from neonates: a multicenter prospective study.
- Septic, CD-30 positive febrile ulceronecrotic pityriasis lichenoides et varioliformis acuta.
- Fatal acute fibrinous and organizing pneumonia in a child with Juvenile dermatomyositis.
- Role of L-ficolin/mannose-binding lectin-associated serine protease complexes in the opsonophagocytosis of type III group B streptococci.
- Serotype III Streptococcus agalactiae from bovine milk and human neonatal infections.
- Leukoencephalopathy, arthritis, colitis, and hypogammaglobulinemia (LACH) in two brothers: a novel Syndrome?
- D8/17 and CD19 expression on lymphocytes of patients with acute rheumatic fever and Tourette's disorder.
- Subtractive hybridization identifies a novel predicted protein mediating epithelial cell invasion by virulent serotype III group B Streptococcus agalactiae.
- Beta-hemolysin-independent induction of apoptosis of macrophages infected with serotype III group B streptococcus.
- Lack of association between birth order and juvenile idiopathic Arthritis.
- Multilocus sequence typing system for group B streptococcus.
- A novel streptococcal surface protease promotes virulence, resistance to opsonophagocytosis, and cleavage of human fibrinogen.
- Correlation of phylogenetic lineages of group B Streptococci, identified by analysis of restriction-digestion patterns of genomic DNA, with infB alleles and mobile gen...
- Long-range mapping of the Streptococcus agalactiae phylogenetic lineage restriction digest pattern type III-3 reveals clustering of virulence genes.
- Lack of association between beta 2-adrenergic receptor polymorphisms and juvenile idiopathic Arthritis.
- Cyclosporine A in juvenile idiopathic Arthritis. Results of the PRCSG/PRINTO phase IV post marketing surveillance study.
- Effects of muramyl dipeptide on superoxide anion release and on anti-microbial activity of human macrophages.
- Appearance of antibody-producing cells in the peripheral blood in response to immunization with a specific antigen.
- Painless juvenile rheumatoid Arthritis.
- Antibody to bacteriophage phi X 174 synthesized by cultured human peripheral blood lymphocytes.
- Phylogenetic classification of serotype III group B streptococci on the basis of hylB gene analysis and DNA sequences specific to restriction digest pattern type III-3.
- Evidence for early vessel involvement in the dysfunctional myocardium of Takayasu's arteritis.
- Growth failure, intracranial calcifications, acquired pancytopenia, and unusual humoral immunodeficiency: a genetic Syndrome?
- Bacterial genetics and human immunity to group B streptococci.
- Genetic polymorphisms of group B streptococcus scpB alter functional activity of a cell-associated peptidase that inactivates C5a.
- Induction of cyclooxygenase-2 by human monocytes exposed to group B streptococci.
- Childhood polyarteritis nodosa presenting as a relapsing movement disorder.
- Radiological case of the month. Takayasu arteritis.
- Kawasaki Disease: more patients are being diagnosed who do not meet American Heart Association criteria.
- Capsular sialic acid limits C5a production on type III group B streptococci.
- Chronic lung injury in preterm lambs. Disordered respiratory tract development.
- Identification of a highly encapsulated, genetically related group of invasive type III group B streptococci.
- Intracellular calcium requirements for beta1 integrin activation.
- Clinical analysis of a variant of Freeman-Sheldon Syndrome (DA2B).
- Chronic lung injury in preterm lambs: disordered pulmonary elastin deposition.
- A role for C5 and C5a-ase in the acute neutrophil response to group B streptococcal infections.
- A variant of Freeman-Sheldon Syndrome maps to 11p15.5-pter.
- Distal arthrogryposis type 1: clinical analysis of a large kindred.
- Traumatic myositis ossificans simulating soft tissue infection.
- Effects of cytomegalovirus infection on growth factor production in endothelial cells and fibroblasts.
- Restricted ability of group B streptococcal C5a-ase to inactivate C5a prepared from different animal species.
- Fibronectin in host defense: implications in the diagnosis, prophylaxis and therapy of infectious Diseases.
- Mechanism of fibronectin enhancement of group B streptococcal phagocytosis by human neutrophils and culture-derived macrophages.
- Production of tumor necrosis factor by human cells in vitro and in vivo, induced by group B streptococci.
- Effects of fibronectin on actin organization and respiratory burst activity in neutrophils, monocytes, and macrophages.
- A gene for distal arthrogryposis type I maps to the pericentromeric region of chromosome 9.
- Effects of fibronectin and group B streptococci on tumour necrosis factor-alpha production by human culture-derived macrophages.
- Aberrant glycosylation of L-selectin on the lymphocytes of Chronic lymphocytic leukemia.
- Mechanisms of beta 1 integrin-dependent adherence of granulocytic HL60 to fibronectin.
- Activation of beta 1 integrin fibronectin receptors on HL60 cells after granulocytic differentiation.
- Group B streptococci inhibit the chemotactic activity of the fifth component of complement.
- The C1q subunit of the first component of complement binds to laminin: a mechanism for the deposition and retention of immune complexes in basement membrane.
- Mechanism of inhibition of immunoglobulin G-mediated phagocytosis by monoclonal antibodies that recognize the Mac-1 antigen.
- Interaction of culture-derived macrophages with the fibroblast-binding domain of fibronectin is a necessary but inefficient signal for fibronectin enhancement of CR1-m...
- Effects of fibronectin on the interaction of polymorphonuclear leukocytes with unopsonized and antibody-opsonized bacteria.
- An IgA monoclonal antibody directed against type III antigen on group B streptococci acts as an opsonin.
- Neutrophil activating factor (NAF) induces polymorphonuclear leukocyte adherence to endothelial cells and to subendothelial matrix proteins.
- Effect of immune globulin intravenous on opsonization of bacteria by classic and alternative complement pathways in premature serum.
- CR2 ligands modulate human B cell activation.
- Effect of fibronectin on IgA-mediated uptake of type III group B streptococci by phagocytes.
- Mechanisms of tumor necrosis factor-alpha alteration of PMN adhesion and migration.
- Group B streptococci inactivate complement component C5a by enzymic cleavage at the C-terminus.
- Human neutrophil adherence to laminin in vitro. Evidence for a distinct neutrophil integrin receptor for laminin.
- Purification of the proteinase from group B streptococci that inactivates human C5a.
- Bacterial evasion of the antibody response: human IgG antibodies neutralize soluble but not bacteria-associated group B streptococcal C5a-ase.
- Comparison of the opsonic and complement triggering activity of human monoclonal IgG1 and IgM antibody against group B streptococci.
- Divalent cation substitution reveals CD18- and very late antigen-dependent pathways that mediate human neutrophil adherence to fibronectin.
- CD11/CD18-independent neutrophil adherence to laminin is mediated by the integrin VLA-6.
- Evidence for a conformational change in human fibronectin which occurs between 4 and 37 degrees C.
- Demonstration of defective C3-receptor-mediated clearance by the reticuloendothelial system in patients with acquired immunodeficiency Syndrome.
- The role of the spleen in resistance to infection.
- Fibronectin-enhanced phagocytosis of an alternative pathway activator by human culture-derived macrophages is mediated by the C4b/C3b complement receptor (CR1).
- Connective tissue proteins and phagocytic cell function. Laminin enhances complement and Fc-mediated phagocytosis by cultured human macrophages.
- Genetic relatedness between group B streptococci originating from bovine mastitis and a human group B Streptococcus type V cluster displaying an identical pulsed-field...
- Association of two functional polymorphisms in the CCR5 gene with juvenile rheumatoid Arthritis.
- Juvenile idiopathic Arthritis and exposure to fine particulate air pollution.
- Natural killer cell lymphoma in a pediatric patient with inflammatory bowel Disease.
- The susceptibility loci juvenile idiopathic Arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1.
- Treatment approaches to juvenile dermatomyositis (JDM) across North America: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) JDM Treatment Survey.
- Anakinra for systemic juvenile Arthritis: the Rocky Mountain experience.
- Evaluation of genetic association between an ITGAM non-synonymous SNP (rs1143679) and multiple autoimmune Diseases.
- Sclerosing mesenteritis in a child with celiac Disease.
- Adalimumab with or without methotrexate in juvenile rheumatoid Arthritis.
- A 6-year-old child with Fever of unknown origin, anemia, and abdominal Pain.
- Familial aggregation of juvenile idiopathic Arthritis.
- Clonality analysis after retroviral-mediated gene transfer to CD34+ cells from the cord blood of ADA-deficient SCID neonates.
- Long-term efficacy of enzyme replacement therapy for adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID).
- Equivalence of high-virulence clonotypes of serotype III group B Streptococcus agalactiae (GBS).
Schools
University of Virginia Main Campus
University of Washington
Procedures Preformed
- Joint Drainage
Conditions Treated
- Amyloidosis
- Ankylosing Spondylitis
- Antiphospholipid Syndrome (APS)
- Arthritis
- View All
Doctors Specialties
- Pediatric Rheumatology
Accepted Insurances
Awards
- Regional Top Doctor
- Top MD
- Fellow
Education
-
University of Virginia School of Medicine
Hospital
-
University of Utah Health Care - Hospital and Clinics
Helpful Reviews
Similar Doctors
|
Dr. Leonard L. Dragone, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Aimee O. Hersh, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Sara M. Stern, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Andrew S. Zeft, MD |