Physician
Infectious Disease
Dr. Jeffrey D. Chulay, MD
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Jeffrey Chulay is an expert in the field of Infectious Disease. He graduated from Northwestern University Feinberg School of Medicine. Northwestern University Feinberg School of Medicine is ranked 19/29 in Research/PrimaryCare. Jeffrey Chulay is a published MD. He has 101 papers published. The most current publication "Splenic abscess. Report of 10 cases and review of the literature."
Publications
- Safety and Biodistribution Evaluation in Cynomolgus Macaques of rAAV2tYF-PR1.7-hCNGB3, a Recombinant AAV Vector for Treatment of Achromatopsia.
- Herpes Simplex Virus Clearance During Purification of a Recombinant Adeno-Associated Virus Serotype 1 Vector.
- Development, validation and use of ELISA for antibodies to human alpha-1 antitrypsin.
- Phase 2 Clinical Trial of a Recombinant Adeno-associated Virus Vector Expressing Alpha 1 Antitrypsin: Interim Results.
- Preclinical evaluation of a recombinant adeno-associated virus vector expressing human alpha-1 antitrypsin made using a recombinant herpes simplex virus production met...
- Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy.
- Cellular and humoral immune responses to alphavirus replicon vaccines expressing cytomegalovirus pp65, IE1, and gB proteins.
- Preconceptual administration of an alphavirus replicon UL83 (pp65 homolog) vaccine induces humoral and cellular immunity and improves pregnancy outcome in the guinea p...
- Atovaquone/proguanil therapy for Plasmodium falciparum and Plasmodium vivax malaria in Indonesians who lack clinical immunity.
- Development and preclinical evaluation of an alphavirus replicon vaccine for influenza.
- Development and preclinical evaluation of an alphavirus replicon particle vaccine for cytomegalovirus.
- Randomized, double-blind, Phase 1 trial of an alphavirus replicon vaccine for cytomegalovirus in CMV seronegative adult volunteers.
- Randomized, placebo-controlled trial of atovaquone/proguanil for the prevention of Plasmodium falciparum or Plasmodium vivax malaria among migrants to Papua, Indonesia.
- Disseminated histoplasmosis in a Kenyan African child: a case report.
- Validation of an enzyme immunoassay for serodiagnosis of acute Q fever.
- Passive immunization of Aotus monkeys with human antibodies to the Plasmodium falciparum antigen Pf155/RESA.
- Development of novel benzimidazole riboside compounds for treatment of cytomegalovirus disease.
- Causal prophylactic efficacy of atovaquone-proguanil (Malarone) in a human challenge model.
- Atovaquone-proguanil versus mefloquine for malaria prophylaxis in nonimmune travelers: results from a randomized, double-blind study.
- Atovaquone plus proguanil versus halofantrine for the treatment of imported acute uncomplicated Plasmodium falciparum malaria in non-immune adults: a randomized compar...
- Atovaquone-proguanil versus chloroquine-proguanil for malaria prophylaxis in non-immune travellers: a randomised, double-blind study. Malarone International Study Team.
- Atovaquone and proguanil hydrochloride followed by primaquine for treatment of Plasmodium vivax malaria in Thailand.
- Malarone (atovaquone and proguanil hydrochloride): a review of its clinical development for treatment of malaria. Malarone Clinical Trials Study Group.
- Challenges in the development of antimalarial drugs with causal prophylactic activity.
- Merozoite surface protein-1 epitopes recognized by antibodies that inhibit Plasmodium falciparum merozoite dispersal.
- Manifestations resembling thrombotic microangiopathy in patients with advanced human immunodeficiency virus (HIV) disease in a cytomegalovirus prophylaxis trial (ACTG ...
- Clinical manifestations of Plasmodium falciparum malaria experimentally induced by mosquito challenge.
- Immunization of owl monkeys with a recombinant protein containing repeated epitopes of a Plasmodium falciparum glycophorin-binding protein.
- Molecular basis of sequestration in severe and uncomplicated Plasmodium falciparum malaria: differential adhesion of infected erythrocytes to CD36 and ICAM-1.
- Host receptors for malaria-infected erythrocytes.
- Safety and immunogenicity of a Plasmodium vivax sporozoite vaccine.
- Use of adjuvant containing mycobacterial cell-wall skeleton, monophosphoryl lipid A, and squalane in malaria circumsporozoite protein vaccine.
- Plasmodium falciparum: chymotryptic-like proteolysis associated with a 101-kDa acidic-basic repeat antigen.
- Serum concentrations of penicillin, doxycycline, and ciprofloxacin during prolonged therapy in rhesus monkeys.
- Septic arthritis in an infant due to Clostridium ghoni and Hemophilus parainfluenzae.
- Splenic abscess. Report of 10 cases and review of the literature.
- Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique.
- Cultured Plasmodium falciparum used as antigen in a malaria indirect fluorescent antibody test.
- Leishmaniasis: a case history and treatment failure with rifampin.
- Determination of chloroquine and its de-ethylated metabolites in human plasma by ion-pair high-performance liquid chromatography.
- Susceptibility of clinically sensitive and resistant Leishmania to pentavalent antimony in vitro.
- Inhibition of in vitro growth of Plasmodium falciparum by immune serum from monkeys.
- Inhibitory effects of immune monkey serum on synchronized Plasmodium falciparum cultures.
- Quantitation of amastigotes of Leishmania donovani in smears of splenic aspirates from patients with visceral leishmaniasis.
- Comparison of microscopy and culture in the detection of Leishmania donovani from splenic aspirates.
- Comparison of three culture media for isolating Leishmania donovani from splenic aspirates in Kenyan visceral leishmaniasis.
- Separation and identification of a plasma and urinary mono-acetylated conjugate of chloroquine in man by ion-pair high-performance liquid chromatography.
- A new in vitro test for pyrimethamine/sulfadoxine susceptibility of Plasmodium falciparum and its correlation with in vivo resistance in Kenya.
- The activity of proguanil and its metabolites, cycloguanil and p-chlorophenylbiguanide, against Plasmodium falciparum in vitro.
- In vitro antimalarial activity of tetrahydrofolate dehydrogenase inhibitors.
- Synergistic antimalarial activity of pyrimethamine and sulfadoxine against Plasmodium falciparum in vitro.
- Plasmodium falciparum in Kisumu, Kenya: differences in sensitivity to amodiaquine and chloroquine in vitro.
- Field evaluation in Kenya of a 48-hour in vitro test for Plasmodium falciparum sensitivity to chloroquine.
- Chloroquine-resistant falciparum malaria.
- Plasmodium falciparum: assessment of in vitro growth by [3H]hypoxanthine incorporation.
- High-dose sodium stibogluconate treatment of cutaneous leishmaniasis in Kenya.
- A comparison of three dosage regimens of sodium stibogluconate in the treatment of visceral leishmaniasis in Kenya.
- Changing in vitro response to chloroquine of Plasmodium falciparum in Kenya.
- Treatment of visceral leishmaniasis using sodium stibogluconate in a dose of 15 mg antimony/kg body weight twice daily for 30 days: a preliminary report.
- Complications of kala azar and its treatment in Kenya.
- Leishmania donovani parasitaemia in Kenyan visceral leishmaniasis.
- Selective stage-specific changes in the permeability to small hydrophilic solutes of human erythrocytes infected with Plasmodium falciparum.
- Serotypes of Plasmodium falciparum defined by immune serum inhibition of in vitro growth.
- In vitro response of Kenyan Plasmodium falciparum to chloroquine in different media.
- Antagonism of sulfadoxine and pyrimethamine antimalarial activity in vitro by p-aminobenzoic acid, p-aminobenzoylglutamic acid and folic acid.
- Chloroquine metabolism in man: urinary excretion of 7-chloro-4-hydroxyquinoline and 7-chloro-4-aminoquinoline metabolites.
- The suitability of East African primates as animal models of visceral leishmaniasis.
- Plasmodium falciparum antigens synthesized by schizonts and stabilized at the merozoite surface by antibodies when schizonts mature in the presence of growth inhibitor...
- Malaria transmitted to humans by mosquitoes infected from cultured Plasmodium falciparum.
- Monoclonal antibody characterization of Plasmodium falciparum antigens in immune complexes formed when schizonts rupture in the presence of immune serum.
- Naturally acquired antibodies to sporozoites do not prevent malaria: vaccine development implications.
- Invasion of mouse erythrocytes by the human malaria parasite, Plasmodium falciparum.
- American cutaneous leishmaniasis: presentation and problems of patient management.
- Bacteremic Citrobacter freundii cellulitis associated with tub immersion in a patient with the nephrotic syndrome.
- Vaccines for human malaria: epidemiological and immunological perspectives.
- Primary structure of a Plasmodium falciparum malaria antigen located at the merozoite surface and within the parasitophorous vacuole.
- Visceral leishmaniasis unresponsive to antimonial drugs. III. Successful treatment using a combination of sodium stibogluconate plus allopurinol.
- Visceral leishmaniasis unresponsive to antimonial drugs. II. Response to high dosage sodium stibogluconate or prolonged treatment with pentamidine.
- Visceral leishmaniasis unresponsive to antimonial drugs. I. Clinical and immunological studies.
- Electron microscopy of Leishmania donovani in splenic aspirates from patients with visceral leishmaniasis during treatment with sodium stibogluconate.
- American cutaneous leishmaniasis: a comparison of three sodium stibogluconate treatment schedules.
- Electrocardiographic changes during treatment of leishmaniasis with pentavalent antimony (sodium stibogluconate).
- Safety and efficacy of high-dose sodium stibogluconate therapy of American cutaneous leishmaniasis.
- A preliminary pharmacokinetic study of the antimalarial drugs, proguanil and chlorproguanil.
- Pharmacokinetics of antimony during treatment of visceral leishmaniasis with sodium stibogluconate or meglumine antimoniate.
- Development of sporozoite vaccines for malaria.
- Immunogenicity of liposomal malaria sporozoite antigen in monkeys: adjuvant effects of aluminium hydroxide and non-pyrogenic liposomal lipid A.
- Long-term cultured human vascular endothelial cells (EC-FP5) bind Plasmodium falciparum infected erythrocytes.
- Development of asexual erythrocytic malaria vaccines.
- Immunization of Saimiri sciureus boliviensis with recombinant vaccines based on the circumsporozoite protein of Plasmodium vivax.
- Comparison of thick films, in vitro culture and DNA hybridization probes for detecting Plasmodium falciparum malaria.
- Specificities of antibodies that inhibit merozoite dispersal from malaria-infected erythrocytes.
- Activation of monocytes and platelets by monoclonal antibodies or malaria-infected erythrocytes binding to the CD36 surface receptor in vitro.
- Identification of a platelet membrane glycoprotein as a falciparum malaria sequestration receptor.
- Human lymphocyte proliferative response to a sporozoite T cell epitope correlates with resistance to falciparum malaria.
- Rapid diagnosis of malaria by acridine orange staining of centrifuged parasites.
- Plasmodium falciparum sequestration: OKM5 antigen (CD36) mediates cytoadherence of parasitized erythrocytes to a myelomonocytic cell line.
- Monoclonal antibody characterization of the 195-kilodalton major surface glycoprotein of Plasmodium falciparum malaria schizonts and merozoites: identification of addi...
- Epitope map and processing scheme for the 195,000-dalton surface glycoprotein of Plasmodium falciparum merozoites deduced from cloned overlapping segments of the gene.
- Safety and Biodistribution Evaluation in CNGB3-Deficient Mice of rAAV2tYF-PR1.7-hCNGB3, a Recombinant AAV Vector for Treatment of Achromatopsia.
Schools
Northwestern Center Feinberg School of Medicine
Cleveland Metropolitan General Hospital
Walter Reed Army Med Center
Doctors Specialties
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
Education
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Case Western Reserve University - MetroHealth -
Northwestern University Feinberg School of Medicine
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