Associate Professor of Surgery, Massachusetts General Hospital
General Surgery
Dr. James C. Cusack Jr., MD
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Dr. James C. Cusack Jr. works in the field of General Surgery. He studied medicine at Emory University School of Medicine. Emory University School of Medicine has a rank of 23 in research and a 42 in primary care He received 2 awards: "Super Doctor" and "Fellow (FACS)". James Cusack is a published doctor as well. He has 53 publications published. The latest was: Cancer gene therapy. He is registered with Medicare.
Publications
- Building a Global Surgery Initiative Through Evaluation, Collaboration, and Training: The Massachusetts General Hospital Experience.
- A Critical Look at Local-Regional Management of Peritoneal Metastasis.
- Clinical and treatment factors associated with vaginal stenosis after definitive chemoradiation for anal canal Cancer.
- Current Status of Imaging and Emerging Techniques to Evaluate Liver Metastases From ColoRectal Carcinoma.
- Targeting the NF-κB Pathway in Cancer Therapy.
- Mutational and Clinical Predictors of Pathologic Complete Response in the Treatment of Locally Advanced Rectal Cancer.
- CRM1 and BRAF inhibition synergize and induce tumor regression in BRAF mutant melanoma.
- Concurrent chemotherapy inhibits herpes simplex virus-1 replication and oncolysis.
- Merkel Cell Carcinoma: 30-Year Experience from a Single Institution.
- Managing patients at high risk for hereditary breast Cancer: a guide for the practicing physician.
- Hereditary Breast and Ovarian Cancer and Other Hereditary Syndromes: Using Technology to Identify Carriers.
- Activation of PI3K signaling in Merkel cell carcinoma.
- Case records of the Massachusetts General Hospital. Case 13-2011. A 49-year-old man with adenocarcinoma of the rectum.
- Case records of the Massachusetts General Hospital: Case 3-2011: a 58-year-old woman with a mass in the Liver.
- The effect of neoadjuvant chemoradiation therapy on the prognostic value of lymph nodes after rectal Cancer surgery.
- Proteasome inhibition activates epidermal growth factor receptor (EGFR) and EGFR-independent mitogenic kinase signaling pathways in pancreatic Cancer cells.
- Extra-Adrenal pheochromocytoma involving the organ of Zuckerkandl.
- Membrane-bound heparin-binding epidermal growth factor like growth factor regulates E-cadherin expression in Pancreatic carcinoma cells.
- A Phase I study of bortezomib plus irinotecan in patients with advanced solid Tumors.
- NPI-0052 enhances tumoricidal response to conventional Cancer therapy in a colon Cancer model.
- Successful minimally invasive parathyroidectomy for primary Hyperparathyroidism without using intraoperative parathyroid hormone assays.
- Overcoming antiapoptotic responses to promote chemosensitivity in metastatic colorectal Cancer to the liver.
- Clinical trials for Cancer gene therapy.
- Introduction to Cancer gene therapy.
- Advances in the treatment of Liver tumors.
- NF- kappa B and chemoresistance: potentiation of Cancer drugs via inhibition of NF- kappa B.
- Rationale for the treatment of solid Tumors with the proteasome inhibitor bortezomib.
- Antiproteasomal agents in rectal Cancer.
- Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas.
- Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition.
- Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothe cin (CPT-11) in colorectal Cancer cells and a xenograft model is overcome ...
- Heparin-binding EGF-like growth factor is an early response gene to chemotherapy and contributes to chemotherapy resistance.
- Phase I clinical trial of bortezomib in combination with gemcitabine in patients with advanced solid Tumors.
- Activation of EGFR by proteasome inhibition requires HB-EGF in pancreatic Cancer cells.
- Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB.
- Survival factors in 186 patients younger than 40 years old with coloRectal adenocarcinoma.
- Cancer gene therapy.
- Expression of human alpha(1,3)fucosyltransferase antisense sequences inhibits selectin-mediated adhesion and Liver metastasis of colon carcinoma cells.
- Multidetector-row computed tomography angiography for planning intra-arterial chemotherapy pump placement in patients with coloRectal metastases to the liver.
- Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB.
- Managing unsuspected tumor invasion of the superior mesenteric-portal venous confluence during Pancreaticoduodenectomy.
- Rationale for en bloc vein resection in the treatment of Pancreatic adenocarcinoma adherent to the superior mesenteric-portal vein confluence. Pancreatic Tumor Study G...
- In vivo adenovirus-mediated p53 tumor suppressor gene therapy for colorectal Cancer.
- Vascular resection and intraoperative radiation therapy during Pancreaticoduodenectomy: rationale and technique.
- Fas and Fas ligand interactions in malignant Disease.
- Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression.
- The influence of angiogenesis inhibitor AGM-1470 on immune system status and tumor growth in vitro.
- Reactivation of murine tumour-infiltrating lymphocytes with solid-phase anti-CD3 antibody: in vitro cytokine proDuction is associated with in vivo efficacy.
- High levels of gene transDuction in human lung tumors following intralesional injection of recombinant adenovirus.
- Role of splenectomy in chronic lymphocytic leukemia.
- Secondary cytokine proDuction by lymphoid cells used in cellular immunotherapy.
- Clinical Profiling of BCL-2 Family Members in the Setting of BRAF Inhibition Offers a Rationale for Targeting De Novo Resistance Using BH3 Mimetics.
Schools
Emory University School Of Medicine
New England Mc Hosps Tufts University School Med
Brigham and Women39s Hospital Harvard Med School
University of Texas MD Anderson Cancer Center
Procedures Preformed
- Appendectomy, Open
- Colectomy
- Cystectomy
- Cystotomy
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Conditions Treated
- Abdominal Pain
- Adrenal Gland Cancer
- Anal and Rectal Cancer
- Atelectasis
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Doctors Specialties
- General Surgery
Accepted Insurances
Awards
- Super Doctor
- Fellow (FACS)
Education
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Tufts Medical Center -
Emory University School of Medicine
Hospital
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Newton-Wellesley Hospital -
Massachusetts General Hospital
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