Chairman, Department of Pathology, UTSW
Pathology
Dr. James S. Malter, MD
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James Malter works in the field of Pathology. He went to medical school at Washington University School of Medicine in St. Louis. He received 1 awards: "Elected Member". James Malter is a published doctor and has 101 publications published. The lastest was: 'Stabilization of granulocyte-macrophage colony-stimulating factor RNA in a human eosinophil-like cell line requires the AUUUA motifs.'
Publications
- IL-3 Maintains Activation of the p90S6K/RPS6 Pathway and Increases Translation in Human Eosinophils.
- Determinants of eosinophil survival and apoptotic cell death.
- Semaphorin 7A is expressed on airway eosinophils and upregulated by IL-5 family cytokines.
- Pin1-FADD Interactions Regulate Fas-Mediated Apoptosis in Activated Eosinophils.
- Soy-based diet exacerbates seizures in mouse models of neurological disease.
- Reversal of fragile X phenotypes by manipulation of A?PP/A? levels in Fmr1KO mice.
- Preparation of Synaptoneurosomes from Mouse Cortex using a Discontinuous Percoll-Sucrose Density Gradient.
- The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-alpha-induced priming of the NADPH oxidase in human neutrophils.
- Plasma exchange after initial intravenous immunoglobulin treatment in Guillain-Barré syndrome: critical reassessment of effectiveness and cost-efficiency.
- Pin1 and PKMzeta sequentially control dendritic protein synthesis.
- Rck/p54 interacts with APP mRNA as part of a multi-protein complex and enhances APP mRNA and protein expression in neuronal cell lines.
- N-Acetylcysteine Prevents 4-Hydroxynonenal- and Amyloid-beta-Induced Modification and Inactivation of Neprilysin in SH-SY5Y Cells.
- The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.
- MPEP reduces seizure severity in Fmr-1 KO mice over expressing human Abeta.
- Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study.
- Thymic stromal lymphopoietin expression in allergic pulmonary inflammation is Pin1-dependent.
- Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis.
- Pinning down signaling in the immune system: the role of the peptidyl-prolyl isomerase Pin1 in immune cell function.
- Seizure susceptibility and mortality in mice that over-express amyloid precursor protein.
- Tissue transglutaminase, protein cross-linking and Alzheimer's disease: review and views.
- Thymic stromal lymphopoietin (TSLP) as a bridge between infection and atopy.
- A critical role for Pin1 in allergic pulmonary eosinophilia in rats.
- Antisense targeting of TGF-beta1 augments BMP-induced upregulation of osteopontin, type I collagen and Cbfa1 in human Saos-2 cells.
- FMRP mediates mGluR5-dependent translation of amyloid precursor protein.
- Circadian changes in granulocyte-macrophage colony-stimulating factor message in circulating eosinophils.
- Pin1 modulates the type 1 immune response.
- The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes.
- Decoy mRNAs reduce beta-amyloid precursor protein mRNA in neuronal cells.
- beta-Amyloid degradation and Alzheimer's disease.
- The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils.
- HuR mRNA ligands expressed after seizure.
- Dendritic cell-based immunotherapy for cancer and relevant challenges for transfusion medicine.
- Expression of interleukin-5- and granulocyte macrophage-colony-stimulating factor-responsive genes in blood and airway eosinophils.
- Ets-1 regulates TNF-alpha-induced matrix metalloproteinase-9 and tenascin expression in primary bronchial fibroblasts.
- Anti-Abeta: The good, the bad, and the unforeseen.
- Hyaluronic acid or TNF-alpha plus fibronectin triggers granulocyte macrophage-colony-stimulating factor mRNA stabilization in eosinophils yet engages differential intr...
- The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95.
- Serum and low-density lipoprotein enhance interleukin-8 secretion by airway epithelial cells.
- Fragile X mental retardation protein in plasticity and disease.
- Extracellular signal-regulated kinase mediates granulocyte-macrophage colony-stimulating factor messenger RNA stabilization in tumor necrosis factor-alpha plus fibrone...
- Phosphate-Induced Renal Fibrosis Requires the Prolyl Isomerase Pin1.
- Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours.
- Identification of genes expressed by human airway eosinophils after an in vivo allergen challenge.
- Pin1 Null Mice Exhibit Low Bone Mass and Attenuation of BMP Signaling.
- Regulation of mRNA stability in the nervous system and beyond.
- Y box-binding factor promotes eosinophil survival by stabilizing granulocyte-macrophage colony-stimulating factor mRNA.
- Extracellular-regulated kinase controls beta-amyloid precursor protein mRNA decay.
- Granulocyte macrophage-colony-stimulating factor mRNA is stabilized in airway eosinophils and peripheral blood eosinophils activated by TNF-alpha plus fibronectin.
- Granulocyte macrophage colony-stimulating factor and interleukin-5 activate STAT5 and induce CIS1 mRNA in human peripheral blood eosinophils.
- Minute quantities of granulocyte-macrophage colony-stimulating factor prolong eosinophil survival.
- Up-regulation of nucleolin mRNA and protein in peripheral blood mononuclear cells by extracellular-regulated kinase.
- Growth factor-mediated stabilization of amyloid precursor protein mRNA is mediated by a conserved 29-nucleotide sequence in the 3'-untranslated region.
- Primary peripheral blood eosinophils rapidly degrade transfected granulocyte-macrophage colony-stimulating factor mRNA.
- Calcium ionophore upregulation of AUUUA-specific binding protein activity is contemporaneous with granulocyte macrophage colony-stimulating factor messenger RNA stabil...
- The 5''-untranslated region of GM-CSF mRNA suppresses translational repression mediated by the 3'' adenosine-uridine-rich element and the poly(A) tail.
- Identification of AUF-1 ligands reveals vast diversity of early response gene mRNAs.
- Stabilization of granulocyte-macrophage colony-stimulating factor RNA in a human eosinophil-like cell line requires the AUUUA motifs.
- Pediatric anti-glomerular basement membrane glomerulonephritis.
- hnRNP C increases amyloid precursor protein (APP) production by stabilizing APP mRNA.
- Posttranscriptional regulation of mRNAs important in T cell function.
- Regulation of eukaryotic messenger RNA turnover.
- Cytoplasmic fate of eukaryotic mRNA: identification and characterization of AU-binding proteins.
- Particle-mediated gene transfer of granulocyte-macrophage colony-stimulating factor cDNA to tumor cells: implications for a clinically relevant tumor vaccine.
- In vivo particle-mediated cytokine gene transfer into canine oral mucosa and epidermis.
- Turnover and translation of in vitro synthesized messenger RNAs in transfected, normal cells.
- AUUUA-specific mRNA binding proteins in astrocytes.
- Association of heterogeneous nuclear ribonucleoprotein A1 and C proteins with reiterated AUUUA sequences.
- Amyloid precursor protein mRNA stability is controlled by a 29-base element in the 3'-untranslated region.
- Multiple proteins interact at a unique cis-element in the 3'-untranslated region of amyloid precursor protein mRNA.
- Modulation of granulocyte-macrophage colony-stimulating factor mRNA stability in vitro by the adenosine-uridine binding factor.
- Post-transcriptional regulation of the p53 tumor suppressor gene during growth-induction of human peripheral blood mononuclear cells.
- Granulocyte-macrophage colony-stimulating factor mRNA stabilization enhances transgenic expression in normal cells and tissues.
- Nucleolin and heterogeneous nuclear ribonucleoprotein C proteins specifically interact with the 3'-untranslated region of amyloid protein precursor mRNA.
- Role of aminoacylation of histidyl-tRNA in the regulation of protein degradation in Chinese hamster ovary cells.
- Identification of hyperthyroid patients by means of a sensitive assay for thyrotropin.
- Induction and regulation of CD2 mRNA in human lymphocytes.
- Identification of an AUUUA-specific messenger RNA binding protein.
- Regulation of hepatocyte gene expression: progress on the horizon.
- Detection of hepatitis B virus DNA in formalin-fixed, paraffin-embedded liver tissue by the polymerase chain reaction.
- Human papillomavirus type 18 in conjunctival intraepithelial neoplasia.
- Adenosine-uridine binding factor requires metals for binding to granulocyte-macrophage colony-stimulating factor mRNA.
- The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs.
- A redox switch and phosphorylation are involved in the post-translational up-regulation of the adenosine-uridine binding factor by phorbol ester and ionophore.
- Flow cytometry measurements of the DNA content of corneal epithelial cells during wound healing.
- The polymerase chain reaction for hepatitis B virus DNA.
- Detection of CD2 polymorphism on chromosome 1 with EcoRI.
- Regulation of mRNA stability and its relevance to disease.
- A rapid and inexpensive method for the addition of poly A coding tracts to transcription vectors.
- Reconstitution of an active surface CD2 by DNA transfer in CD2-CD3+ Jurkat cells facilitates CD3-T cell receptor-mediated IL-2 production.
- Development and application of an in vitro model for screening anti-hepatitis B virus therapeutics.
- Hypoxia up-regulates the activity of a novel erythropoietin mRNA binding protein.
- EGF cell surface receptor quantitation on ocular cells by an immunocytochemical flow cytometry technique.
- Zidovudine-induced blockade of the expression and function of the erythropoietin receptor.
- Detection of hepatitis C virus RNA sequences by polymerase chain reaction in fixed liver tissue.
- Tumor necrosis factor alpha-induced glucose transporter (GLUT-1) mRNA stabilization in 3T3-L1 preadipocytes. Regulation by the adenosine-uridine binding factor.
- Fragile X Syndrome and Alzheimer''s Disease: Another story about APP and beta-amyloid.
- RhoB mRNA is stabilized by HuR after UV light.
- The significance of Pin1 in the development of Alzheimer''s disease.
- Effects of 4-hydroxy-nonenal and Amyloid-beta on expression and activity of endothelin converting enzyme and insulin degrading enzyme in SH-SY5Y cells.
- Effects of HNE-modification induced by Abeta on neprilysin expression and activity in SH-SY5Y cells.
Schools
Washington Center School of Medicine
Hospital Of The University Of Pennsylvania
Doctors Specialties
- Pathology
Accepted Insurances
Awards
- Elected Member
Education
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University of Pennsylvania Health System -
Washington University School of Medicine in St. Louis
Hospital
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University of Texas Southwestern Medical Center
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