Professor of Orthopedic Surgery, University Wash

Orthopaedic Surgery

Dr. Howard A. Chansky practices Orthopaedic Surgery. He went to medical school at Perelman School of Medicine at the University of Pennsylvania. He over the years received 3 awards: "Regional Top Doctor", "Top MD" and "Super Doctor". Dr. Howard A. Chansky is a published doctor and has 36 publications published. The lastest was: 'Expression of cartilage extracellular matrix and potential regulatory genes in a new human chondrosarcoma cell line.'

Publications

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• Prolonged Opioid Use After Knee Arthroscopy in Military Veterans.
• ESET histone methyltransferase regulates osteoblastic differentiation of mesenchymal stem cells during postnatal bone development.
• Mesenchymal-specific knockout of ESET histone methyltransferase causes ectopic hypertrophy and terminal differentiation of articular chondrocytes.
• Salvage of an Infected Periprosthetic Failed Fracture Fixation in a Nonagenarian.
• ESET histone methyltransferase is essential to hypertrophic differentiation of growth plate chondrocytes and formation of epiphyseal plates.
• FOXO1 is a direct target of EWS-Fli1 oncogenic fusion protein in Ewing's sarcoma cells.
• EWS/FLI1 suppresses retinoblastoma protein function and senescence in Ewing's sarcoma cells.
• TLS-ERG leukemia fusion protein deregulates cyclin-dependent kinase 1 and blocks terminal differentiation of myeloid progenitor cells.
• Rab23 regulates differentiation of ATDC5 chondroprogenitor cells.
• TASR-1 regulates alternative splicing of collagen genes in chondrogenic cells.
• The oncogenic TLS-ERG fusion protein exerts different effects in hematopoietic cells and fibroblasts.
• Articular cartilage adjacent to experimental defects is subject to atypical strains.
• Targeting of EWS/FLI-1 by RNA interference attenuates the tumor phenotype of Ewing's sarcoma cells in vitro.
• Survival motor neuron (SMN) protein interacts with transcription corepressor mSin3A.
• Toward better interaction between orthopaedists and researchers.
• Testosterone administration to men increases hepatic lipase activity and decreases HDL and LDL size in 3 wk.
• COL11A2 collagen gene transcription is differentially regulated by EWS/ERG sarcoma fusion protein and wild-type ERG.
• Preoperative supraphysiological testosterone in older men undergoing Knee replacement surgery.
• RNA splicing mediated by YB-1 is inhibited by TLS/CHOP in human myxoid liposarcoma cells.
• Comparison of open and arthroscopic subacromial decompression.
• Genomic structure and expression of the mouse ESET gene encoding an ERG-associated histone methyltransferase with a SET domain.
• An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B.
• Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor.
• Characterization and expression of the human gene encoding two translocation liposarcoma protein-associated serine-arginine (TASR) proteins.
• Proper expression of helix-loop-helix protein Id2 is important to chondrogenic differentiation of ATDC5 cells.
• The vascularity of the rotator cuff.
• Effect of sterilization and storage treatments on screw pullout strength in human allograft bone.
• Pediatric soft-tissue sarcomas.
• Evidence for a polyclonal etiology of palmar fibromatosis.
• Irreducible posterolateral dislocation of the Knee.
• EWS.Fli-1 fusion protein interacts with hyperphosphorylated RNA polymerase II and interferes with serine-arginine protein-mediated RNA splicing.
• Oncogenic TLS/ERG and EWS/Fli-1 fusion proteins inhibit RNA splicing mediated by YB-1 protein.
• Expression of cartilage extracellular matrix and potential regulatory genes in a new human chondrosarcoma cell line.
• Loss of heterozygosity in chondrosarcomas for markers linked to hereditary multiple exostoses loci on chromosomes 8 and 11.
• The development of a telemedical cancer center within the Veterans Affairs Health Care System: a report of preliminary clinical results.

Schools

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• University Of Pennsylvania School Of Medicine

• University Of Pennsylvania

• University of Washington

Procedures Preformed

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• All Shoulder or Elbow Replacement Procedures
• Dressing and-or Debridement of Wound, Infection, or Burn (incl. Negative Pressure Wound Therapy)
• Elbow Fracture and-or Dislocation Treatment, Closed
• Epidural Block, Facet Blocks
• View All

Conditions Treated

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• Ankle Fracture
• Ankylosing Spondylitis
• Arm Fracture (incl. Elbow and Shoulder)
• Back Pain
• View All

Doctors Specialties

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• Orthopedic Surgery
• Orthopaedic Surgery

Accepted Insurances

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Awards

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• Regional Top Doctor
• Top MD
• Super Doctor

Education

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• University of Pennsylvania Health System
• Perelman School of Medicine at the University of Pennsylvania

Hospital

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• UW Medicine/Harborview Medical Center
• University of Washington Medical Center

Helpful Reviews

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Medicare Facts

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National Provider Identifier [NPI]	1780768291
Last Name Of The Provider	CHANSKY
First Name Of The Provider	HOWARD
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