Physician
Family Medicine
Dr. John E. Hearst, MD
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Doctor John E. Hearst, MD works in the field of Family Medicine. He studied medicine at George Washington University School of Medicine. George Washington University School of Medicine has a rank of 67 in research and a 0 in primary care John Hearst is also a published physician. He has 101 paper published. The most recent paper is: Rhodobacter capsulatus DNA topoisomerase I purification and characterization. He is registered with Medicare.
Publications
- Quantitative analysis of DNA interstrand cross-links and monoadducts formed in human cells induced by psoralens and UVA irradiation.
- LC-MS/MS for the detection of DNA interstrand cross-links formed by 8-methoxypsoralen and UVA irradiation in human cells.
- Stem cell transplantation with S-59 photochemically treated T-cell add-backs to establish allochimerism in murine thalassemia.
- DNA repair defects channel interstrand DNA cross-links into alternate recombinational and error-prone repair pathways.
- Allogeneic T cells treated with amotosalen prevent lethal cytomegalovirus disease without producing graft-versus-host disease following bone marrow transplantation.
- Photochemical treatment of donor lymphocytes inhibited their ability to facilitate donor engraftment or increase donor chimerism after nonmyeloablative conditioning or...
- Recombinational and mutagenic repair of psoralen interstrand cross-links in Saccharomyces cerevisiae.
- The crystal structures of psoralen cross-linked DNAs: drug-dependent formation of Holliday junctions.
- DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts.
- Three ways to be a saber-toothed cat.
- Photochemical treatment with S-59 psoralen and ultraviolet A light to control the fate of naive or primed T lymphocytes in vivo after allogeneic bone marrow transplant...
- Rhodobacter capsulatus DNA topoisomerase I purification and characterization.
- A simple mechanism for the avoidance of entanglement during chromosome replication.
- Gender differences in the relations between depressive symptoms and drinking behavior among problem drinkers: a three-wave study.
- Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long-wavelength ultraviolet light.
- The local repressor AcrR plays a modulating role in the regulation of acrAB genes of Escherichia coli by global stress signals.
- Carotenoids 2: Genetics and molecular biology of carotenoid pigment biosynthesis.
- Laser-induced protein-DNA cross-links via psoralen furanside monoadducts.
- Evolutionary conservation and structural similarities of carotenoid biosynthesis gene products from photosynthetic and nonphotosynthetic organisms.
- The Rhodobacter capsulatus chlorin reductase-encoding locus, bchA, consists of three genes, bchX, bchY, and bchZ.
- Analysis of the promoter and regulatory sequences of an oxygen-regulated bch operon in Rhodobacter capsulatus by site-directed mutagenesis.
- Molecular matchmakers.
- Psoralens and their application to the study of some molecular biological processes.
- In vitro expression and activity of lycopene cyclase and beta-carotene hydroxylase from Erwinia herbicola.
- DNA repair by eukaryotic nucleotide excision nuclease. Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevi...
- Molecular cloning and characterization of acrA and acrE genes of Escherichia coli.
- bchFNBH bacteriochlorophyll synthesis genes of Rhodobacter capsulatus and identification of the third subunit of light-independent protochlorophyllide reductase in bac...
- Polymer models for interphase chromosomes.
- Early evolution of photosynthesis: clues from nitrogenase and chlorophyll iron proteins.
- Regulation of carotenoid and bacteriochlorophyll biosynthesis genes and identification of an evolutionarily conserved gene required for bacteriochlorophyll accumulation.
- Introduction of new carotenoids into the bacterial photosynthetic apparatus by combining the carotenoid biosynthetic pathways of Erwinia herbicola and Rhodobacter spha...
- Efficient anchoring of RNA polymerase in Escherichia coli during coupled transcription-translation of genes encoding integral inner membrane polypeptides.
- Mutagenesis of the hairpin ribozyme.
- Chromosome condensation: amorphous or structured.
- Luminescence energy transfer using a terbium chelate: improvements on fluorescence energy transfer.
- DNA structural reorganization upon conversion of a psoralen furan-side monoadduct to an interstrand cross-link: implications for DNA repair.
- Efflux pumps and drug resistance in gram-negative bacteria.
- Functional assignment of Erwinia herbicola Eho10 carotenoid genes expressed in Escherichia coli.
- A random-walk/giant-loop model for interphase chromosomes.
- Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli.
- The structure of photolyase: using photon energy for DNA repair.
- Identifying the killer in cystic fibrosis.
- Spin-labeled psoralen probes for the study of DNA dynamics.
- Evidence for the organization of chromatin in megabase pair-sized loops arranged along a random walk path in the human G0/G1 interphase nucleus.
- Solution structures of psoralen monoadducted and cross-linked DNA oligomers by NMR spectroscopy and restrained molecular dynamics.
- Structure and topology of 16S ribosomal RNA. An analysis of the pattern of psoralen crosslinking.
- Characterization of murine lung and peritoneal macrophages.
- Characterization of the photoreaction between DNA and aminomethyl-trimethylpsoralen using absorption and fluorescence spectroscopy.
- Interactions of daunomycin and melanotropin-daunomycin with DNA.
- Psoralen photochemistry and nucleic acid structure.
- Low-level psoralen--deoxyribonucleic acid cross-links induced by single laser pulses.
- Kinetics of formation of deoxyribonucleic acid cross-links by 4'-(aminomethyl)-4,5',8-trimethylpsoralen.
- Structure of a psoralen-thymine monoadduct formed in photoreaction with DNA.
- Dose-related effects of psoralen and ultraviolet light on the cell cycle of murine melanoma cells.
- Psoralen-deoxyribonucleic acid photoreaction. Characterization of the monoaddition products from 8-methoxypsoralen and 4,5'8-trimethylpsoralen.
- Fine mapping of secondary structures of fd phage DNA in the region of the replication origin.
- Escherichia coli deoxyribonucleic acid dependent ribonucleic acid polymerase transcriptional pause sites on SV40 DNA F1.
- Photoaddition of trimethylpsoralen as a probe for the intracellular organization of Escherchia coli DNA.
- Two types of replication proteins increase the rate at which T4 DNA polymerase traverses the helical regions in a single-stranded DNA template.
- Determination of the secondary structure of Drosophila melanogaster 5 S RNA by hydroxymethyltrimethylpsoralen crosslinking.
- Nucleotide and deduced polypeptide sequences of the photosynthetic reaction-center, B870 antenna, and flanking polypeptides from R. capsulata.
- 8-Methoxypsoralen-nucleic acid photoreaction. Effect of methyl substitution on pyrone vs. furan photoaddition.
- Sharp kink of DNA at psoralen-cross-link site deduced from crystal structure of psoralen-thymine monoadduct.
- Resistance of the scrapie agent to inactivation by psoralens.
- The reaction of the psoralens with deoxyribonucleic acid.
- Structure-function relations in E. coli 16S RNA.
- Size of the unwound region of DNA in Escherichia coli RNA polymerase and calf thymus RNA polymerase II ternary complexes.
- Isolation and characterization of enhanced fluorescence mutants of Rhodopseudomonas capsulata.
- Tn5.7 construction and physical mapping of pRPS404 containing photosynthetic genes from Rhodopseudomonas capsulata.
- Initiation of RNA synthesis in vitro by vesicular stomatitis virus: single internal initiation in the presence of aurintricarboxylic acid and vanadyl ribonucleoside co...
- R-prime site-directed transposon Tn7 mutagenesis of the photosynthetic apparatus in Rhodopseudomonas capsulata.
- A topological model for transcription based on unwinding angle analysis of E. coli RNA polymerase binary, initiation and ternary complexes.
- Identification of a site of psoralen crosslinking in E. coli 16S ribosomal RNA.
- Identification of a structural hairpin in the filamentous chimeric phage M13Gori1.
- Interaction of psoralen derivatives with the RNA genome of Rous sarcoma virus.
- Pauses at positions of secondary structure during in vitro replication of single-stranded fd bacteriophage DNA by T4 DNA polymerase.
- Termination sites of the in vitro nick-translation reaction on DNA that had photoreacted with psoralen.
- Structure of E. coli 16S RNA elucidated by psoralen crosslinking.
- Dependence of 4'-(hydroxymethyl)-4,5',8-trimethylpsoralen photoaddition on the conformation of ribonucleic acid.
- Specificity of the photoreaction of 4'-(hydroxymethyl)-4,5',8-trimethylpsoralen with ribonucleic acid. Identification of reactive sites in Escherichia coli phenylalani...
- Sequencing psoralen photochemically reactive sites in Escherichia coli 16 S rRNA.
- Identification of the modified nucleotides produced by covalent photoaddition of hydroxymethyltrimethylpsoralen to RNA.
- Psoralen photochemistry.
- A sequence from Drosophila melanogaster 18S rRNA bearing the conserved hypermodified nucleoside am psi: analysis by reverse transcription and high-performance liquid c...
- Efficient formation of a crosslinkable HMT monoadduct at the Kpn I recognition site.
- Genetic-physical mapping of a photosynthetic gene cluster from R. capsulata.
- Photochemistry of the furan-side 8-methoxypsoralen-thymidine monoadduct inside the DNA helix. Conversion to diadduct and to pyrone-side monoadduct.
- Purification of circular DNA using benzoylated naphthoylated DEAE-cellulose.
- Sites of termination of in vitro DNA synthesis on psoralen phototreated single-stranded templates.
- A putative nitrogenase reductase gene found in the nucleotide sequences from the photosynthetic gene cluster of R. capsulata.
- Reverse Southern hybridization.
- Thermostability of double-stranded deoxyribonucleic acids: effects of covalent additions of a psoralen.
- Wavelength dependence for the photoreversal of a psoralen-DNA cross-link.
- A theoretical study of the effects of driven motion on rotational correlations of biological systems.
- Wavelength dependence for the photoreactions of DNA-psoralen monoadducts. 2. Photo-cross-linking of monoadducts.
- Wavelength dependence for the photoreactions of DNA-psoralen monoadducts. 1. Photoreversal of monoadducts.
- Action mechanism of ABC excision nuclease on a DNA substrate containing a psoralen crosslink at a defined position.
- Regulation of expression of genes for light-harvesting antenna proteins LH-I and LH-II; reaction center polypeptides RC-L, RC-M, and RC-H; and enzymes of bacteriochlor...
- Solution hybridization of crosslinkable DNA oligonucleotides to bacteriophage M13 DNA. Effect of secondary structure on hybridization kinetics and equilibria.
- The effects of covalent additions of a psoralen on transcription by E. coli RNA polymerase.
Schools
George Washington University School Of Medicine
St Marys Hospital University Wisc
University Of Wisconsin Madison
Doctors Specialties
- Family Medicine
Accepted Insurances
- Choice Plus POS II
- Blue Card PPO
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- Open Access Plus
- Empire Blue Cross Blue Shield HMO
- Harvard Pilgrim Health Care PPO
- Medicare MCR
Education
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George Washington University School of Medicine
Drug Facts
| NPI NUMBER | 1972553766 | |
| NPPES Provider LastName | HEARST | |
| NPPES Provider FirstName | JOHN | |
| NPPES Provider ZIPCode | 052015009 | |
| NPPES Provider State | VT | |
| Specialty Description | Family Practice | |
| Total Claim Count | 556.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1972553766 |
| Last Name Of The Provider | HEARST |
| First Name Of The Provider | JOHN |
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