Physician
Pulmonology
Dr. Guy A. Zimmerman, MD
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Zimmerman practices Pulmonology. He graduated from Baylor College of Medicine. He received awards:"Elected Member" and "Whos Who in Medicine and Healthcare". Guy A. Zimmerman is a published doctor and has 91 publications published. The lastest was: 'Integrin D2 (CD11d/CD18) Is Expressed by Human Circulating and Tissue Myeloid Leukocytes and Mediates Inflammatory Signaling.'
Publications
- Unraveling the PAF-AH/Lp-PLA2 controversy.
- Platelet Activation and Apoptosis Modulate Monocyte Inflammatory Responses in Dengue.
- Platelet-Monocyte Aggregate Formation and Mortality Risk in Older Patients With Severe Sepsis and Septic Shock.
- Reply to Schattner.
- Germline Mutations in NFKB2 Implicate the Noncanonical NF-κB Pathway in the Pathogenesis of Common Variable Immunodeficiency.
- Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation.
- Platelets as cellular effectors of inflammation in vascular diseases.
- Dengue Induces Platelet Activation, Mitochondrial Dysfunction and Cell Death through Mechanisms that Involve DC-SIGN and Caspases.
- Methicillin-resistant Staphylococcus aureus - induced thrombo-inflammatory response is reduced with timely antibiotic administration.
- Translational control of JunB, an AP-1 transcription factor, in activated human endothelial cells.
- Bacterial clearance in septic mice is modulated by MCP-1/CCL2 and nitric oxide.
- Lessons from rare maladies: leukocyte adhesion deficiency syndromes.
- Statins decrease neuroinflammation and prevent cognitive impairment after cerebral malaria.
- 18F-FDG PET in the Evaluation of Acuity of Deep Vein Thrombosis.
- Bacteria differentially induce degradation of Bcl xL, a survival protein, by human platelets.
- Platelets in Lung Biology.
- In Vivo Platelet Activation in Critically Ill Patients With Primary 2009 Influenza A(H1N1).
- Whole blood flow cytometry measurements of in vivo platelet activation in critically-Ill patients are influenced by variability in blood sampling techniques.
- Leukocyte adhesion deficiency-I variant syndrome (LAD-Iv, LAD-III): Molecular characterization of the defect in an index family.
- Novel Anti-bacterial Activities of ?-defensin 1 in Human Platelets: Suppression of Pathogen Growth and Signaling of Neutrophil Extracellular Trap Formation.
- Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum.
- A pilot study utilizing whole body 18 F-FDG-PET/CT as a comprehensive screening strategy for occult malignancy in patients with unprovoked venous thromboembolism.
- Genome wide RNA-seq analysis of human and mouse platelet transcriptomes.
- Anucleate platelets generate progeny.
- Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza.
- Immunology. Arsonists in rheumatoid arthritis.
- Cognitive dysfunction is sustained after rescue therapy in experimental cerebral malaria, and is reduced by additive antioxidant therapy.
- Thinking small, but with big league consequences: procoagulant microparticles in the alveolar space.
- Fibrinogen selects selectins.
- PAF-acetylhydrolase expressed during megakaryocyte differentiation inactivates PAF-like lipids.
- Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates.
- LAD syndromes: FERMT3 kindles the signal.
- Comparative genomics: fishing nets hemostatic catch.
- Amicus or adversary: platelets in lung biology, acute injury, and inflammation.
- A yeast PAF acetylhydrolase ortholog suppresses oxidative death.
- Promises, promises: N-terminal proB-type natriuretic peptide as a biomarker in acute lung injury.
- Hypoxic erythrocytes spark lung leukocyte adhesion.
- Signal-dependent protein synthesis by activated platelets: new pathways to altered phenotype and function.
- Integrin alphaDbeta2 is dynamically expressed by inflamed macrophages and alters the natural history of lethal systemic infections.
- Translational control in endothelial cells.
- mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets.
- Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets.
- Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling.
- Exogenous platelet-activating factor acetylhydrolase reduces mortality in mice with systemic inflammatory response syndrome and sepsis.
- New roles for an old drug: inhibition of gene expression by dipyridamole in platelet-leukocyte aggregates.
- Ultraviolet B radiation generates platelet-activating factor-like phospholipids underlying cutaneous damage.
- Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management.
- Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets.
- Plasma platelet-activating factor acetylhydrolase is a dynamic variable in critical illness: In the end, is change good for you?
- Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates.
- Signaling to translational control pathways: diversity in gene regulation in inflammatory and vascular cells.
- Endothelial cell confluence regulates cyclooxygenase-2 and prostaglandin E2 production that modulate motility.
- Activated polymorphonuclear leukocytes rapidly synthesize retinoic acid receptor-alpha: a mechanism for translational control of transcriptional events.
- The p38 MAPK pathway mediates transcriptional activation of the plasma platelet-activating factor acetylhydrolase gene in macrophages stimulated with lipopolysaccharide.
- Change in protein phenotype without a nucleus: translational control in platelets.
- Neutrophils alter the inflammatory milieu by signal-dependent translation of constitutive messenger RNAs.
- Endotoxin contamination of ovalbumin suppresses murine immunologic responses and development of airway hyper-reactivity.
- Endotoxins stimulate neutrophil adhesion followed by synthesis and release of platelet-activating factor in microparticles.
- Evaluating the relevance of the platelet transcriptome.
- Synergism between platelet-activating factor-like phospholipids and peroxisome proliferator-activated receptor gamma agonists generated during low density lipoprotein ...
- Regulation of cyclooxygenase-2 expression by the translational silencer TIA-1.
- Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group.
- Cell-cell interactions: leukocyte-endothelial interactions.
- Platelet-activating factor acetylhydrolase is increased in lung lavage fluid from patients with acute respiratory distress syndrome.
- Platelet-activating factor acetylhydrolase, and not paraoxonase-1, is the oxidized phospholipid hydrolase of high density lipoprotein particles.
- Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist.
- Fluid flow regulates E-selectin protein levels in human endothelial cells by inhibiting translation.
- Platelet-activating factor, a pleiotrophic mediator of physiological and pathological processes.
- Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome.
- Platelets, endothelial cells, inflammatory chemokines, and restenosis: complex signaling in the vascular play book.
- Temporal correlation of measurements of airway hyperresponsiveness in ovalbumin-sensitized mice.
- Outside-in signals delivered by matrix metalloproteinase-1 regulate platelet function.
- The platelet-activating factor signaling system and its regulators in syndromes of inflammation and thrombosis.
- Sol Sherry lecture in thrombosis: molecular events in acute inflammation.
- Monocyte chemoattractant protein-1 and 5-lipoxygenase products recruit leukocytes in response to platelet-activating factor-like lipids in oxidized low-density lipopro...
- Cyclooxygenase-2 is induced in monocytes by peroxisome proliferator activated receptor gamma and oxidized alkyl phospholipids from oxidized low density lipoprotein.
- Activation of vascular cells by PAF-like lipids in oxidized LDL.
- Retinoic acid-inducible gene-I is induced in endothelial cells by LPS and regulates expression of COX-2.
- Ceramide generation in situ alters leukocyte cytoskeletal organization and beta 2-integrin function and causes complete degranulation.
- Leukocyte adhesion deficiency syndromes: adhesion and tethering defects involving beta 2 integrins and selectin ligands.
- Integrin αDβ2 (CD11d/CD18) Is Expressed by Human Circulating and Tissue Myeloid Leukocytes and Mediates Inflammatory Signaling.
- Bacterial Clearance Is Improved in Septic Mice by Platelet-Activating Factor-Acetylhydrolase (PAF-AH) Administration.
- Molecular characterization of the constitutive expression of the plasma platelet-activating factor acetylhydrolase gene in macrophages.
- PAF, ceramide and pulmonary edema: alveolar flooding and a flood of questions.
- Regulating inflammation through the anti-inflammatory enzyme platelet-activating factor-acetylhydrolase.
- Intramural delivery of Sirolimus prevents vascular remodeling following balloon injury.
- Lung production of platelet-activating factor acetylhydrolase in oleic acid-induced acute lung injury.
- The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses.
- Platelets: signaling cells in the immune continuum.
- Persistent cognitive impairment after cerebral malaria: models, mechanisms and adjunctive therapies.
Schools
Baylor University
Vanderbilt University
Jackson Memorial Hospital
University Of Pennsylvania
Doctors Specialties
- Pulmonology
Accepted Insurances
Awards
- Elected Member
- Whos Who in Medicine and Healthcare
Education
-
University of Washington -
University of Utah -
Baylor College of Medicine
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