Associate Professor, Chief, Pediatric Cardiology
Pediatric Cardiology
Dr. John C. Ralphe, MD
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John C. Ralphe practices Pediatric Cardiology. He attended State University of New York Downstate Medical Center College of Medicine. John Ralphe is a published doctor. He published 21 publications, including: 'Cardiac MyBP-C regulates the rate and force of contraction in mammalian myocardium.'
Publications
- Ablation of cardiac myosin-binding protein-C accelerates contractile kinetics in engineered cardiac tissue.
- Cardiac MyBP-C regulates the rate and force of contraction in mammalian myocardium.
- Pompe Disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes.
- Neonatal mouse-derived engineered cardiac tissue: a novel model system for studying genetic heart Disease.
- E258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction.
- Just sinus bradycardia or something more serious?
- 3D engineered cardiac tissue models of human heart Disease: Learning more from our mice.
- Exercise restrictions after balloon Aortic valvuloplasty.
- Ultrastructural, immunofluorescence, and RNA evidence support the hypothesis of a "new" virus associated with Kawasaki Disease.
- A three-dimensional gel bioreactor for assessment of cardiomyocyte induction in skeletal muscle-derived stem cells.
- An unexpected cause of chronic dysphonia in a 10-year-old boy.
- Pediatric cardiologists can accurately use physical examination to identify pathologic murmurs in neonates.
- Modest maternal caffeine exposure affects developing embryonic cardiovascular function and growth.
- Neonatal congestive Heart failure due to a subclavian artery to subclavian vein fistula diagnosed by noninvasive procedures.
- Myocardial vascular and metabolic adaptations in chronically anemic fetal sheep.
- Regulation of myocardial glucose transporters GLUT1 and GLUT4 in chronically anemic fetal lambs.
- Correlation between myocardial malate/aspartate shuttle activity and EAAT1 protein expression in hyper- and hypothyroidism.
- Ontogeny of vascular growth factors in perinatal sheep myocardium.
- Localization and function of the brain excitatory amino acid transporter type 1 in cardiac mitochondria.
- Metabolic adaptation of the fetal and postnatal ovine Heart: regulatory role of hypoxia-inducible factors and nuclear respiratory factor-1.
Schools
SUNY Downstate Medical Center College Of Medicine
University Iowa Hosps and Clins
Procedures Preformed
- Cardiac Imaging
Conditions Treated
- Aortic Ectasia
- Aortic Valve Disease
- Arrhythmias (incl. Atrial Fibrillation)
- Coarctation of the Aorta
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Doctors Specialties
- Pediatric Cardiology
Accepted Insurances
Education
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University of Iowa Hospitals and Clinics -
State University of New York Downstate Medical Center College of Medicine
Hospital
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University of Wisconsin Hospital and Clinics
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