Associate Professor of Surgery, University Pittsburgh
General Surgery
Dr. Howard D. Edington, MD
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Howard D. Edington, MD practices General Surgery. He studied medicine at Temple University School of Medicine. He received awards:"America's Top Doctors", "America's Top Doctors for Cancer", "Pittsburgh Magazine" and "Top MD". Howard Edington is a published doctor as well. He has 55 publications published. The latest was: Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies. Howard Edington is registered with Medicare.
Publications
- Effects of high-dose IFNalpha2b on regional lymph node metastases of human melanoma: modulation of STAT5, FOXP3, and IL-17.
- STAT3 as a biomarker of progression in atypical nevi of patients with melanoma: dose-response effects of systemic IFNalpha therapy.
- Multiplex analysis of serum cytokines in melanoma patients treated with interferon-alpha2b.
- Modulation of signal transducers and activators of transcription 1 and 3 signaling in melanoma by high-dose IFNalpha2b.
- Controlled release of bioactive doxorubicin from microspheres embedded within gelatin scaffolds.
- Neoadjuvant treatment of regional stage IIIB melanoma with high-dose interferon alfa-2b induces objective tumor regression in association with modulation of tumor infi...
- Preemptive analgesia with bupivacaine for segmental mastectomy.
- Expression analysis of genes identified by molecular profiling of VGP melanomas and MGP melanoma-positive lymph nodes.
- Fluorescence imaging analysis of upstream regulators and downstream targets of STAT3 in melanoma precursor Lesions obtained from patients before and after systemic low...
- Immune monitoring of the circulation and the tumor microenvironment in patients with regionally advanced melanoma receiving neoadjuvant ipilimumab.
- Accumulation of low-avidity anti-melanocortin receptor 1 (anti-MC1R) CD8+ T cells in the lesional Skin of a patient with melanoma-related depigmentation.
- Laparoscopically harvested omental flap for chest wall and intrathoracic reconstruction.
- Sentinel lymph node biopsy for atypical melanocytic Lesions with spitzoid features.
- Thoracoscopic internal mammary sentinel node biopsy: an animal model of a new technique.
- Dendritic cells in Cancer immunotherapy: vaccines or autologous transplants?
- Helper activity of natural killer cells during the dendritic cell-mediated induction of melanoma-specific cytotoxic T cells.
- Lobular carcinoma in situ of the breast and ductoscopy.
- Pseudoangiomatous stromal hyperplasia (PASH) of the breast: intraductal appearance.
- Intraductal location of the sclerosing adenosis of the breast.
- Pharmacologic manipulation of postoperative labial wound contraction and midfacial growth in rabbits.
- Lymphatic mapping with isosulfan blue dye in squamous cell carcinoma of the head and neck.
- Gene therapy of malignant gliomas: a phase I study of IL-4-HSV-TK gene-modified autologous tumor to elicit an immune response.
- Gene therapy of malignant gliomas: a pilot study of vaccination with irradiated autologous glioma and dendritic cells admixed with IL-4 transduced fibroblasts to elici...
- Biologic therapy.
- Jejeunal variceal hemorrhage: an unusual complication of needle catheter jejeunostomy.
- Effects of intravenous versus intraatrial administration of doxorubicin on the function and structure of the heart.
- Thymic hyperplasia masquerading as recurrent Hodgkin's disease: case report and review of the literature.
- Postoperative abdominal wall defects with enterocutaneous fistulae.
- Peripheral nerve entrapment: an unusual adverse event with high-dose interleukin-2 therapy.
- Fascial release as an adjunct to wound closure.
- Organization and development of a university multidisciplinary wound care clinic.
- Gene therapy of Cancer: a pilot study of IL-4-gene-modified fibroblasts admixed with autologous tumor to elicit an immune response.
- Gene therapy and tissue engineering.
- Impaired wound healing and angiogenesis in eNOS-deficient mice.
- Systemic interferon-alpha (IFN-alpha) treatment leads to Stat3 inactivation in melanoma precursor Lesions.
- Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies.
- The effects of soft-tissue expansion on lip repair and midfacial growth in a rabbit cleft lip model.
- Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production.
- Preliminary report of a new treatment strategy for advanced pelvic malignancy: surgical resection and radiation therapy using afterloading catheters plus an inflatable...
- Prolonged Skin allograft survival through enhancement effects on donor tissue.
- Management of the surgically traumatized, irradiated, and infected pelvis.
- Radioimmunoimaging of metastatic medullary carcinoma of the thyroid gland using an indium-111-labeled monoclonal antibody to CEA.
- In vitro and in vivo models for monitoring the adoptive immunotherapeutic effects of recombinant gamma-interferon-activated human monocytes.
- V-Y closure for abdominal wall stomal reduction.
- Reconstruction of a functional hemidiaphragm with use of omentum and latissimus dorsi flaps.
- Analysis of therapeutic and immunologic effects of R(24) anti-GD3 monoclonal antibody in 37 patients with metastatic melanoma.
- Macroscopic spectral imaging and gene expression analysis of the early stages of melanoma.
- Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer.
- Molecular analysis of melanoma precursor Lesions.
- SAGE and antibody array analysis of melanoma-infiltrated lymph nodes: identification of Ubc9 as an important molecule in advanced-stage melanomas.
- Recurrence rate of diabetic neurotrophic foot ulcers healed using topical application of growth factors released from platelets.
- Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of recurrent glioblastoma: preliminary observations in a patien...
- Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomas.
- Impact of IFNalpha2b upon pSTAT3 and the MEK/ERK MAPK pathway in melanoma.
Schools
Temple Univ Sch Of Med
Procedures Preformed
- Adjacent Tissue Transfer
- Breast Reconstruction
- Dressing and-or Debridement of Wound, Infection, or Burn (incl. Negative Pressure Wound Therapy)
- Excision of Benign Skin Lesion
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Conditions Treated
- Benign Skin Lesion
- Hidradenitis
- Osteoarthritis
- Rheumatoid Arthritis
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Doctors Specialties
- Orthopedic Hand Surgery
- Surgical Oncology
- General Surgery
Accepted Insurances
Awards
- America's Top Doctors
- America's Top Doctors for Cancer
- Pittsburgh Magazine
- Top MD
Education
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University of Pittsburgh Medical Center -
Temple University School of Medicine
Drug Facts
| NPI NUMBER | 1568435592 | |
| NPPES Provider LastName | EDINGTON | |
| NPPES Provider FirstName | HOWARD | |
| NPPES Provider ZIPCode | 152133108 | |
| NPPES Provider State | PA | |
| Specialty Description | Surgical Oncology | |
| Total Claim Count | 213.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 24.0 | |
| Percent Opioid Claims | 11.27 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1568435592 |
| Last Name Of The Provider | EDINGTON |
| First Name Of The Provider | HOWARD |
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