Physician

Anesthesiology

James Robotham works in the field of Anesthesiology. He studied medicine at Boston University School of Medicine. Boston University School of Medicine has a rank of 30 in research and a 52 in primary care He has 1 awards "Top MD". Doctor James L. Robotham, MD is also a published physician. He has 50 paper published. The most recent paper is: Potential paracrine role of the pericardium in the regulation of cardiac function.

Publications

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• Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology.
• Lung-marginated monocytes modulate pulmonary microvascular injury during early endotoxemia.
• Calcium, ATP, and ROS: a mitochondrial love-hate triangle.
• Mechanisms of blood flow during pneumatic vest cardiopulmonary resuscitation.
• Effects of changes in left ventricular loading and pleural pressure on mitral flow.
• Mitral and aortic blood flows during spontaneous respiration in dogs.
• Pressure-flow analysis of portal vein and hepatic artery interactions in porcine liver.
• Endothelin causes portal and pulmonary hypertension in porcine endotoxemic shock.
• Effects of endotoxin on isolated porcine liver: pressure-flow analysis.
• Dysregulation of the veno-arterial response in the superior mesenteric artery during endotoxic shock.
• The acute-phase response.
• Hepatic heat shock and acute-phase gene expression are induced simultaneously after celiotomy in the anesthetized pig.
• Endotoxic shock alters distribution of blood flow within the intestinal wall.
• A physiologic assessment of segmental bronchial atresia.
• Inhibition of myocardial crossbridge cycling by hypoxic endothelial cells: a potential mechanism for matching oxygen supply and demand?
• Regulation of acute phase gene expression following surgery and endotoxin administration in the anesthetized pig.
• Airway obstruction during sleep increases blood pressure without arousal.
• Systemic and pulmonary hemodynamic responses to normal and obstructed breathing during sleep.
• Neural and local effects of hypoxia on cardiovascular responses to obstructive apnea.
• Left ventricular geometry during positive end-expiratory pressure in dogs.
• Left ventricular hemodynamics during respiration.
• Effects of PEEP on liver arterial and venous blood flows.
• Effects of positive and negative pressure ventilation on cardiac performance.
• Coupled vs. uncoupled pericardial constraint: effects on cardiac chamber interactions.
• Effect of aminophylline on high-energy phosphate metabolism and fatigue in the diaphragm.
• Diaphragmatic fatigue assessed by 31P-magnetic resonance spectroscopy in vivo.
• Ejection fraction revisited.
• Transient analysis of cardiopulmonary interactions. II. Systolic events.
• Effect of anesthesia and surgery on plasma cytokine levels.
• Transient analysis of cardiopulmonary interactions. I. Diastolic events.
• Regional control of venous return: liver blood flow.
• Reflex stimulation of renal sympathetic nerve activity and blood pressure in response to apnea.
• Endotoxin induces organ-specific endothelial cell injury.
• Effects of inspiratory diaphragmatic descent on inferior vena caval venous return.
• Effects of abdominal pressure on venous return: abdominal vascular zone conditions.
• Relationship of diaphragmatic contractility to diaphragmatic blood flow in newborn lambs.
• Distinct behavior of portal venous and arterial vascular waterfalls in porcine liver.
• Correlation of left phrenic arterial flow with regional diaphragmatic blood flow.
• Influence of the pericardium on ventricular loading during respiration.
• Ventricular external constraint by the lung and pericardium during positive end-expiratory pressure.
• Influence of pericardial constraint on atrioventricular interactions.
• Superior and inferior vena caval flows during respiration: pathogenesis of Kussmaul's sign.
• Right and left ventricular cultured endocardial endothelium produces prostacyclin and PGE2.
• Paracrine effects of endocardial endothelial cells on myocyte contraction mediated via endothelin.
• Potential paracrine role of the pericardium in the regulation of cardiac function.
• Bronchodilator premedication does not decrease respiratory adverse events in pediatric general anesthesia.
• Saline volume expansion and cardiovascular physiology: novel observations, old explanations, and new questions.
• Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species.
• Mitochondria: new drug targets for oxidative stress-induced diseases.

Schools

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• Boston University School Of Medicine

• Boston City Hospital

• Johns Hopkins Hospital

• The Hospital Sick Children

Doctors Specialties

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• Pediatric Critical Care Medicine
• Anesthesiology

Accepted Insurances

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Awards

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• Top MD

Education

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• Johns Hopkins University
• Boston University Medical Center
• Boston University School of Medicine

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