Physician
Plastic Surgery
Dr. Jeffrey Isenberg, MD
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Jeffrey Isenberg, MD is an expert in the field of Plastic Surgery. Jeffrey Isenberg is a published doctor. He published 101 publications, including: 'The calcaneal subtendinous space for passage of the pedicle in free-flap reconstruction of lateral ankle defects.'
Publications
- HIF-2α-Mediated Induction of Pulmonary Thrombospondin-1 Contributes to Hypoxia-Driven Vascular Remodeling and Vasoconstriction.
- Thrombospondin-1 Activation of Signal-Regulatory Protein-α Stimulates Reactive Oxygen Species Production and Promotes Renal Ischemia Reperfusion Injury.
- Time Spent Before the Mast: An Emerging Role for Mast Cells in Prosthetic Breast Implant Capsule Formation.
- Thrombospondin-1 and CD47 signaling regulate healing of thermal injury in mice.
- Protein-tyrosine Phosphatase 4A3 (PTP4A3) Promotes Vascular Endothelial Growth Factor Signaling and Enables Endothelial Cell Motility.
- Nerve regeneration and elastin formation within poly(glycerol sebacate)-based synthetic arterial grafts one-year post-implantation in a rat model.
- Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe pulmonary arterial hypertension.
- Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47.
- Age-Associated Induction of Cell Membrane CD47 Limits Basal and Temperature-Induced Changes in Cutaneous Blood Flow.
- Activated CD47 Promotes Pulmonary Arterial Hypertension Through Targeting Caveolin-1.
- Thrombospondin-1/CD47 blockade following ischemia-reperfusion injury is tissue protective.
- Molecular mechanisms for discrete nitric oxide levels in cancer.
- The chemical biology of nitric oxide: implications in cellular signaling.
- Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways.
- Upper lip reconstruction with the alar crescent flap: A new approach.
- The activation of metabolites of nitric oxide synthase by metals is both redox and oxygen dependent: a new feature of nitrogen oxide signaling.
- The biphasic nature of nitric oxide responses in tumor biology.
- Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1.
- Hematopoietic stem cells mobilization and immune response in tumor-bearing mice.
- Sense and sensibility: breast reconstruction with innervated TRAM flaps.
- Thrombospondin-1 and CD47 regulate blood pressure and cardiac responses to vasoactive stress.
- Type I collagen is a molecular target for inhibition of angiogenesis by endogenous thrombospondin-1.
- CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1.
- Regulation of nitric oxide signalling by thrombospondin 1: implications for anti-angiogenic therapies.
- Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.
- Thrombospondin-1 supports blood pressure by limiting eNOS activation and endothelial-dependent vasorelaxation.
- Thrombospondin-1 inhibits VEGF receptor-2 signaling by disrupting its association with CD47.
- Thrombospondin-1 inhibition of vascular smooth muscle cell responses occurs via modulation of both cAMP and cGMP.
- Nitric oxide modulation of low-density mononuclear cell transendothelial migration.
- Modulation of angiogenesis by dithiolethione-modified NSAIDs and valproic acid.
- Additional follow-up with microvascular transfer in the treatment of chronic venous stasis ulcers.
- Nitric oxide modulation of early angiogenesis.
- CD47: a new target in cardiovascular therapy.
- Age-dependent regulation of skeletal muscle mitochondria by the thrombospondin-1 receptor CD47.
- When less is more: revascularization and sural artery fasciocutaneous flaps in ischemic limb salvage.
- Quantitative evaluation of the effects of gravity and dependency on microvascular tissue transfer to the lower limb, with clinical applications.
- The reversal sural artery neurocutaneous island flap in composite lower extremity wound reconstruction.
- Permanent lip augmentation using autologous breast implant capsule.
- Nitric oxide in wound-healing.
- Thiolutin inhibits endothelial cell adhesion by perturbing Hsp27 interactions with components of the actin and intermediate filament cytoskeleton.
- Nasopalatine duct cysts and the role of magnetic resonance imaging.
- Salvage and reconstruction of complex post-extirpative knee wounds: a successful surgical protocol.
- Immediate tendon Achilles reconstruction with composite palmaris longus grafts.
- The limited value of preoperative angiography in microsurgical reconstruction of the lower limb.
- Timing, magnitude, and utility of surgical delay in the TRAM flap: I. Animal studies.
- Rectus abdominis muscle transplant in lower limb salvage: a recent series of 25 patients.
- Subtotal calcanectomy for osteomyelitis of the os calcis: a reasonable alternative to free tissue transfer.
- Computer-generated slide graphics on a shoestring budget.
- Microvascular transfers in the treatment of massive long-bone osteomyelitis: filling the dugout canoe.
- Aesthetic concerns in pectoralis major muscle flap harvesting for head and neck reconstruction.
- The natural history of pressure sores in a community hospital environment.
- Further clinical experience in permanent lip augmentation using autologous breast implant capsule.
- Regulation of soluble guanylate cyclase by matricellular thrombospondins: implications for blood flow.
- Reverse neurocutaneous radial artery island flap salvage of a rodeo thumb degloving injury in a nine-year-old.
- Inhibition of nitric oxide synthase (NOS) conversion of L-arginine to nitric oxide (NO) decreases low density mononuclear cell (LD MNC) trans-endothelial migration and...
- It is never too late: limb salvage following a half-century of long-bone osteomyelitis.
- Flying solo: a single year-single surgeon community hospital replantation/ revascularization experience.
- Necrotizing fasciitis of the periorbita and forehead.
- Additional experience with hemi-metatarsal vascularized bone transfer for treatment of phalangeal osteomyelitis.
- The calcaneal subtendinous space for passage of the pedicle in free-flap reconstruction of lateral ankle defects.
- Zone of injury: a valid concept in microvascular reconstruction of the traumatized lower limb?
- Microvascular transplantation in the salvage of lower extremity trauma in the elderly.
- Rodeo thumb: an unusual etiology of avulsion amputation of the thumb.
- Mammary gangrene associated with warfarin ingestion.
- What you see is what you get: lack of significant postoperative contour change in muscle transplants to the lower leg.
- The great saphenous vein fasciocutaneous island flap for immediate calcaneal wound reconstruction.
- Comprehensive characterization of heat shock protein 27 phosphorylation in human endothelial cells stimulated by the microbial dithiole thiolutin.
- Re: Selective use of preoperative lower extremity arteriography and free flap reconstruction.
- Surgical research and the ethics of being first.
- Occasions for multiple flaps in lower-limb reconstructions: once is sometimes not enough.
- Early free-flap debulking: avoiding the second donor site.
- Acceptability of sternal scars in reduction of massively enlarged breasts.
- Trapezius island myocutaneous flap.
- Bilateral simultaneous groin flaps in the salvage of a pediatric blast-injured hand.
- Multiple recurrent benign schwannomas of deep and superficial nerves of the upper extremity: a new variant of segmental neurofibromatosis.
- Re: Vascularized fascial patch for repair of suboccipital dural defect.
- Cutaneous pulse oximetry in the preoperative assessment of devascularized digits.
- Spontaneous exercise-induced thrombosis of the radial artery: a case report and literature review.
- The legacy of Narcissus.
- Role of the mitochondrial membrane permeability transition (MPT) in rotenone-induced apoptosis in liver cells.
- Oxidative stress in nongenotoxic carcinogenesis.
- Comparative in vivo hepatic effects of Di-isononyl phthalate (DINP) and related C7-C11 dialkyl phthalates on gap junctional intercellular communication (GJIC), peroxis...
- Effects of Di-2-ethylhexyl phthalate (DEHP) on gap-junctional intercellular communication (GJIC), DNA synthesis, and peroxisomal beta oxidation (PBOX) in rat, mouse, a...
- Reversibility and persistence of di-2-ethylhexyl phthalate (DEHP)- and phenobarbital-induced hepatocellular changes in rodents.
- Cardiac CD47 Drives Left Ventricular Heart Failure Through Ca2+-CaMKII-Regulated Induction of HDAC3.
- Thrombospondin-1-CD47 blockade and exogenous nitrite enhance ischemic tissue survival, blood flow and angiogenesis via coupled NO-cGMP pathway activation.
- Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner.
- Guanylyl cyclase-dependent chemotaxis of endothelial cells in response to nitric oxide gradients.
- Further experience with innervated autologous flaps in postoncologic breast reconstruction.
- Endogenous thrombospondin-1 is not necessary for proliferation but is permissive for vascular smooth muscle cell responses to platelet-derived growth factor.
- Thrombospondin-1 antagonizes nitric oxide-stimulated vascular smooth muscle cell responses.
- Thrombospondin-1 limits ischemic tissue survival by inhibiting nitric oxide-mediated vascular smooth muscle relaxation.
- Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake.
- Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling.
- Blocking thrombospondin-1/CD47 signaling alleviates deleterious effects of aging on tissue responses to ischemia.
- Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts.
- Gene silencing of CD47 and antibody ligation of thrombospondin-1 enhance ischemic tissue survival in a porcine model: implications for human disease.
- Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling.
- Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.
- Enhancing cardiovascular dynamics by inhibition of thrombospondin-1/CD47 signaling.
Doctors Specialties
- Orthopedic Hand Surgery
- Plastic Surgery
Accepted Insurances
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