Assistant Professor, Medicine, Perelman School of Medicine

Hematology

Dr. Gregory L. Beatty, MD

Doctor Gregory L. Beatty, MD works in the field of Hematology. He graduated from Perelman School of Medicine at the University of Pennsylvania. Gregory Beatty is also a published doctor. He has 22 paper published. The most recent paper is: IFN-gamma and CCL2 cooperate to redirect tumor-infiltrating monocytes to degrade fibrosis and enhance chemotherapy efficacy in pancreatic carcinoma.

Publications

IFN-gamma and CCL2 cooperate to redirect tumor-infiltrating monocytes to degrade fibrosis and enhance chemotherapy efficacy in Pancreatic carcinoma.
Immune escape mechanisms as a guide for Cancer immunotherapy.
Mesothelin-specific Chimeric Antigen Receptor mRNA-Engineered T cells Induce Anti-Tumor Activity in Solid Malignancies.
Harnessing the antitumor potential of macrophages for Cancer immunotherapy.
Macrophage-based immunotherapy for the treatment of Pancreatic ductal adenocarcinoma.
A phase I study of an agonist CD40 monoclonal antibody (CP-870,893) in combination with gemcitabine in patients with advanced Pancreatic ductal adenocarcinoma.
T cells expressing chimeric antigen receptors can cause anaphylaxis in humans.
CD40 immunotherapy for pancreatic Cancer.
Regulation of tumor growth by IFN-gamma in Cancer immunotherapy.
IFN-gamma-dependent inhibition of tumor angiogenesis by tumor-infiltrating CD4+ T cells requires tumor responsiveness to IFN-gamma.
IFN-gamma can promote tumor evasion of the immune system in vivo by down-regulating cellular levels of an endogenous tumor antigen.
EMT and Dissemination Precede Pancreatic Tumor Formation.
CD40 agonists alter tumor stroma and show efficacy against Pancreatic carcinoma in mice and humans.
Functional unresponsiveness and replicative senescence of myeloid Leukemia antigen-specific CD8+ T cells after allogeneic stem cell transplantation.
Collapse of the CD27+ B-cell compartment associated with systemic plasmacytosis in patients with advanced melanoma and other Cancers.
Immunosurveillance of pancreatic adenocarcinoma: insights from genetically engineered mouse models of Cancer.
Telomerase as a universal tumor antigen for Cancer vaccines.
Bevacizumab and oxaliplatin-based chemotherapy in metastatic colorectal Cancer.
Telomerase-specific T-cell immunity in breast Cancer: effect of vaccination on tumor immunosurveillance.
Phase I clinical trial of costimulated, IL-4 polarized donor CD4+ T cells as augmentation of allogeneic hematopoietic cell transplantation.
Tumor sensitivity to IFN-gamma is required for successful antigen-specific immunotherapy of a transplantable mouse tumor model for HPV-transformed tumors.

Schools

Perelman School of Medicine University of Pennsylvania

Conditions Treated

Acute Leukemia
Liver Cancer
Myeloproliferative Disorders
Pancreatic Cancer
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Doctors Specialties

Medical Oncology
Oncology
Hematology

Accepted Insurances

Education

University of Pennsylvania Health System
Perelman School of Medicine at the University of Pennsylvania

Hospital

Philadelphia Veterans Affairs Medical Center
Hospital of the University of Pennsylvania

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