Professor of Neurology, UC Irvine
Neurology
Dr. Ira T. Lott, MD
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Doctor Ira T. Lott, MD practices Neurology. He studied medicine at The Ohio State University College of Medicine. He received awards:"America's Top Doctors", "Top Doctors:LA Area", "Top Doctors:San Diego Area", "Top Doctors:Southern California", "Super Doctor" and "Fellow (FAAP)". Ira T. Lott is a published physician. He published 89 publications, including: 'Delayed-onset profound biotinidase deficiency.'
Publications
- Rapid assessment of cognitive function in down Syndrome across intellectual level and dementia status.
- Down Syndrome and Alzheimer's disease: Common pathways, common goals.
- Synaptophysin and Synaptojanin-1 in Down Syndrome are Differentially Affected by Alzheimer's Disease.
- Self-concept in children with Down Syndrome.
- The relationship between living arrangement and adherence to antiepileptic medications among individuals with developmental disabilities.
- Down Syndrome and Dementia: Seizures and Cognitive Decline.
- Antioxidants in Down Syndrome.
- Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down Syndrome.
- Down Syndrome and dementia: A randomized, controlled trial of antioxidant supplementation.
- Down Syndrome: from understanding the neurobiology to therapy.
- The genetic architecture of Down Syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies.
- Alzheimer's disease in Down Syndrome: neurobiology and risk.
- Toward a research agenda for Down Syndrome.
- Telemedicine, dementia and Down Syndrome: implications for Alzheimer disease.
- Alzheimer disease and Down Syndrome: factors in pathogenesis.
- Down Syndrome and Alzheimer disease: response to donepezil.
- Neuroimaging of individuals with Down's Syndrome at-risk for dementia: evidence for possible compensatory events.
- Possible compensatory events in adult Down Syndrome brain prior to the development of Alzheimer disease neuropathology: targets for nonpharmacological intervention.
- Rapid assessment of severe cognitive impairment in individuals with developmental disabilities.
- Temporal cortex hypermetabolism in Down Syndrome prior to the onset of dementia.
- Parallel compensatory and pathological events associated with tau pathology in middle aged individuals with Down Syndrome.
- Beta-amyloid deposition and neurofibrillary tangle association with caspase activation in Down Syndrome.
- Alpha- and beta-secretase activity as a function of age and beta-amyloid in Down Syndrome and normal brain.
- Longitudinal prescribing patterns for psychoactive medications in community-based individuals with developmental disabilities: utilization of pharmacy records.
- Neurological changes and emotional functioning in adults with Down Syndrome.
- Oxidation of Abeta and plaque biogenesis in Alzheimer's disease and Down Syndrome.
- Down Syndrome and Alzheimer's disease: a link between development and aging.
- Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome.
- Molecular dating of senile plaques in the brains of individuals with Down Syndrome and in aged dogs.
- Delayed-onset profound biotinidase deficiency.
- Premature aging in persons with Down Syndrome: MR findings.
- Magnetic resonance imaging of the aging brain in Down Syndrome.
- Cerebral metabolic change after treatment in biotinidase deficiency.
- The neurology of Alzheimer disease in Down Syndrome.
- The pathogenesis and treatment of copper deficiency in steely-hair Syndrome.
- Copper metabolism in the steely-hair Syndrome.
- The cellular pathology of neuronal ceroid-lipofuscinosis. A golgi-electronmicroscopic study.
- Sulfatide excretion in metachromatic leukodystrophy.
- The cellular pathology of Menkes steely hair Syndrome.
- Vitamin B6-dependent seizures: pathology and chemical findings in brain.
- Abnormal copper metabolism in Menke''s steely-hair Syndrome.
- Familial amentia, unusual ventricular calcifications, and increased cerebrospinal fluid protein.
- Mannosidosis. New clinical presentation, enzyme studied, and carbohydrate analysis.
- Apparent biochemical homozygosity in two obligatory heterozygotes for metachromatic leukodystrophy.
- Biosynthesis and release of glycoproteins by pineal gland in organ culture.
- Dietary treatment of an infant with isovaleric acidemia.
- Down''s Syndrome: transport, storage, and metabolism of serotonin in blood platelets.
- Down''s Syndrome. Central monoamine turnover in patients with diminished platelet serotonin.
- Isovaleric acidemia: results of family study and dietary treatment.
- Urinary noradrenaline and playroom behaviour in hyperactive boys.
- Plasticity of hippocampal circuitry in Alzheimer's disease.
- Long-term follow-up of infants and children treated with extracorporeal membrane oxygenation (ECMO): a preliminary report.
- Liver in the cerebro-hepato-renal Syndrome: defective bile acid synthesis and abnormal mitochondria.
- A light and electron microscopic study of mannosidosis.
- Response-contingent taste-aversion in treating chronic ruminative vomiting of institutionalised profoundly retarded children.
- Mannosidosis: isolation and comparison of mannose-containing oligosaccharides from gingiva and urine.
- Serum and urinary trisaccharides in mannosidosis.
- Pancytopenia in mannosidosis.
- Neuropathological findings and the biology of neurofibromatosis.
- Communicating hydrocephalus and lysosomal inclusions in mannosidosis.
- Fetal hydrocephalus and ear anomalies associated with maternal use of isotretinoin.
- Down's Syndrome, aging, and Alzheimer's disease: a clinical review.
- Dementia in Down's Syndrome: observations from a neurology clinic.
- Neuroaxonal dystrophy and Down's Syndrome. Report of a case.
- Speech and histidinemia: methodology and evaluation of four cases.
- Density and distribution of NMDA receptors in the human hippocampus in Alzheimer''s disease.
- MR imaging of cavitary lesions in the brain with Hurler/Scheie.
- Cerebral cortical contributions to sensory evoked potentials: hydranencephaly.
- Long-term neurophysiologic outcome after neonatal extracorporeal membrane oxygenation.
- Retinoic acid embryopathy.
- Cortical CSF volume fluctuations by MRI in brain aging, dementia and hydrocephalus.
- A fibril-specific, conformation-dependent antibody recognizes a subset of Abeta plaques in Alzheimer disease, Down Syndrome and Tg2576 transgenic mouse brain.
- Detection of Alzheimer disease in individuals with Down Syndrome.
- Myoclonic encephalopathy of infants.
- Olfactory classical conditioning in neonates.
- Regional Cerebral glucose metabolism and attention in adults with a history of childhood autism.
- Playroom observations of hyperactive children on medication.
- Traumatic asphyxiation caused by a motorized parking gate.
- Effects of isotretinoin on the behavior of neural crest cells in vitro.
- Magnetic resonance imaging analysis of age-related changes in the brains of individuals with Down's Syndrome.
- Down Syndrome and beta-amyloid deposition.
- Learning and memory as a function of age in Down Syndrome: a study using animal-based tasks.
- Beta-amyloid, oxidative stress and down Syndrome.
- Cognitive deficits and associated neurological complications in individuals with Down''s Syndrome.
- Systemic mitochondrial dysfunction and the etiology of Alzheimer''s disease and down Syndrome dementia.
- Altered brain dynamics during voluntary movement in individuals with Down Syndrome.
- Plasma amyloid-β as a function of age, level of intellectual disability, and presence of dementia in Down Syndrome.
- Donepezil for treatment of cognitive dysfunction in children with Down Syndrome aged 10-17.
Schools
Ohio State University College of Medicine
Massachusetts General Hospital
National Institute Health
Procedures Preformed
- EEG (Electroencephalogram)
Conditions Treated
- Ataxia
- Cerebral Palsy
- Concussion
- Convulsions
- View All
Doctors Specialties
- Pediatric Neurology
- Pediatrics
- Neurology
Accepted Insurances
Awards
- America's Top Doctors
- Top Doctors:LA Area
- Top Doctors:San Diego Area
- Top Doctors:Southern California
- Super Doctor
- Fellow (FAAP)
Education
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Massachusetts General Hospital -
The Ohio State University College of Medicine
Hospital
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Hoag Memorial Hospital Presbyterian -
UC Irvine Medical Center -
Children's Hospital of Orange County
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