Physician
Infectious Disease
Dr. Helene F. Rosenberg, MD
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Dr. Helene F. Rosenberg works in the field of Infectious Disease. Dr. Helene F. Rosenberg is a published MD. She has 99 papers published. The most current publication "Immortalized MH-S cells lack defining features of primary alveolar macrophages and do not support mouse pneumovirus replication."
Publications
- Immortalized MH-S cells lack defining features of primary alveolar macrophages and do not support mouse pneumovirus replication.
- Priming of the Respiratory Tract with Immunobiotic Lactobacillus plantarum Limits Infection of Alveolar Macrophages with Recombinant Pneumonia Virus of Mice (rK2-PVM).
- Sustained inflammation and differential expression of interferons type I and III in PVM-infected interferon-gamma (IFNγ) gene-deleted mice.
- Respiratory viral infection, epithelial cytokines, and innate lymphoid cells in asthma exacerbations.
- B Cells Are Not Essential for Lactobacillus-Mediated Protection against Lethal Pneumovirus Infection.
- Activated mouse eosinophils protect against lethal respiratory virus infection.
- Reply to Eosinophil cytolysis and release of cell-free granules.
- Novel pneumoviruses (PnVs): Evolution and inflammatory pathology.
- Expression of the secondary granule proteins major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX) is required for eosinophilopoiesis in mice.
- Editorial: Mouse eosinophils expressing Cre recombinase: endless "flox"ibilities.
- Novel Inflammatory Markers, Clinical Risk Factors, and Virus Type Associated with Severe Respiratory Syncytial Virus Infection.
- Chemotaxis of bone marrow-derived eosinophils in vivo: A novel method to explore receptor-dependent trafficking in the mouse.
- Lactobacillus priming of the respiratory tract: Heterologous immunity and protection against lethal pneumovirus infection.
- Nasopharyngeal detection of respiratory viruses in febrile neutropenic children.
- The Pneumonia Virus of Mice (PVM) model of acute respiratory infection.
- Eosinophils: changing perspectives in health and disease.
- Inflammatory Responses to Respiratory Syncytial Virus (RSV) Infection and the Development of Immunomodulatory Pharmacotherapeutics.
- Depletion of alveolar macrophages prolongs survival in response to acute pneumovirus infection.
- Defective eosinophil hematopoiesis ex vivo in inbred Rocky Mountain White (IRW) mice.
- Canine pneumovirus replicates in mouse lung tissue and elicits inflammatory pathology.
- Viral etiology of acute febrile respiratory illnesses in hospitalized children younger than 24 months.
- Plasmacytoid Dendritic Cells Promote Host Defense against Acute Pneumovirus Infection via the TLR7-MyD88-Dependent Signaling Pathway.
- Animal models of human respiratory syncytial virus disease.
- Antigen profiles for the quantitative assessment of eosinophils in mouse tissues by flow cytometry.
- Lactobacillus-mediated priming of the respiratory mucosa protects against lethal pneumovirus infection.
- Eosinophils are in the swim!
- Mouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel rece...
- Local production of inflammatory mediators during childhood parainfluenza virus infection.
- Granzyme A- and B-cluster deficiency delays acute lung injury in pneumovirus-infected mice.
- RNase 1 genes from the family Sciuridae define a novel rodent ribonuclease cluster.
- Pneumoviruses infect eosinophils and elicit MyD88-dependent release of chemoattractant cytokines and interleukin-6.
- Pulmonary eosinophils and their role in immunopathologic responses to formalin-inactivated pneumonia virus of mice.
- GATA transcription factors regulate the expression of the human eosinophil-derived neurotoxin (RNase 2) gene.
- Multisystemic eosinophilia resembling hypereosinophilic syndrome in a colony-bred owl monkey (Aotus vociferans).
- Generation of eosinophils from unselected bone marrow progenitors: wild-type, TLR- and eosinophil-deficient mice.
- Eosinophils and their interactions with respiratory virus pathogens.
- Mechanical ventilation enhances lung inflammation and caspase activity in a model of mouse pneumovirus infection.
- The 2008 Dolph Adams award and the state of the journal of leukocyte biology.
- HMGB1, a novel biomarker of inflammatory demyelinating disease: an interview with Dr. Robert A. Harris.
- Functionally competent eosinophils differentiated ex vivo in high purity from normal mouse bone marrow.
- Eosinophils unleashed.
- Cytokines and fibrocyte differentiation -- altering the balance: an interview with Dr. Darrell Pilling. Interview by Helene F. Rosenberg.
- RNase A ribonucleases and host defense: an evolving story.
- The 2007 Dolph Adams Award and the state of the Journal of Leukocyte Biology.
- Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses.
- Diminished inflammatory responses to natural pneumovirus infection among older mice.
- Eosinophils contribute to innate antiviral immunity and promote clearance of respiratory syncytial virus.
- Eosinophils from lineage-ablated Delta dblGATA bone marrow progenitors: the dblGATA enhancer in the promoter of GATA-1 is not essential for differentiation ex vivo.
- Eosinophil trafficking in allergy and asthma.
- Toll-like receptors, endogenous ligands, and constitutive control (or, why I'm still standing at the podium): an interview with Dr. Jeffrey L. Platt.
- Schistosoma mansoni infection in eosinophil lineage-ablated mice.
- Evolution and function of leukocyte RNase A ribonucleases of the avian species, Gallus gallus.
- Interview with Dr. Francisco Sanchez-Madrid regarding Pivotal Advance: CD69 targeting differentially affects the course of collagen-induced arthritis.
- Respiratory dysfunction and proinflammatory chemokines in the pneumonia virus of mice (PVM) model of viral bronchiolitis.
- Interleukin-5 (IL-5) augments the progression of liver fibrosis by regulating IL-13 activity.
- Proteomic-based discovery and characterization of glycosylated eosinophil-derived neurotoxin and COOH-terminal osteopontin fragments for ovarian cancer in urine.
- Inflammatory responses to pneumovirus infection in IFN-alpha beta R gene-deleted mice.
- Advances in the treatment and prevention of severe viral bronchiolitis.
- Human ribonuclease A superfamily members, eosinophil-derived neurotoxin and pancreatic ribonuclease, induce dendritic cell maturation and activation.
- Animal models for studying respiratory syncytial virus infection and its long term effects on lung function.
- Isolation, characterization, and evolutionary divergence of mouse RNase 6: evidence for unusual evolution in rodents.
- Plasminogen activator inhibitor-2 (PAI-2) in eosinophilic leukocytes.
- Functional antagonism of chemokine receptor CCR1 reduces mortality in acute pneumovirus infection in vivo.
- Animal pneumoviruses: molecular genetics and pathogenesis.
- Gene microarray analysis reveals interleukin-5-dependent transcriptional targets in mouse bone marrow.
- Identification of a purine-rich intronic enhancer element in the mouse eosinophil-associated ribonuclease 2 (mEar 2) gene.
- Chemokine regulation of inflammation during acute viral infection.
- Eosinophil-derived neurotoxin (EDN), an antimicrobial protein with chemotactic activities for dendritic cells.
- Both aromatic and cationic residues contribute to the membrane-lytic and bactericidal activity of eosinophil cationic protein.
- Localized eosinophil degranulation mediates disease in tropical pulmonary eosinophilia.
- Altered pathogenesis of severe pneumovirus infection in response to combined antiviral and specific immunomodulatory agents.
- Replication of respiratory syncytial virus is inhibited in target cells generating nitric oxide in situ.
- De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new me...
- Differential expression of proinflammatory cytokine genes in vivo in response to pathogenic and nonpathogenic pneumovirus infections.
- Pulmonary eosinophilia in mice devoid of interleukin-5.
- Complementary advantageous substitutions in the evolution of an antiviral RNase of higher primates.
- Diversifying selection of the tumor-growth promoter angiogenin in primate evolution.
- Adaptive evolution of a duplicated pancreatic ribonuclease gene in a leaf-eating monkey.
- Physiologic Concentrations of HMGB1 Have No Impact on Cytokine-Mediated Eosinophil Survival or Chemotaxis in Response to Eotaxin-2 (CCL24).
- Eosinophils and Respiratory Virus Infection: A Dual-Standard Curve qRT-PCR-Based Method for Determining Virus Recovery from Mouse Lung Tissue.
- Early-life viral infection and allergen exposure interact to induce an asthmatic phenotype in mice.
- Inflammatory responses to acute pneumovirus infection in neonatal mice.
- Isolation of human eosinophils: microbead method has no impact on IL-5 sustained viability.
- Interferon-gamma coordinates CCL3-mediated neutrophil recruitment in vivo.
- Respiratory viruses and eosinophils: exploring the connections.
- Targeting eosinophils in asthma.
- Pneumonia virus of mice: severe respiratory infection in a natural host.
- Ribavirin and cysteinyl leukotriene-1 receptor blockade as treatment for severe bronchiolitis.
- Eosinophils: biological properties and role in health and disease.
- Efficient replication of pneumonia virus of mice (PVM) in a mouse macrophage cell line.
- The RNase a superfamily: generation of diversity and innate host defense.
- Mucosal inoculation with an attenuated mouse pneumovirus strain protects against virulent challenge in wild type and interferon-gamma receptor deficient mice.
- Interleukin-5 does not influence differential transcription of transmembrane and soluble isoforms of IL-5R alpha in vivo.
- The mouse RNase 4 and RNase 5/ang 1 locus utilizes dual promoters for tissue-specific expression.
- Characterization of a ribonuclease gene and encoded protein from the reptile, Iguana iguana.
- Surface-exposed amino acids of eosinophil cationic protein play a critical role in the inhibition of mammalian cell proliferation.
- The pneumonia virus of mice infection model for severe respiratory syncytial virus infection: identifying novel targets for therapeutic intervention.
- RNase 8, a novel RNase A superfamily ribonuclease expressed uniquely in placenta.
Schools
Weill Cornell Medical College
Doctors Specialties
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
Education
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Beth Israel Deaconess Medical Center -
Boston University Medical Center
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