Professor, Pathology and Immunology, Baylor College of Medicine
Pathology
Dr. James Versalovic, MD
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James Versalovic works in the field of Pathology. He studied medicine at Baylor College of Medicine. He received awards:"Fellow (AGAF)". Dr. James Versalovic is a published doctor. He has 100 publications published. The most current publication "Identification of a 23S rRNA gene mutation in clarithromycin-resistant Helicobacter pylori."
Publications
- The preterm placental microbiome varies in association with excess maternal gestational weight gain.
- Draft genome sequences and description of Lactobacillus rhamnosus strains L31, L34, and L35.
- The airway microbiome of intubated premature infants: characteristics and changes that predict the development of bronchopulmonary dysplasia.
- From prediction to function using evolutionary genomics: Human-specific ecotypes of Lactobacillus reuteri have diverse probiotic functions.
- The placenta harbors a unique microbiome.
- Helicobacter hepaticus Cholesterol-α-glucosyltransferase is Essential for Establishing Colonization in Male A/JCr Mice.
- Identification of a proton-chloride antiporter (EriC) by Himar1 transposon mutagenesis in Lactobacillus reuteri and its role in histamine production.
- Helminth co-infection in Helicobacter pylori infected INS-GAS mice attenuates gastric premalignant lesions of epithelial dysplasia and glandular atrophy and preserves ...
- Gut microbiota influences low fermentable substrate diet efficacy in children with irritable bowel syndrome.
- Compositional and Functional Features of the Gastrointestinal Microbiome and Their Effects on Human Health.
- Identification of Lactobacillus strains with probiotic features from the bottlenose dolphin (Tursiops truncatus).
- Significant Morbidity and Mortality Attributable to Rothia Mucilaginosa Infections in Children with Hematological Malignancies or Following Hematopoietic Stem Cell Tra...
- Molecular epidemiological surveillance of multidrug-resistant Pseudomonas aeruginosa isolates in a pediatric population of patients with cystic fibrosis and determinat...
- Cellulose supplementation early in life ameliorates colitis in adult mice.
- The Human Gut Microbiome and Body Metabolism: Implications for Obesity and Diabetes.
- The Genboree Microbiome Toolset and the analysis of 16S rRNA microbial sequences.
- Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation.
- The intestinal microbiome, probiotics and prebiotics in neurogastroenterology.
- The Human Microbiome Project strategy for comprehensive sampling of the human microbiome and why it matters.
- A metagenomic approach to characterization of the vaginal microbiome signature in pregnancy.
- The human microbiome and probiotics: implications for pediatrics.
- The generation of narrative interpretations in laboratory medicine: a description of service-specific sign-out rounds.
- Molecular evidence of Helicobacter cinaedi organisms in human gastric biopsy specimens.
- Molecular resistance testing of Helicobacter pylori in gastric biopsies.
- Frameshift mutations in rdxA and metronidazole resistance in North American Helicobacter pylori isolates.
- Helicobacter aurati sp. nov., a urease-positive Helicobacter species cultured from gastrointestinal tissues of Syrian hamsters.
- Identification of a 23S rRNA gene mutation in clarithromycin-resistant Helicobacter pylori.
- Point mutations in the 23S rRNA gene of Helicobacter pylori associated with different levels of clarithromycin resistance.
- A PCR-oligonucleotide ligation assay to determine the prevalence of 23S rRNA gene mutations in clarithromycin-resistant Helicobacter pylori.
- Missense mutations in the 3'' end of the Escherichia coli dnaG gene do not abolish primase activity but do confer the chromosome-segregation-defective (par) phenotype.
- Molecular typing of Helicobacter pylori isolates from a multicenter U.S. clinical trial by ureC restriction fragment length polymorphism.
- Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori.
- Differential subsequence conservation of interspersed repetitive Streptococcus pneumoniae BOX elements in diverse bacteria.
- Vertical transmission of Citrobacter diversus documented by DNA fingerprinting.
- Penicillin-resistant Streptococcus pneumoniae strains recovered in Houston: identification and molecular characterization of multiple clones.
- Whole-cell repetitive element sequence-based polymerase chain reaction allows rapid assessment of clonal relationships of bacterial isolates.
- Conservation and evolution of the rpsU-dnaG-rpoD macromolecular synthesis operon in bacteria.
- The Haemophilus influenzae dnaG sequence and conserved bacterial primase motifs.
- DNA-based identification and epidemiologic typing of bacterial pathogens.
- Characterization of the macromolecular synthesis (MMS) operon from Listeria monocytogenes.
- DNA fingerprinting of pathogenic bacteria by fluorophore-enhanced repetitive sequence-based polymerase chain reaction.
- Molecular epidemiology of infections due to Enterobacter aerogenes: identification of hospital outbreak-associated strains by molecular techniques.
- Cluster analysis of Helicobacter pylori genomic DNA fingerprints suggests gastroduodenal disease-specific associations.
- Mutations in the Escherichia coli dnaG gene suggest coupling between DNA replication and chromosome partitioning.
- Use of the polymerase chain reaction for physical mapping of Escherichia coli genes.
- Distribution of repetitive DNA sequences in eubacteria and application to fingerprinting of bacterial genomes.
- Analysis of relationships among isolates of Citrobacter diversus by using DNA fingerprints generated by repetitive sequence-based primers in the polymerase chain react...
- Rapid mapping of Escherichia coli::Tn5 insertion mutations by REP-Tn5 PCR.
- Genotypic and phenotypic studies of murine intestinal lactobacilli: species differences in mice with and without colitis.
- HIV update. Diagnostic tests and markers of disease progression and response to therapy.
- Is real-time detection of drug-resistant Staphylococcus aureus worth considering?
- Lactobacillus rhamnosus GG decreases TNF-alpha production in lipopolysaccharide-activated murine macrophages by a contact-independent mechanism.
- Helicobacter pylori. Pathology and diagnostic strategies.
- Molecular detection and genotyping of pathogens: more accurate and rapid answers.
- Differences in laboratory findings for cerebrospinal fluid specimens obtained from patients with meningitis or encephalitis due to herpes simplex virus (HSV) documente...
- Molecular assays in the diagnosis of neonatal sepsis: a systematic review and meta-analysis.
- Human microbiome in health and disease.
- Farnesol decreases biofilms of Staphylococcus epidermidis and exhibits synergy with nafcillin and vancomycin.
- Functional identification in Lactobacillus reuteri of a PocR-like transcription factor regulating glycerol utilization and vitamin B12 synthesis.
- Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome.
- Cyclopropane fatty acid synthase mutants of probiotic human-derived Lactobacillus reuteri are defective in TNF inhibition.
- Exploring metabolic pathway reconstruction and genome-wide expression profiling in Lactobacillus reuteri to define functional probiotic features.
- Lactobacillus reuteri promotes Helicobacter hepaticus-associated typhlocolitis in gnotobiotic B6.129P2-IL-10(tm1Cgn) (IL-10(-/-) ) mice.
- Colonic mucosal DNA methylation, immune response, and microbiome patterns in Toll-like receptor 2-knockout mice.
- Rapid stool-based diagnosis of Clostridium difficile infection by real-time PCR in a children's hospital.
- Probiotics, enteric and diarrheal diseases, and global health.
- Molecular microbiological methods in the diagnosis of neonatal sepsis.
- Probiotics-host communication: Modulation of signaling pathways in the intestine.
- Hospital-acquired Staphylococcus aureus infections at Texas Children's Hospital, 2001-2007.
- Novel synergistic antibiofilm combinations for salvage of infected catheters.
- Targeting the human microbiome with antibiotics, probiotics, and prebiotics: gastroenterology enters the metagenomics era.
- Vancomycin MICs for Staphylococcus aureus vary by detection method and have subtly increased in a pediatric population since 2005.
- Arrays and medical microbiology: e pluribus unum.
- National Institutes of Health Gastrointestinal Microbiota and Advances in Prebiotic and Probiotic Research conference summary.
- Fur-independent induction of Helicobacter pylori flavodoxin-encoding gene (fldA) under iron starvation.
- Probiotics and gastrointestinal infections.
- Metagenomic pyrosequencing and microbial identification.
- Mechanisms of probiosis and prebiosis: considerations for enhanced functional foods.
- Lactobacillus saerimneri and Lactobacillus ruminis: novel human-derived probiotic strains with immunomodulatory activities.
- Probiotic Lactobacillus reuteri biofilms produce antimicrobial and anti-inflammatory factors.
- Ethical, legal, and social considerations in conducting the Human Microbiome Project.
- Relationships among ciprofloxacin, gatifloxacin, levofloxacin, and norfloxacin MICs for fluoroquinolone-resistant Escherichia coli clinical isolates.
- Probiotic prophylaxis in predicted severe acute pancreatitis.
- Infectious diseases testing.
- Probiotic Lactobacillus reuteri suppress proinflammatory cytokines via c-Jun.
- Human-derived probiotic Lactobacillus reuteri demonstrate antimicrobial activities targeting diverse enteric bacterial pathogens.
- DNA pyrosequencing-based identification of pathogenic Candida species by using the internal transcribed spacer 2 region.
- Probiotic Lactobacillus reuteri promotes TNF-induced apoptosis in human myeloid leukemia-derived cells by modulation of NF-kappaB and MAPK signalling.
- Genomic and genetic characterization of the bile stress response of probiotic Lactobacillus reuteri ATCC 55730.
- Probiotics: intestinal gatekeeping, immunomodulation, and hepatic injury.
- Expanding the diagnostic capabilities of molecular microbiology by genomic methods.
- DNA pyrosequencing-based bacterial pathogen identification in a pediatric hospital setting.
- Clinical laboratory reports in molecular pathology.
- The early response to acid shock in Lactobacillus reuteri involves the ClpL chaperone and a putative cell wall-altering esterase.
- Helicobacter hepaticus catalase shares surface-predicted epitopes with mammalian catalases.
- Widespread outbreak of norovirus gastroenteritis among evacuees of Hurricane Katrina residing in a large "megashelter" in Houston, Texas: lessons learned for prevention.
- How bacterial communities expand functional repertoires.
- Emerging technologies for emerging infections.
- Colonic Mucosal Epigenome and Microbiome Development in Children and Adolescents.
Schools
Baylor University
Mass Gen Hospital
Doctors Specialties
- Molecular Genetic Pathology
- Pathology
Accepted Insurances
Awards
- Fellow (AGAF)
Education
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Massachusetts General Hospital -
Baylor College of Medicine
Hospital
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Texas Children's Hospital
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