Professor, Internal Medicine, UCSF School of Medicine
Cardiology
Dr. Jay A. Nadel, MD
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Nadel practices Cardiology. He graduated from Jefferson Medical College. He has 1 awards "Elected Member". Jay A. Nadel is a published doctor and has 100 publications published. The lastest was: 'Proteolytic enzymes and airway diseases.' Nadel accepts Medicare payments and is listed with Medicare.gov.
Publications
- Understanding the pathophysiology of the Asthma-chronic obstructive pulmonary disease overlap syndrome.
- EGFR activation suppresses Respiratory virus-induced IRF1-dependent CXCL10 production.
- Unsuspected mild emphysema in nonsmoking patients with chronic Asthma with persistent airway obstruction.
- The CFTR and EGFR relationship in airway vascular growth, and its importance in Cystic fibrosis.
- Respiratory virus-induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium.
- Mucous hypersecretion and relationship to cough.
- Arachidonate 15-lipoxygenase from human leukocytes: purification and structural homology to other mammalian lipoxygenases.
- Effects of mast cell-derived mediators on epithelial cells in canine trachea.
- Ion transport across cat and ferret tracheal epithelia.
- Cold air-induced bronchoconstriction is mediated by tachykinin and kinin release in guinea pigs.
- Tachykinins mediate the potentiation of antigen-induced bronchoconstriction by cold air in guinea pigs.
- Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro.
- PACAP 1-38 as an inhaled bronchodilator in guinea pigs in vivo.
- Inhibition of bronchoconstriction by pituitary adenylate cyclase activating polypeptide (PACAP 1-27) in guinea-pigs in vivo.
- Arachidonate 15-lipoxygenase (omega-6 lipoxygenase) from human leukocytes. Purification and structural homology to other mammalian lipoxygenases.
- Globule leukocytes and mast cells in the rat trachea: their number, distribution, and response to compound 48/80 and dexamethasone.
- Dog mastocytoma tryptase: affinity purification, characterization, and amino-terminal sequence.
- Modulation of tachykinins and bradykinin by enkephalinase.
- Molecular cloning and Primary structure of human 15-lipoxygenase.
- Modulation of cholinergic neurotransmission by vasoactive intestinal peptide in ferret trachea.
- Cholinergic neuromodulation by prostaglandin D2 in canine airway smooth muscle.
- Histochemical comparison of mast cells obtained from the airways of mongrel dogs and Basenji-Greyhound dogs by bronchoalveolar lavage.
- Neutral endopeptidase inhibitors potentiate substance P-induced contraction in gut smooth muscle.
- Recombinant human enkephalinase (neutral endopeptidase) prevents cough induced by tachykinins in awake guinea pigs.
- Neutral endopeptidase inhibitors potentiate substance P- and capsaicin-induced cough in awake guinea pigs.
- Neurogenic inflammation in airways and its modulation by peptidases.
- Neutral endopeptidase modulates endothelin-1-induced airway smooth muscle contraction in guinea-pig trachea.
- Distribution of chymase-containing mast cells in human bronchi.
- Neutral endopeptidase and kininase II mediate glucocorticoid inhibition of neurogenic inflammation in the rat trachea.
- Role of nitric oxide and septide-insensitive NK(1) receptors in bronchoconstriction induced by aerosolised neurokinin A in guinea-pigs.
- Enkephalinase inhibitor potentiates substance P- and electrically induced contraction in ferret trachea.
- Cloning and expression of human arachidonate 15-lipoxygenase.
- Mast cell tryptase causes airway smooth muscle hyperresponsiveness in dogs.
- Arachidonate 15-lipoxygenase from human eosinophil-enriched leukocytes: partial purification and properties.
- Inhibition of neutral endopeptidase potentiates neurogenic inflammation in the rat trachea.
- Aspects of coronary vasomotor regulation.
- Object retrieval through observational learning in 8- to 18-month-old infants.
- Neurogenic vasodilation in the rat nasal mucosa involves neurokinin1 tachykinin receptors.
- A new NK1 receptor antagonist (CP-99,994) prevents the increase in tracheal vascular permeability produced by hypertonic saline.
- Role of kinins in anaphylactic-induced bronchoconstriction mediated by tachykinins in guinea-pigs.
- Tryptase and chymase: comparison of extraction and release in two dog mastocytoma lines.
- Tachykinins and kinins in antigen-evoked plasma extravasation in guinea-pig nasal mucosa.
- Enkephalinase inhibitor potentiates mammalian tachykinin-induced contraction in ferret trachea.
- Substance P and vasoactive intestinal peptide degradation by mast cell tryptase and chymase.
- Substance P-induced increase in vascular permeability in the rat trachea does not depend on neutrophils or other components of circulating blood.
- Secreted mucosal mediators in airway epithelium.
- Toluene diisocyanate contracts guinea pig bronchial smooth muscle by activating capsaicin-sensitive sensory nerves.
- Catabolism of calcitonin gene-related peptide and substance P by neutral endopeptidase.
- Biologic effects of mast cell enzymes.
- Giles F. Filley Lecture. Epithelial cells as modulators. Possible role of 15-lipoxygenase in allergic Diseases.
- Autoradiographic studies of the distribution of 35sulfate label in ferret trachea: effects of stimulation.
- Nonmuscular airway obstruction and Asthma.
- Endogenous nitric oxide inhibits bronchoconstriction induced by cold-air inhalation in guinea pigs: role of kinins.
- Acute effects of inhalation of cigarette smoke on airway conductance.
- Parainfluenza virus Infection of cultured airway epithelial cells.
- Effect of gamma-aminobutyric acid on neurally mediated contraction of guinea pig trachealis smooth muscle.
- Bronchial hyperresponsiveness in normal subjects during attenuated influenza virus Infection.
- Clearing the air: the links between occupational and environmental air pollution control.
- The roentgenologic manifestations of emphysema and Chronic bronchitis.
- Human Respiratory mucus.
- Powdered tantalum: its use as a roentgenographic contrast material.
- Inflammation and Asthma.
- Bradykinin increases intracellular calcium levels in a human bronchial epithelial cell line via the B2 receptor subtype.
- Proteolytic enzymes and airway Diseases.
- Chronic obstructive pulmonary disease with intermediate alpha-1-antitrypsin deficiency.
- Physiologic diagnosis of subclinical Emphysema.
- Mechanisms limiting airflow in bullous lung Disease.
- Indomethacin inhibits the airway hyperresponsiveness but not the neutrophil influx induced by ozone in dogs.
- Regulation of Na+ and Cl- transport and mucous gland secretion in airway epithelium.
- [Effect of lesions of the airway epithelium on hyperirritability of the Respiratory tract].
- Neutrophil depletion inhibits airway hyperresponsiveness induced by ozone exposure.
- An anti-inflammatory drug (BW755C) inhibits airway hyperresponsiveness induced by ozone in dogs.
- Inhibition of antigen-induced airway hyperresponsiveness by a thromboxane synthetase inhibitor (OKY-046) in allergic dogs.
- Aerosol effects on smooth muscle and airway visualization technique.
- Neural control of airway submucosal gland secretion.
- Control of mucus secretion and ion transport in airways.
- Alternative mechanisms for tiotropium.
- Tachykinins mediate contraction of the human lower esophageal sphincter in vitro via activation of NK2 receptors.
- Importance of airway inflammation for hyperresponsiveness induced by ozone.
- Characterization of beta adrenoceptor subtypes in canine airway smooth muscle by radioligand binding and physiological responses.
- IL-13-induced Clara cell secretory protein expression in airway epithelium: role of EGFR signaling pathway.
- Neutrophil elastase induces mucin production by ligand-dependent epidermal growth factor receptor activation.
- Tumor necrosis factor alpha-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells.
- Metalloproteinases mediate mucin 5AC expression by epidermal growth factor receptor activation.
- Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells.
- E-cadherin promotes EGFR-mediated cell differentiation and MUC5AC mucin expression in cultured human airway epithelial cells.
- Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-alpha-c...
- A morphometric study of mucins and small airway plugging in Cystic fibrosis.
- Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade.
- MUC5AC, a gel-forming mucin accumulating in gallstone Disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder.
- Innate immune mucin production via epithelial cell surface signaling: relationship to allergic Disease.
- Regulation of interleukin-8 via an airway epithelial signaling cascade.
- Acrolein-activated matrix metalloproteinase 9 contributes to persistent mucin production.
- Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium.
- fMLP causes degranulation followed by regranulation in rat nasal glands.
- Cigarette smoke induces MUC5AC mucin overproduction via tumor necrosis factor-alpha-converting enzyme in human airway epithelial (NCI-H292) cells.
- Role of neutrophils in mucus hypersecretion in COPD and implications for therapy.
- Lipopolysaccharide initiates a positive feedback of epidermal growth factor receptor signaling by prostaglandin E2 in human biliary carcinoma cells.
- Fibrinogen binding to ICAM-1 promotes EGFR-dependent mucin production in human airway epithelial cells.
Schools
Thomas Jefferson University
Conditions Treated
- Asthma
- Bronchiectasis
- COPD (Chronic Obstructive Pulmonary Disease)
- Cystic Fibrosis
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Doctors Specialties
- Pulmonology
- Cardiology
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Vitalidad Plus California Con Aetna
- Blue Card PPO
- Advantage Preferred DirectAccess Plus PPO
- Blue Cross Blue Shield of California PPO
- Pathway X Direct Access PPO
- Pathway X Tiered Direct Access
- Select PPO
- Brown & Toland Physicians
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- LocalPlus
- Open Access Plus
- Commercial Insurance Company
- Delta Health System
- First Health (Coventry Health Care) PPO
- Covered California - Bronze PPO
- Health Net PPO
- Individual and Family PPO
- Medicare Advantage PFFS
- Medicare MCR
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
Awards
- Elected Member
Education
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UCSF -
Jefferson Medical College
Hospital
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UCSF Medical Center
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1033159280 |
| Last Name Of The Provider | NADEL |
| First Name Of The Provider | JAY |
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