Professor of Medicine, University MO-Columbia School of Medicine
Endocrinology
Dr. James R. Sowers, MD
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James R. Sowers practices Endocrinology. He attended University of Alabama Medical Center. University of Alabama Medical Center has a rank of 37 in research and a 17 in primary care He has 3 awards "America's Top Doctors", "Men's Health" and "Elected Member". James Sowers is a published doctor. He published 98 publications, including: 'A Possible New Multiple Endocrine Neoplasia Mutation in a Patient with a Prototypic Multiple Endocrine Neoplasia Presentation.' Doctor James R. Sowers, MD accepts all Medicare patients.
Publications
- Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy.
- Endothelial Mineralocorticoid Receptor Mediates Diet Induced Aortic Stiffness in Females.
- A Possible New Multiple Endocrine Neoplasia Mutation in a Patient with a Prototypic Multiple Endocrine Neoplasia Presentation.
- Endothelial estrogen receptor alpha does not protect against vascular stiffness induced by Western Diet in female mice.
- Caveolin-1 in Cardiovascular Disease: A Double-Edged Sword.
- Treating NAFLD in OLETF Rats with Vigorous-Intensity Interval Exercise Training.
- Mineralocorticoid Receptor Blockade Prevents Western Diet-induced Diastolic Dysfunction in Female Mice.
- Mitochondrial functional impairment in response to environmental toxins in the cardiorenal metabolic syndrome.
- Autoantibodies of β-adrenergic and M2 cholinergic receptors: atrial fibrillation in Hyperthyroidism.
- Mineralocorticoid Receptor Antagonism Treats Obesity-Associated Cardiac Diastolic Dysfunction.
- Mineralocorticoid receptors: an appealing target to treat coronary microvascular dysfunction in Diabetes.
- Dipeptidyl peptidase-4 inhibition ameliorates western diet-induced hepatic steatosis and insulin resistance through hepatic Lipid remodeling and modulation of hepatic ...
- Insulin resistance and skeletal muscle vasculature: significance, assessment and therapeutic modulators.
- Interaction of Islet α-Cell and β-Cell in the Regulation of Glucose Homeostasis in HI/HA Syndrome Patients With the GDHH454Y Mutation.
- Application of a novel curcumin analog in the management of diabetic cardiomyopathy.
- Endothelial Dysfunction Potentially Interacts With Impaired Glucose Metabolism to Increase Cardiovascular Risk.
- Invited Review: Over-nutrition, mTOR Signaling and Cardiovascular Diseases.
- DPP4 Inhibition attenuates filtration barrier injury and oxidant stress in the zucker obese rat.
- Pleiotropic Effects of the Dipeptidylpeptidase-4 Inhibitors on the Cardiovascular System.
- Autophagy: A housekeeper in cardiorenal metabolic health and disease.
- Fructose and uric Acid: is there a role in endothelial function?
- Cervical neuroendocrine tumor in a young female with Lynch Syndrome.
- The pathophysiology of hypertension in patients with obesity.
- Salt Loading Promotes Kidney Injury via Fibrosis in Young Female Ren2 Rats.
- Dipeptidyl peptidase inhibition prevents diastolic dysfunction and reduces myocardial fibrosis in a Mouse model of Western diet induced obesity.
- Type 2 Diabetes Mellitus and Hypertension: An Update.
- Thyroid and the Heart.
- New insights into insulin action and resistance in the vasculature.
- New thoughts in an old player: role of nitrite in the treatment of ischemic revascularization.
- Implications for glucose measures in the Diabetes control and complications trial/epidemiology of Diabetes interventions and complications study.
- Combining Metformin and Aerobic Exercise Training in the Treatment of Type 2 Diabetes and NAFLD in OLETF Rats.
- Cardiorenal metabolic syndrome and diabetic cognopathy.
- Diabetic kidney disease and the cardiorenal syndrome: old disease, new perspectives.
- Uric Acid - Key Ingredient in the Recipe for Cardiorenal Metabolic Syndrome.
- Obesity and insulin resistance induce early development of diastolic dysfunction in young female mice fed a Western diet.
- Salt loading exacerbates diastolic dysfunction and cardiac remodeling in young female Ren2 rats.
- Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance.
- The Novel Angiotensin II Receptor Blocker Azilsartan Medoxomil Ameliorates Insulin Resistance Induced by Chronic Angiotensin II Treatment in Rat Skeletal Muscle.
- Type 2 Diabetes in older people; the importance of blood pressure control.
- Dipeptidylpeptidase Inhibition is Associated with Improvement in Blood Pressure and Diastolic Function in Insulin Resistant Male Zucker Obese Rats.
- Diabetes mellitus and vascular disease.
- Metabolic Impact of Adding a Thiazide Diuretic to Captopril.
- Mineralocorticoid receptor-mediated vascular insulin resistance: an early contributor to Diabetes-related vascular disease?
- Angiotensin Type 1 Receptor Resistance To Blockade In The Opossum Proximal Tubule Cell Due To Variations In The Binding Pocket.
- Randomized Study of Antihypertensive Efficacy and Safety of Combination Aliskiren/Valsartan vs Valsartan Monotherapy in Hypertensive Participants With Type 2 Diabetes ...
- Therapy of obese patients with cardiovascular disease.
- Renin Inhibition and AT(1)R blockade improve metabolic signaling, oxidant stress and myocardial tissue remodeling.
- Role of insulin resistance in endothelial dysfunction.
- Obesity and the Cardiorenal Metabolic Syndrome: Therapeutic Modalities and Their Efficacy in Improving Cardiovascular and Renal Risk Factors.
- RAS-Mediated Adaptive Mechanisms in Cardiovascular Tissues: Confounding Factors of RAS Blockade Therapy and Alternative Approaches.
- Phosphoprotein Phosphatase PP2A Regulation of Insulin Receptor Substrate 1 and Insulin Metabolic Signaling.
- Hypertension: Synergy of antihypertensives in elderly patients with CKD.
- Molecular and metabolic mechanisms of cardiac dysfunction in Diabetes.
- Obesity-related alterations in cardiac Lipid profile and nondipping blood pressure pattern during transition to diastolic dysfunction in male db/db mice.
- Insulin resistance and heart failure: molecular mechanisms.
- Nebivolol reduces cardiac angiotensin II, associated oxidative stress and fibrosis but not arterial pressure in salt-loaded spontaneously hypertensive rats.
- Oxidative stress in the cardiorenal metabolic syndrome.
- Initial Choice of Antihypertensive on Long-Term Cardiovascular Outcomes in CKD.
- Gestational Diabetes and the Offspring: Implications in the Development of the Cardiorenal Metabolic Syndrome in Offspring.
- The kaliuretic impact of cicletanine compared to hydrochlorothiazide.
- Over-nutrition and metabolic cardiomyopathy.
- Combination of direct renin inhibition with angiotensin Type 1 receptor blockade improves aldosterone but does not improve kidney injury in the transgenic Ren2 rat.
- NEBIVOLOL IMPROVES DIASTOLIC DYSFUNCTION AND MYOCARDIAL REMODELING THROUGH REDUCTIONS IN OXIDATIVE STRESS IN THE TRANSGENIC (MREN2) RAT.
- A Case of Carcinoid Tumor-Associated Hypercalcemia.
- Ultrastructure Study of Transgenic Ren2 Rat Aorta - Part 1: Endothelium and Intima.
- Antihypertensive and Metabolic Effects of Angiotensin Receptor Blocker/Diuretic Combination Therapy in Obese, Hypertensive African American and White Patients.
- Cardiac Insulin Resistance and MicroRNA Modulators.
- Aldosterone and Risk for Insulin Resistance.
- Activation of mTOR/p70S6 Kinase by ANG II Inhibits Insulin Stimulated Endothelial Nitric Oxide Synthase and Vasodilation.
- Indices of Obesity and Cardiometabolic Risk.
- Office and ambulatory blood pressure-lowering effects of combination valsartan/hydrochlorothiazide vs. hydrochlorothiazide-based therapy in obese, hypertensive patients.
- Hypertension in obesity.
- Sex differences in baroreflex sensitivity, heart rate variability, and end organ damage in the TGR(mRen2)27 rat.
- Adaptive mechanisms to compensate for overnutrition-induced cardiovascular abnormalities.
- Angiotensin II activation of mTOR results in tubulointerstitial fibrosis through loss of N-cadherin.
- Bariatric Surgery Reduces Visceral Adipose Inflammation and Improves Endothelial Function in Type 2 Diabetic Mice.
- Nebivolol improves insulin sensitivity in the TGR(Ren2)27 rat.
- Moderate versus intensive treatment of hypertension using amlodipine/valsartan and with the addition of hydrochlorothiazide for patients uncontrolled on angiotensin re...
- Mineralocorticoid receptor blockade improves diastolic function independent of blood pressure reduction in a transgenic model of RAAS overexpression.
- Nebivolol attenuates redox-sensitive glomerular and tubular mediated proteinuria in obese rats.
- The Role of Overweight and Obesity in the Cardiorenal Syndrome.
- The Heart and the Kidneys: Partners in Disease?
- Central Pressure and Biomarker Responses to Renin Inhibition with Hydrochlorothiazide and Ramipril in Obese Hypertensives: The ATTAIN Study.
- Prenatal Programming and Epigenetics in the Genesis of the Cardiorenal Syndrome.
- Possible Mechanisms of Local Tissue Renin-Angiotensin System Activation in the Cardiorenal Metabolic Syndrome and Type 2 Diabetes Mellitus.
- Overnutrition and the Cardiorenal Syndrome: Use of a Rodent Model to Examine Mechanisms.
- The Impact of Overnutrition on Insulin Metabolic Signaling in the Heart and the Kidney.
- Comparative analysis of telmisartan and olmesartan on cardiac function in the transgenic (mRen2)27 rat.
- Phosphate Metabolism in Cardiorenal Metabolic Disease.
- The role of oxidative stress in the metabolic syndrome.
- Gestational Diabetes mellitus alone in the absence of subsequent Diabetes is associated with microalbuminuria: results from the Kidney Early Evaluation Program (KEEP).
- Resistant hypertension in office practice: a clinical approach.
- Retinal redox stress and remodeling in cardiometabolic syndrome and Diabetes.
- Pericytopathy: oxidative stress and impaired cellular longevity in the pancreas and skeletal muscle in metabolic syndrome and type 2 Diabetes.
- Surgical cure of hypertension in a patient with MEN 2A syndrome and mixed dopamine, metanephrine pheochromocytoma.
- Cytokine abnormalities in the etiology of the cardiometabolic syndrome.
- Best strategies for hypertension management in type 2 Diabetes and obesity.
Schools
University Of Missouri Columbia Campus
St Johns Mercy Med Center
University Of Al Hospital
Vet Affairs Med Center W La
Conditions Treated
- Calcium Metabolism Disorders
- Diabetes Type 1
- Diabetes Type 2
- Goiter
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Doctors Specialties
- Endocrinology
Accepted Insurances
Awards
- America's Top Doctors
- Men's Health
- Elected Member
Education
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VA Greater Los Angeles Healthcare System -
University of Alabama Medical Center -
University of Missouri-Columbia School of Medicine
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1699729350 |
| Last Name Of The Provider | SOWERS |
| First Name Of The Provider | JAMES |
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