Professor, Medicine, Brown University Program in Medicine
Gastroenterology
Dr. Jack R. Wands, MD
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Dr. Jack R. Wands is an expert in the field of Gastroenterology. He studied medicine at University of Washington School of Medicine. Dr. Jack R. Wands is a published doctor. He has 89 publications published. The most current publication "X-ray Scatter Imaging of Hepatocellular Carcinoma in a Mouse Model Using Nanoparticle Contrast Agents." Jack Wands accepts all Medicare patients.
Publications
- Aspartate-β-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinoma.
- A highly sensitive x-ray imaging modality for hepatocellular carcinoma detection in vitro.
- Aspartate β-hydroxylase expression promotes a malignant pancreatic cellular phenotype.
- A Cell surface β-Hydroxylase is a biomarker and therapeutic target for hepatocellular carcinoma.
- LRH1 promotes pancreatic cancer metastasis.
- WNT/β-catenin signaling and hepatocellular carcinoma.
- Therapeutic reversal of chronic alcohol-related steatohepatitis with the ceramide inhibitor myriocin.
- Strain-Dependent Differences for Suppression of Insulin-Stimulated Glucose Uptake in Skeletal and Cardiac Muscle by Ethanol.
- LRH1 as a driving factor in pancreatic cancer growth.
- Role of NADPH Oxidase NOX5-S, NF-kB and DNMT1 in Acid-Induced P16 Hypermethylation in Barrett's cells.
- Wnt signaling and hepatocarcinogenesis: molecular targets for the development of innovative anticancer drugs.
- Loss of exon 4 in a human T-cell factor-4 isoform promotes hepatic tumourigenicity.
- Chronicethanol fed mice increase Treg activity and inhibit HCV core-specific cellular immune responses.
- Upregulation of T-cell factor-4 isoform-responsive target genes in hepatocellular carcinoma.
- The SxxSS motif of T-cell factor-4 isoforms modulates Wnt/?-catenin signal activation in hepatocellular carcinoma cells.
- NADPH Oxidase NOX5-S and NF-?B1 Mediate Acid-Induced Microsomal Prostaglandin Synthase-1 (Mpges1) Expression in Barrett's Esophageal Adenocarcinoma (EA) Cells.
- Chronic alcohol-induced hepatic insulin resistance and endoplasmic reticulum stress ameliorated by peroxisome-proliferator activated receptor-? agonist treatment.
- Impaired Virion Secretion by Hepatitis B Virus Immune Escape Mutants and its Rescue by Wild-Type Envelope Proteins or a Second-Site Mutation.
- Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease.
- Insulin Resistance, Ceramide Accumulation and Endoplasmic Reticulum Stress in Experimental Chronic Alcohol-Induced Steatohepatitis.
- Loss of the SxxSS Motif in a Human T-Cell Factor-4 Isoform Confers Hypoxia Resistance to Liver Cancer: An Oncogenic Switch in Wnt Signaling.
- Activated iNKT Cells Promote Memory CD8(+) T Cell Differentiation during Viral Infection.
- High fat diet induced hepatic steatosis and insulin resistance: Role of dysregulated ceramide metabolism.
- Immunization with ASPH-loaded dendritic cells produces anti-tumor effects in a rat model of intrahepatic cholangiocarcinoma.
- Limited Therapeutic Effect of N-Acetylcysteine on Hepatic Insulin Resistance in an Experimental Model of Alcohol-Induced Steatohepatitis.
- Nanomaterials for X-ray Imaging: Gold Nanoparticle Enhancement of X-ray Scatter Imaging of Hepatocellular Carcinoma.
- T1846 and A/G1913 are associated with acute on chronic liver failure in patients infected with hepatitis B virus genotypes B and C.
- Ethanol Inhibits Antigen Presentation by Dendritic Cells.
- Promising Treatment Approaches and Targets for Hepatocellular carcinoma Points of Therapeutic Intervention along the Wnt Signaling Pathway.
- Identification of T-cell factor-4 isoforms that contribute to the malignant phenotype of hepatocellular carcinoma cells.
- Role of Raf Kinase Inhibitor Protein in Hepatocellular Carcinoma.
- Impairment of hepatitis B virus virion secretion by single-amino-acid substitutions in the small envelope protein and rescue by a novel glycosylation site.
- Cytokine dependent and independent iNKT cell activation.
- Aspartyl-(asparaginyl) beta-hydroxylase, hypoxia-inducible factor-alpha and Notch cross-talk in regulating neuronal motility.
- The p85beta regulatory subunit of PI3K serves as a substrate for PTEN protein phosphatase activity during insulin mediated signaling.
- Acetaldehyde adducts in alcoholic liver disease.
- Noncanonical Wnt11 inhibits hepatocellular carcinoma cell proliferation and migration.
- Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis.
- Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death.
- PPARdelta agonist attenuates alcohol-induced hepatic insulin resistance and improves liver injury and repair.
- Overexpression of insulin receptor substrate-1 and hepatitis Bx genes causes premalignant alterations in the liver.
- Chimeric constructs between two hepatitis B virus genomes confirm transcriptional impact of core promoter mutations and reveal multiple effects of core gene mutations.
- Prognostic value of aspartyl (asparaginyl)-beta-hydroxylase/humbug expression in non-small cell lung carcinoma.
- Hepatitis C virus and alcohol.
- Ethanol inhibition of aspartyl-asparaginyl-beta-hydroxylase in fetal alcohol spectrum disorder: potential link to the impairments in central nervous system neuronal mi...
- Generation of immune responses against hepatitis C virus by dendritic cells containing NS5 protein-coated microparticles.
- Expression of apolipoprotein C-IV is regulated by Ku antigen/peroxisome proliferator-activated receptor gamma complex and correlates with liver steatosis.
- Alzheimer's disease is type 3 diabetes-evidence reviewed.
- The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cells.
- Uncoupling protein-2 modulates the lipid metabolic response to fasting in mice.
- Acute ethanol exposure inhibits insulin signaling in the liver.
- Nitric oxide synthase 3-mediated neurodegeneration after intracerebral gene delivery.
- Chronic ethanol consumption impairs cellular immune responses against HCV NS5 protein due to dendritic cell dysfunction.
- Role of aspartyl-(asparaginyl) beta-hydroxylase in placental implantation: Relevance to early pregnancy loss.
- Prognostic value of humbug gene overexpression in stage II colon cancer.
- Loss of Raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells.
- Acute and chronic alcohol abuse modulate immunity.
- Lack of UCP2 reduces Fas-mediated liver injury in ob/ob mice and reveals importance of cell-specific UCP2 expression.
- Aspartyl-asparagyl beta hydroxylase over-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms.
- Signal transduction cascades and hepatitis B and C related hepatocellular carcinoma.
- DNA-based immunization breaks tolerance in a hepatitis C virus transgenic mouse model.
- Vaccination with protein-transduced dendritic cells elicits a sustained response to hepatitis C viral antigens.
- Wnt/Frizzled signaling in hepatocellular carcinoma.
- Hepatitis C virus core protein stimulates hepatocyte growth: correlation with upregulation of wnt-1 expression.
- Type 1 interferon augments DNA-based vaccination against hepatitis C virus core protein.
- Antibody-directed therapy for human hepatocellular carcinoma.
- Prevention of hepatocellular carcinoma.
- Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma.
- Expression of uncoupling protein-2 in human colon cancer.
- The human cervical cancer oncogene protein is a biomarker for human hepatocellular carcinoma.
- Modulation of hepatitis B virus secretion by naturally occurring mutations in the S gene.
- Glycine decarboxylase mediates a postbinding step in duck hepatitis B virus infection.
- Uncoupling protein-2 deficiency promotes oxidant stress and delays liver regeneration in mice.
- Resistance of HBV to adefovir dipivoxil: a case for combination antiviral therapy?
- Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liver.
- Insulin signaling through insulin receptor substrate 1 and 2 in normal liver development.
- Involvement of the p38 mitogen-activated protein kinase cascade in hepatocellular carcinoma.
- Human WISP1v, a member of the CCN family, is associated with invasive cholangiocarcinoma.
- Mechanisms of alcohol-induced tissue injury.
- Hepatitis C virus NS2 protein inhibits gene expression from different cellular and viral promoters in hepatic and nonhepatic cell lines.
- Role of the aspartyl-asparaginyl-beta-hydroxylase gene in neuroblastoma cell motility.
- Human aspartyl (asparaginyl) beta-hydroxylase monoclonal antibodies: potential biomarkers for pancreatic carcinoma.
- ATP luminescence-based motility-invasion assay.
- The AD7c-ntp neuronal thread protein biomarker for detecting Alzheimer's disease.
- Tie2 vascular endothelial receptor expression and function in hepatocellular carcinoma.
- Oncogenic signal transduction and therapeutic strategy for hepatocellular carcinoma.
- Cerebrovascular Pathology Contributes to the Heterogeneity of Alzheimer's Disease.
- X-ray Scatter Imaging of Hepatocellular Carcinoma in a Mouse Model Using Nanoparticle Contrast Agents.
Schools
University of Washington
Doctors Specialties
- Internal Medicine
- Gastroenterology
Accepted Insurances
Education
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Massachusetts General Hospital -
Johns Hopkins Bayview Medical Center -
Johns Hopkins University -
University of Washington School of Medicine
Hospital
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Rhode Island Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1689614703 |
| Last Name Of The Provider | WANDS |
| First Name Of The Provider | JACK |
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