Professor of Pediatrics, University Cincinnati
Neonat/Perinatology
Dr. Jeffrey A. Whitsett, MD
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Dr. Jeffrey A. Whitsett works in the field of Neonat/Perinatology. He researched medicine at Columbia University College of Physicians & Surgeons. Columbia University College of Physicians & Surgeons is a one of the best medicals schools. Columbia University College of Physicians & Surgeons is ranked 8 in research and 52 in primary care medicine He received 2 awards: "America's Top Doctors" and "Elected Member". Jeffrey Whitsett has written publications. He has 101 publications published with PubMed. The lastest paper is: 'INFLAMMATION. Modulating pulmonary inflammation.'
Publications
- INFLAMMATION. Modulating pulmonary inflammation.
- 'LungGENS': a web-based tool for mapping single-cell gene expression in the developing lung.
- Mesenchymal Wnt signaling promotes formation of sternum and thoracic body wall.
- Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung.
- TGFβ signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium.
- Respiratory epithelial cells orchestrate pulmonary innate immunity.
- Differential roles of STAT3 in the initiation and growth of lung cancer.
- SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene.
- Diffuse lung disease in children: Summary of a scientific conference.
- Sox17 is required for normal pulmonary vascular morphogenesis.
- Foxa3 Induces Goblet Cell Metaplasia and Inhibits Innate Antiviral Immunity.
- Uterine deletion of gp130 or stat3 shows implantation failure with increased estrogenic responses.
- Spdef Null Mice Lack Conjunctival Goblet Cells and Provide a Model of Dry Eye.
- Molecular determinants of lung development.
- Orphan G Protein-Coupled Receptor GPR116 Regulates Pulmonary Surfactant Pool Size.
- Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated ?1/?2-integrin trafficking.
- Wntless is required for peripheral lung differentiation and pulmonary vascular development.
- FOXM1 promotes allergen-induced goblet cell metaplasia and pulmonary inflammation.
- Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition.
- Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium.
- Kruppel-like factor 5 (KLF5) is critical for conferring uterine receptivity to implantation.
- Rapamycin Decreases Airway Remodeling and Hyperreactivity in a Transgenic Model of Noninflammatory Lung Disease.
- GM-CSF modulates pulmonary resistance to influenza A infection.
- Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium.
- Integrin ?6?4 defines a novel lung epithelial progenitor cell: a step forward for cell-based therapies for pulmonary disease.
- Notch and Basal Cells Take Center Stage during Airway Epithelial Regeneration.
- Intersections Between Pulmonary Development and Disease.
- Cell Plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010.
- Airway Epithelial Transcription Factor NKX2-1 Inhibits Mucous Cell Metaplasia and Th2 Inflammation.
- Ectopic activation of epithelial differentiation pathways in idiopathic pulmonary fibrosis.
- GM-CSF in the lung protects against lethal influenza infection.
- Ectopic respiratory epithelial cell differentiation in bronchiolised distal airspaces in idiopathic pulmonary fibrosis.
- Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma.
- Conditional depletion of airway progenitor cells induces peribronchiolar fibrosis.
- Maternal synchronization of gestational length and lung maturation.
- A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma.
- Interference with intraepithelial TNF-α signaling inhibits CD8(+) T-cell-mediated lung injury in influenza infection.
- Hereditary pulmonary alveolar proteinosis: pathogenesis, presentation, diagnosis, and therapy.
- Increased expression of FoxM1 transcription factor in respiratory epithelium inhibits lung sacculation and causes Clara cell hyperplasia.
- Sox2 Activates Cell Proliferation and Differentiation in the Respiratory Epithelium.
- Kruppel-like factor 5 is not required for K-RasG12D lung tumorigenesis, but represses ABCG2 expression and is associated with better disease-specific survival.
- Pulmonary pathology in thyroid transcription factor-1 deficiency syndrome.
- Signaling pathways in the epithelial origins of pulmonary fibrosis.
- Fatal familial lung disease caused by ABCA3 deficiency without identified ABCA3 mutations.
- Patient-derived granulocyte/macrophage colony-stimulating factor autoantibodies reproduce pulmonary alveolar proteinosis in nonhuman primates.
- Foxa2 programs Th2 cell-mediated innate immunity in the developing lung.
- Surfactant protein-d inhibits lung inflammation caused by ventilation in premature newborn lambs.
- The pulmonary collectins and respiratory syncytial virus: is there a clinical link?
- Conditional Deletion of Abca3 in Alveolar Type II Cells Alters Surfactant Homeostasis in Newborn and Adult Mice.
- Inhibition of PI3K by PX-866 prevents transforming growth factor-alpha-induced pulmonary fibrosis.
- Review: The intersection of surfactant homeostasis and innate host defense of the lung: lessons from newborn infants.
- Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease.
- Human GM-CSF autoantibodies and reproduction of pulmonary alveolar proteinosis.
- Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis.
- SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production.
- Early growth response-1 suppresses epidermal growth factor receptor-mediated airway hyperresponsiveness and lung remodeling in mice.
- Pulmonary surfactant surface tension influences alveolar capillary shape and oxygenation.
- Developmental aspects of the upper airway: report from an NHLBI Workshop, March 5-6, 2009.
- Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development.
- C/EBP{alpha} is required for pulmonary cytoprotection during hyperoxia.
- Genetic disorders of surfactant dysfunction.
- Sox17 regulates organ lineage segregation of ventral foregut progenitor cells.
- Surfactant protein-D regulates the postnatal maturation of pulmonary surfactant lipid pool sizes.
- Deletion of Scap in alveolar type II cells influences lung lipid homeostasis and identifies a compensatory role for pulmonary lipofibroblasts.
- Conditional expression of genes in the respiratory epithelium in transgenic mice: cautionary notes and toward building a better mouse trap.
- Deletion of Forkhead Box M1 transcription factor from respiratory epithelial cells inhibits pulmonary tumorigenesis.
- Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells.
- Sox17 promotes cell cycle progression and inhibits TGF-beta/Smad3 signaling to initiate progenitor cell behavior in the respiratory epithelium.
- Forkhead Box m1 transcription factor is required for perinatal lung function.
- Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA.
- Pulmonary mastocytosis and enhanced lung inflammation in mice heterozygous null for the Foxf1 gene.
- Resident cellular components of the lung: developmental aspects.
- Amniotic fluid concentration of surfactant proteins in intra-amniotic infection.
- The concentration of surfactant protein-A in amniotic fluid decreases in spontaneous human parturition at term.
- A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration.
- Macrophage dysfunction and susceptibility to pulmonary Pseudomonas aeruginosa infection in surfactant protein C-deficient mice.
- CUL2 is required for the activity of hypoxia-inducible factor and vasculogenesis.
- Alveolar epithelial STAT3, IL-6 family cytokines, and host defense during Escherichia coli pneumonia.
- STAT-3 regulates surfactant phospholipid homeostasis in normal lung and during endotoxin-mediated lung injury.
- EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis.
- GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium.
- Surfactant protein D alters allergic lung responses in mice and human subjects.
- STAT3 regulates ABCA3 expression and influences lamellar body formation in alveolar type II cells.
- Conditional deletion of Pten causes bronchiolar hyperplasia.
- Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation.
- Down the primrose path: petechiae in a neonate exposed to herbal remedy for parturition.
- Combined Inactivation of MYC and K-Ras oncogenes reverses tumorigenesis in lung adenocarcinomas and lymphomas.
- Sterol response element binding protein and thyroid transcription factor-1 (Nkx2.1) regulate Abca3 gene expression.
- Surfactant protein-D and surfactant inhibit endotoxin-induced pulmonary inflammation.
- Duration-dependent cytoprotective versus inflammatory effects of lung epithelial fibroblast growth factor-7 expression.
- Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice.
- Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis.
- Epithelial-vascular cross talk mediated by VEGF-A and HGF signaling directs primary septae formation during distal lung morphogenesis.
- SPDEF regulates goblet cell hyperplasia in the airway epithelium.
- Surfactant protein D regulates the cell surface expression of alveolar macrophage beta(2)-integrins.
- Transcriptional control of lung morphogenesis.
- IL-1beta disrupts postnatal lung morphogenesis in the mouse.
- GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS.
- Expression of ABCA3 in developing lung and other tissues.
- Persistent tachypnea and hypoxia in a 3-month-old term infant.
Schools
Columbia University College of Physicians And Surgeons
Doctors Specialties
- Neonatal Medicine
- Neonat/Perinatology
Accepted Insurances
Awards
- America's Top Doctors
- Elected Member
Education
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Cincinnati Children's Hospital Medical Center -
Mount Sinai School of Medicine -
Columbia University College of Physicians & Surgeons
Hospital
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Cincinnati Children's Hospital Medical Center
Drug Facts
| NPI NUMBER | 1528142825 | |
| NPPES Provider LastName | WHITSETT | |
| NPPES Provider FirstName | JEFFREY | |
| NPPES Provider ZIPCode | 770556453 | |
| NPPES Provider State | TX | |
| Specialty Description | Ophthalmology | |
| Total Claim Count | 1306.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1528142825 |
| Last Name Of The Provider | WHITSETT |
| First Name Of The Provider | JEFFREY |
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