Professor, Internal Medicine, Mayo Medical School
Endocrinology
Dr. Johannes D. Veldhuis, MD
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Johannes D. Veldhuis, MD works in the field of Endocrinology. He went to Penn State College of Medicine. He over the years received 1 awards: "Elected Member". Johannes Veldhuis is a published MD. He published 101 publications, including: 'Proinflammatory Cytokine Infusion Attenuates LH's Feedforward on Testosterone Secretion: Modulation by Age.'
Publications
- Proinflammatory Cytokine Infusion Attenuates LH's Feedforward on Testosterone Secretion: Modulation by Age.
- Subcutaneous infusion of kisspeptin-54 stimulates gonadotrophin release in women and the response correlates with basal oestradiol levels.
- Somatostatin Is Essential for the Sexual Dimorphism of GH Secretion, Corticosteroid-Binding Globulin Production, and Corticosterone Levels in Mice.
- Estrogen-Like Potentiation of Ghrelin-Stimulated GH Secretion by Fulvestrant, a Putatively Selective ER Antagonist, in Postmenopausal Women.
- An early reduction in GH peak amplitude in preproghrelin deficient male mice has a minor impact on linear growth.
- Distinct roles of age and abdominal visceral fat in reducing androgen receptor-dependent negative feedback on LH secretion in healthy men.
- Immunologic and mass-spectrometric estimates of SHBG concentrations in healthy women.
- Thyrotropin secretion in healthy subjects is robust and independent of age and gender, and only weakly dependent on body mass index.
- Estradiol, but not Testosterone, Heightens Cortisol-Mediated Negative Feedback on Pulsatile ACTH Secretion and ACTH Approximate Entropy.
- Corticotropic axis drive of overnight cortisol secretion is suppressed in adolescents and young adults with type 1 Diabetes mellitus.
- Development of a methodology for and assessment of pulsatile luteinizing hormone secretion in juvenile and adult male mice.
- Growth hormone secretion is correlated with neuromuscular innervation rather than motor neuron number in early-symptomatic male amyotrophic lateral sclerosis mice.
- Short-Term Estradiol Supplementation Potentiates Low-Dose Ghrelin Action in the Presence of GHRH or Somatostatin in Older Women.
- Gender determines ACTH recovery from hypercortisolemia in healthy older humans.
- Age-dependent and gender-dependent regulation of hypothalamic-adrenocorticotropic-adrenal axis.
- Changes in pituitary function with ageing and implications for patient care.
- Sex Steroids, GHRH, Somatostatin, IGF-I, and IGFBP-1 Modulate Ghrelin's Dose-Dependent Drive of Pulsatile GH Secretion in Healthy Older Men.
- The Decline in Pulsatile GH Secretion throughout Early Adulthood in Mice Is Exacerbated by Dietary-Induced Weight Gain.
- Distinct Metabolic Surrogates Predict Basal and Rebound GH Secretion after Glucose Ingestion in Men.
- Glucose Ingestion Acutely Lowers Pulsatile LH and Basal Testosterone Secretion in Men.
- Noninvasive Analytical Estimation of Endogenous GnRH Drive: Analysis Using Graded Competitive GnRH-Receptor Antagonism and a Calibrating Pulse of Exogenous GnRH.
- Older Men Exhibit Reduced Efficacy of and Heightened Potency Downregulation by Intravenous Pulses of Recombinant Human LH: a study in 92 healthy men.
- Endogenous ACTH Concentration-Cortisol Secretion Dose Analysis Unmasks Decreased ACTH Potency in Cushing's Disease with Restoration after Successful Pituitary Adenomec...
- Oscillations in Joint Synchrony of Reproductive Hormones in Healthy Men.
- Regulated recovery of pulsatile growth-hormone secretion from negative feedback: a preclinical investigation.
- Tripartite Control of Dynamic ACTH-Cortisol Dose Responsiveness by Age, Body Mass Index, and Gender in 111 Healthy Adults.
- Glucose Ingestion Selectively Amplifies ACTH and Cortisol Secretory-Burst Mass and Enhances Their Joint Synchrony in Healthy Men.
- Loss of Inverse Relationship Between Pulsatile Insulin and Glucagon Secretion in Patients With Type 2 Diabetes.
- Impaired adrenergic- and corticotropic-axis outflow during exercise in chronic obstructive pulmonary disease.
- Gender, Sex-Steroid, and Secretagogue-Selective Recovery from Growth Hormone-Induced Feedback in Older Women and Men.
- Overnight ACTH-Cortisol Dose-Responsiveness: comparison with 24-hr data, metyrapone administration, and insulin-tolerance test in healthy adults.
- Complex Regulation of GH Autofeedback under Dual-Peptide Drive: studies under a pharmacological GH and sex-steroid clamp.
- Analytical construct of reversible desensitization of pituitary-testicular signaling: illustrative application in aging.
- Altered multihormone synchrony in obese patients with polycystic ovary Syndrome.
- Gender, age, body mass index, and IGF-I individually and jointly determine distinct GH dynamics: analyses in one hundred healthy adults.
- Effects of testosterone administration on nocturnal cortisol secretion in healthy older men.
- Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men.
- A pegylated growth hormone receptor antagonist, pegvisomant, does not enter the brain in humans.
- Dose-response downregulation within the span of single interpulse intervals.
- Age in men does not determine gonadotropin-releasing hormone's dose-dependent stimulation of luteinizing hormone secretion under an exogenous testosterone clamp.
- Rapid glucocorticoid receptor-mediated inhibition of hypothalamic-pituitary-adrenal ultradian activity in healthy males.
- Dynamic characteristics of blood glucose time series during the course of critical illness: effects of intensive insulin therapy and relative association with mortality.
- A super-agonist of growth hormone-releasing hormone causes rapid improvement of nutritional status in patients with chronic kidney disease.
- Thyrotropin secretion in mild and severe primary Hypothyroidism is distinguished by amplified burst mass and Basal secretion with increased spikiness and approximate e...
- Pre- versus postmenopausal age, estradiol, and peptide-secretagogue Type determine pulsatile growth hormone secretion in healthy women: studies using submaximal agonis...
- Age-dependent regression analysis of male gonadal axis.
- Testosterone's short-term positive effect on luteinizing-hormone secretory-burst mass and its negative effect on secretory-burst frequency are attenuated in middle-age...
- Basal, pulsatile, entropic (patterned), and spiky (staccato-like) properties of ACTH secretion: impact of age, gender, and body mass index.
- Thyrotropin secretion profiles are not different in men and women.
- Acute effects of testosterone infusion on the serum luteinizing hormone profile in eumenorrheic and polycystic ovary Syndrome adolescents.
- Relative effects of estrogen, age, and visceral fat on pulsatile growth hormone secretion in healthy women.
- Sensitivity and specificity of pulse detection using a new deconvolution method.
- Regulation of basal, pulsatile, and entropic (patterned) modes of GH secretion in a putatively low-somatostatin milieu in women.
- Sex defines the age dependence of endogenous ACTH-cortisol dose responsiveness.
- Factors other than sex steroids modulate GHRH and GHRP-2 efficacies in men: evaluation using a GnRH agonist/testosterone clamp.
- Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and ...
- Diminished and irregular thyrotropin secretion with preserved diurnal rhythm in patients with active acromegaly.
- Determinants of GH-releasing hormone and GH-releasing peptide synergy in men.
- Quantifying nonlinear interactions within the hypothalamo-pituitary-adrenal axis in the conscious horse.
- Aromatase and 5alpha-reductase inhibition during an exogenous testosterone clamp unveils selective sex steroid modulation of somatostatin and growth hormone secretagog...
- Pituitary-hormone secretion by thyrotropinomas.
- Testosterone supplementation in older men restrains insulin-like growth factor's dose-dependent feedback inhibition of pulsatile growth hormone secretion.
- Motivations and methods for analyzing pulsatile hormone secretion.
- Effects of continuous versus intermittent exercise, obesity, and gender on growth hormone secretion.
- Estrogen elevates the peak overnight production rate of acylated ghrelin.
- Estradiol supplementation in postmenopausal women attenuates suppression of pulsatile growth hormone secretion by recombinant human insulin-like growth factor Type I.
- Thyrotropin secretion by thyrotropinomas is characterized by increased pulse frequency, delayed diurnal rhythm, enhanced basal secretion, spikiness, and disorderliness.
- Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and beta-cell mass to age-related insulin resistance in rats.
- Estrogen supplementation selectively enhances hypothalamo-pituitary sensitivity to ghrelin in postmenopausal women.
- Measurement of pulsatile insulin secretion in the rat: direct sampling from the hepatic portal vein.
- Twenty-four hour continuous ghrelin infusion augments physiologically pulsatile, nycthemeral, and entropic (feedback-regulated) modes of growth hormone secretion.
- Growth hormone (GH) secretion, GH-dependent gene expression, and sexually dimorphic body growth in young rats with chronic renal failure.
- Altered growth hormone, cortisol, and leptin secretion in healthy elderly persons with sarcopenia and mixed body composition phenoTypes.
- Pituitary and/or peripheral estrogen-receptor alpha regulates follicle-stimulating hormone secretion, whereas central estrogenic pathways direct growth hormone and pro...
- Gonadal status and body mass index jointly determine growth hormone (GH)-releasing hormone/GH-releasing peptide synergy in healthy men.
- Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells.
- A noninvasive measure of negative-feedback strength, approximate entropy, unmasks strong diurnal variations in the regularity of LH secretion.
- Peripheral estrogen receptor-alpha selectively modulates the waveform of GH secretory bursts in healthy women.
- Long-term testosterone supplementation augments overnight growth hormone secretion in healthy older men.
- Putative somatostatin suppression potentiates adrenocorticotropin secretion driven by ghrelin and human corticotropin-releasing hormone.
- Age attenuates testosterone secretion driven by amplitude-varying pulses of recombinant human luteinizing hormone during acute gonadotrope inhibition in healthy men.
- Estimation of the size and shape of GH secretory bursts in healthy women using a physiological estradiol clamp and variable-waveform deconvolution model.
- Tripartite control of growth hormone secretion in women during controlled estradiol repletion.
- Model-projected mechanistic bases for sex differences in growth hormone regulation in humans.
- Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets.
- Age or factors associated with aging attenuate testosterone's concentration-dependent enhancement of the regularity of luteinizing hormone secretion in healthy men.
- Estradiol potentiates ghrelin-stimulated pulsatile growth hormone secretion in postmenopausal women.
- Mechanisms of impaired fasting glucose and glucose intolerance induced by an approximate 50% pancreatectomy.
- Intrahepatic transplanted islets in humans secrete insulin in a coordinate pulsatile manner directly into the liver.
- Effect of pioglitazone on glucose metabolism and luteinizing hormone secretion in women with polycystic ovary Syndrome.
- An ensemble model of the male gonadal axis: illustrative application in aging men.
- Ghrelin potentiates growth hormone secretion driven by putative somatostatin withdrawal and resists inhibition by human corticotropin-releasing hormone.
- Active acromegaly enhances spontaneous parathyroid hormone pulsatility.
- Growth hormone response to graded exercise intensities is attenuated and the gender difference abolished in older adults.
- Disordered adrenocorticotropin secretion in women with major depression.
- Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion: further evidence for the intraislet insulin hypothesis.
- Somatotropic and gonadotropic axes linkages in infancy, childhood, and the puberty-adult transition.
- Relationship between beta-cell mass and fasting blood glucose concentration in humans.
- A novel functional interaction between the Sp1-like protein KLF13 and SREBP-Sp1 activation complex underlies regulation of low density lipoprotein receptor promoter fu...
- Aging attenuates both the regularity and joint synchrony of LH and testosterone secretion in normal men: analyses via a model of graded GnRH receptor blockade.
Schools
Pennsylvania State University College Of Medicine
Mayo Grad School Med
Penn State
Conditions Treated
- Cushing's Syndrome
- Diabetes Type 2
- Hyposmolality and Hyponatremia
- Hypothyroidism
Doctors Specialties
- Endocrinology
Accepted Insurances
- Choice Plus POS II
- Altius Health Plans
- Blue Card PPO
- Blue Cross Blue Shield of Illinois PPO
- Blue Cross Accord
- Blue Cross of Idaho PPO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- Open Access Plus
- First Health (Coventry Health Care) PPO
- Choice Care PPO
- LifeWise
- MultiPlan PPO
- PHCS Network PPO
- ODS Health Plan
- Heritage Signature
- Choice Plus POS
- Navigate POS
- Options PPO
Awards
- Elected Member
Education
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Penn State University -
Mayo School of Graduate Medical Education -
Penn State College of Medicine
Hospital
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Mayo Clinic - Rochester, Minnesota
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1477530335 |
| Last Name Of The Provider | VELDHUIS |
| First Name Of The Provider | JOHANNES |
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