Division Chief of Oncology, Professor of Pediatrics, Children's Hosp of Michigan, Wayne State Univer
Pediatric Hematology & Oncology
Dr. Jeffrey W. Taub, MD
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Jeffrey Taub works in the field of Pediatric Hematology & Oncology. He over the years received 3 awards: "Regional Top Doctor", "Fellow (FAAP)" and "Super Doctor". Doctor Jeffrey W. Taub, MD is a published MD. He published 91 publications, including: 'Factors in improved survival from paediatric cancer.'
Publications
- Synergistic anti-leukemic interactions between panobinostat and MK-1775 in Acute myeloid leukemia ex vivo.
- Obatoclax potentiates the cytotoxic effect of cytarabine on Acute myeloid leukemia cells by enhancing DNA damage.
- Targeting histone deacetylases (HDACs) and Wee1 for treating high-risk neuroblastoma.
- Prognosis and management of Acute myeloid leukemia in patients with Down syndrome.
- Prognostic factors in children with Acute myeloid leukaemia and excellent response to remission induction therapy.
- Targeting the wee1 kinase for treatment of pediatric Down syndrome Acute myeloid leukemia.
- Temperament, personality, and quality of life in pediatric cancer patients.
- AAML0523: A report from the Children's Oncology Group on the efficacy of clofarabine in combination with cytarabine in pediatric patients with recurrent Acute myeloid ...
- New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell Acute lymphoblastic leukemia.
- Parent Caregiver Self-Efficacy and Child Reactions to Pediatric Cancer Treatment Procedures.
- Gemtuzumab ozogamicin can reduce minimal residual disease in patients with childhood Acute myeloid leukemia.
- Longitudinal study of parent caregiving self-efficacy and parent stress reactions with pediatric cancer treatment procedures.
- Prognostic features in Acute megakaryoblastic leukemia in children without Down syndrome: a report from the AML02 multicenter trial and the Children's Oncology Group S...
- Effect of body mass index on the outcome of children with Acute myeloid leukemia.
- Valproic acid synergistically enhances the cytotoxicity of clofarabine in pediatric Acute myeloid leukemia cells.
- What's up with down syndrome and Leukemia-A lot!
- Acute megakaryoblastic leukemia without GATA1 mutation after transient myeloproliferative disorder in an infant without Down syndrome.
- A Unique Role of GATA1s in Down Syndrome Acute Megakaryocytic Leukemia Biology and Therapy.
- Mechanisms of synergistic antileukemic interactions between valproic acid and cytarabine in pediatric Acute myeloid leukemia.
- Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome.
- RUNX1 regulates phosphoinositide 3-kinase/AKT pathway: role in chemotherapy sensitivity in Acute megakaryocytic leukemia.
- Down syndrome and Malignancies: a unique clinical relationship: a paper from the 2008 william beaumont hospital symposium on molecular pathology.
- Insights on chronic-relapsing opsoclonus-myoclonus from a pilot study of mycophenolate mofetil.
- 5,10-methylenetetrahydrofolate reductase (MTHFR) polymorphisms and the risk of Acute lymphoblastic leukemia (ALL) in Filipino children.
- Children with hyperdiploid but not triple trisomy (+4,+10,+17) Acute lymphoblastic leukemia have an increased incidence of extramedullary relapse on current therapies:...
- Association between prenatal pesticide exposures and the generation of Leukemia-associated T(8;21).
- Prognostic role of the reduced folate carrier, the major membrane transporter for methotrexate, in childhood Acute lymphoblastic leukemia: a report from the Children's...
- Risk for Leukemia in infants without Down syndrome who have transient myeloproliferative disorder.
- Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic Leukemia.
- Transcriptional regulation of the human reduced folate carrier in childhood Acute lymphoblastic leukemia cells.
- GATA1, cytidine deaminase, and the high cure rate of Down syndrome children with Acute megakaryocytic leukemia.
- Down syndrome, drug metabolism and chromosome 21.
- Prenatal origin of GATA1 mutations may be an initiating step in the development of megakaryocytic Leukemia in Down syndrome.
- Primary Acute lymphoblastic leukemia cells use a novel promoter and 5'noncoding exon for the human reduced folate carrier that encodes a modified carrier translated fr...
- Retroperitoneal malignant peripheral nerve sheath tumor: evaluation with serial FDG-PET.
- The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and Leukemia cell lines.
- Physical and functional interactions between USF and Sp1 proteins regulate human deoxycytidine kinase promoter activity.
- Transcriptional regulation of the cystathionine-beta -synthase gene in Down syndrome and non-Down syndrome megakaryocytic Leukemia cell lines.
- High frequency of leukemic clones in newborn screening blood samples of children with B-precursor Acute lymphoblastic leukemia.
- Down syndrome and the transient Myeloproliferative disorder: why is it transient?
- Posttraumatic Stress Symptoms in Parents of Pediatric Cancer Patients: A Mediational Analysis.
- Panobinostat synergistically enhances the cytotoxic effects of cisplatin, doxorubicin or etoposide on high-risk neuroblastoma Cells.
- Panobinostat Enhances Cytarabine and Daunorubicin Sensitivities in AML Cells through Suppressing the Expression of BRCA1, CHK1, and Rad51.
- Overexpression of GATA1 Confers Resistance to Chemotherapy in Acute Megakaryocytic Leukemia.
- Efficient self-assembly of human papillomavirus type 16 L1 and L1-L2 into virus-like particles.
- Natural history of transient Myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the Children's Oncology Group Study A2971.
- Unique clinical and biological features of Leukemia in Down syndrome children.
- Minimal residual disease-directed therapy for childhood Acute myeloid leukaemia: results of the AML02 multicentre trial.
- The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell Acute lymphoblastic leukemia: a report from the Children''s Onc...
- Prenatal origin of childhood Acute lymphoblastic leukemia, association with birth weight and hyperdiploidy.
- Identification and characterization of novel AML1-ETO fusion transcripts in pediatric t(8;21) Acute myeloid leukemia: a report from the Children''s Oncology Group.
- The role of the proto-oncogene ETS2 in Acute megakaryocytic leukemia biology and therapy.
- The GATA site-dependent hemogen promoter is transcriptionally regulated by GATA1 in hematopoietic and Leukemia cells.
- Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the Hi...
- Congenital microangiopathic hemolytic Anemia and thrombocytopenia with unusually large von Willebrand factor multimers and von Willebrand factor-cleaving protease.
- Transcriptional regulation of Cell-specific expression of the human cystathionine beta -synthase gene by differential binding of Sp1/Sp3 to the -1b promoter.
- Transcriptional regulation of the human cystathionine beta-synthase -1b basal promoter: synergistic transactivation by transcription factors NF-Y and Sp1/Sp3.
- Relationship of p15 and p16 gene alterations to elevated dihydrofolate reductase in childhood Acute lymphoblastic leukaemia.
- Relationship of chromosome 21 and Acute leukemia in children with Down syndrome.
- Hepatoblastoma with spinal metastases.
- Cystathionine-beta-synthase cDNA transfection alters the sensitivity and metabolism of 1-beta-D-arabinofuranosylcytosine in CCRF-CEM Leukemia cells in vitro and in viv...
- Molecular and cellular correlates of methotrexate response in childhood Acute lymphoblastic leukemia.
- Down syndrome and Acute myeloid leukemia. Lessons learned from experience with high-dose Ara-C containing regimens.
- Expression of chromosome 21-localized genes in Acute myeloid leukemia: differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro...
- Factors in improved survival from paediatric cancer.
- Reduced folate carrier gene expression in childhood Acute lymphoblastic leukemia: relationship to immunophenotype and ploidy.
- Down syndrome and Leukemia--an overview of cytogenetic and molecular events.
- Confocal microscopy visualization of antifolate uptake by the reduced folate carrier in human leukaemic Cells.
- Myeloblasts from Down syndrome children with Acute myeloid leukemia have increased in vitro sensitivity to cytosine arabinoside and daunorubicin.
- Increased frequency of expression of elevated dihydrofolate reductase in T-cell versus B-precursor Acute lymphoblastic leukemia in children.
- Methotrexate pharmacology and resistance in childhood Acute lymphoblastic leukemia.
- Treatment of childhood Acute myeloid leukaemia.
- Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome Cells: a contributing factor to the superior event free survival of Down syndrome children wi...
- Renal Cell carcinoma occurring in a child 2 years after chemotherapy for neuroblastoma.
- Acute lymphoblastic leukemia in a 46,XY/47,XYY mosaic male: clonal origin of leukemia in the XY-bearing stem-cell line.
- Role of USF1 in the differential expression of the human deoxycytidine kinase gene in Acute myeloid leukemia.
- Characterization of autoantibodies against the platelet glycoprotein antigens IIb/IIIa in childhood idiopathic thrombocytopenia purpura.
- Elevated dihydrofolate reductase and impaired methotrexate transport as elements in methotrexate resistance in childhood Acute lymphoblastic leukemia.
- Polymorphisms in methylenetetrahydrofolate reductase and methotrexate sensitivity in childhood Acute lymphoblastic leukemia.
- High frequency of the 844ins68 cystathionine-beta-synthase gene variant in Down syndrome children with Acute myeloid leukemia.
- Role of the E45K-reduced folate carrier gene mutation in methotrexate resistance in human Leukemia cells.
- Synergistic regulation of human cystathionine-beta-synthase-1b promoter by transcription factors NF-YA isoforms and Sp1.
- Elevated serum cobalamin levels in childhood autoimmune and drug-induced Neutropenia.
- The prenatal origin of childhood Acute lymphoblastic leukemia.
- Parent communication and child pain and distress during painful pediatric cancer treatments.
- A prospective study of the natural history of transient Leukemia (TL) in neonates with Down syndrome (DS): Children's Oncology Group (COG) study POG-9481.
- Transcription factor GATA-1 and Down syndrome leukemogenesis.
- Early T-cell precursor Acute lymphoblastic leukaemia.
- Cardiomyopathy in children with Down syndrome treated for Acute myeloid leukemia: a report from the Children''s Oncology Group Study POG 9421.
- Acute leukemia in children with Down syndrome.
Schools
Schulich School Of Medicine At The University Of Western Ontario
Victoria Hospital
Chldns Hospital Of Mich
Conditions Treated
- Acute Leukemia
- Anemia
- Hodgkin's Disease
- Leukocytosis
- View All
Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
Awards
- Regional Top Doctor
- Fellow (FAAP)
- Super Doctor
Education
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University of Western Ontario
Hospital
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DMC - Children's Hospital of Michigan
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