Physician
Pathology
Dr. Gregory G. Freund, MD
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Gregory Freund is an expert in the field of Pathology. He attended University of Rochester School of Medicine and Dentistry. Gregory Freund is a published doctor and has 100 publications published. The lastest was: 'Phosphatidylinositol 3''-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase.' He is registered with Medicare and accepts Medicare payments.
Publications
- IL-4 Knock Out Mice Display Anxiety-Like Behavior.
- Effect of Obesity on Acute Hemostatic Responses to Live-Fire Training Drills.
- Modulation of neuroimmunity by adenosine and its receptors: Metabolism to mental illness.
- The saturated fatty acid, palmitic acid, induces anxiety-like behavior in mice.
- Adenosine through the A2A adenosine receptor increases IL-1β in the brain contributing to anxiety.
- Methylphenidate prevents high-fat diet (HFD)-induced learning/memory impairment in juvenile mice.
- Central inhibition of interleukin-6 trans-signaling during peripheral infection reduced neuroinflammation and sickness in aged mice.
- IL-1 receptor 2 (IL-1R2) and its role in immune regulation.
- Hypoxia/Reoxygenation Impairs Memory Formation via Adenosine-Dependent Activation of Caspase 1.
- Mouse testing methods in psychoneuroimmunology: an overview of how to measure sickness, depressive/anxietal, cognitive, and physical activity behaviors.
- Development of a Lactobacillus specific T-RFLP method to determine lactobacilli diversity in complex samples.
- Individually ventilated cages cause chronic low-grade hypoxia impacting mice hematologically and behaviorally.
- The health benefits of dietary fiber: Beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer.
- The biobehavioral and neuroimmune impact of low-dose ionizing radiation.
- Macrophages make me sick: How macrophage activation states influence sickness behavior.
- Acute hypoglycemia causes depressive-like behaviors in mice.
- Fasting Induces an Anti-Inflammatory Effect on the Neuroimmune System Which a High-Fat Diet Prevents.
- Sickness behavior induced by endotoxin can be mitigated by the dietary soluble fiber, pectin, through up-regulation of IL-4 and Th2 polarization.
- Accelerated recovery from acute hypoxia in obese mice is due to obesity-associated up-regulation of interleukin-1 receptor antagonist.
- Psychoneuroimmune implications of type 2 diabetes: redux.
- Psychoneuroimmunology. Preface.
- Behavioral recovery from acute hypoxia is reliant on leptin.
- Acute hypoxia, diabetes, and neuroimmune dysregulation: converging mechanisms in the brain.
- Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system.
- Ca2+/calmodulin-dependent kinase kinase alpha is expressed by monocytic cells and regulates the activation profile.
- The implication of proinflammatory cytokines in type 2 diabetes.
- LPS-dependent suppression of social exploration is augmented in type 1 diabetic mice.
- Detection of Chlamydia trachomatis and Neisseria gonorrhoeae infections in North American women by testing SurePath liquid-based Pap specimens in APTIMA assays.
- Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to...
- Acute hypoxia activates the neuroimmune system, which diabetes exacerbates.
- Augmented lipopolysaccharide-induced TNF-alpha production by peritoneal macrophages in type 2 diabetic mice is dependent on elevated glucose and requires p38 MAPK.
- Phagocytosis of cholesteryl ester is amplified in diabetic mouse macrophages and is largely mediated by CD36 and SR-A.
- C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts.
- Psychoneuroimmune implications of type 2 diabetes.
- A reduced carbohydrate, increased protein diet stabilizes glycemic control and minimizes adipose tissue glucose disposal in rats.
- Cytokines in type 2 diabetes.
- Inhibition of vagally mediated immune-to-brain signaling by vanadyl sulfate speeds recovery from sickness.
- Test performance comparison of inform HPV and hybrid capture 2 high-risk HPV DNA tests using the SurePath liquid-based Pap test as the collection method.
- IL-1beta-mediated innate immunity is amplified in the db/db mouse model of type 2 diabetes.
- Leucine reduces the duration of insulin-induced PI 3-kinase activity in rat skeletal muscle.
- Proinflammatory cytokine impairment of insulin-like growth factor I-induced protein synthesis in skeletal muscle myoblasts requires ceramide.
- Additional collection devices used in conjunction with the SurePath Liquid-Based Pap Test broom device do not enhance diagnostic utility.
- Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.
- IL-1beta suppresses prolonged Akt activation and expression of E2F-1 and cyclin A in breast cancer cells.
- Tumor necrosis factor alpha inhibits cyclin A expression and retinoblastoma hyperphosphorylation triggered by insulin-like growth factor-I induction of new E2F-1 synth...
- Effectiveness of the SurePath liquid-based Pap test in automated screening and in detection of HSIL.
- Cytokine-hormone interactions: tumor necrosis factor alpha impairs biologic activity and downstream activation signals of the insulin-like growth factor I receptor in ...
- New red blood cell lysing fixative for use in fine needle aspiration and fluid cytology.
- Vanadate and rapamycin synergistically enhance insulin-stimulated glucose uptake.
- Proinflammatory cytokines block growth of breast cancer cells by impairing signals from a growth factor receptor.
- Dual sampling of the endocervix and its impact on AutoCyte Prep endocervical adequacy.
- Methylglyoxal enhances cisplatin-induced cytotoxicity by activating protein kinase Cdelta.
- Mouse Short- and Long-term Locomotor Activity Analyzed by Video Tracking Software.
- Loss of synaptic receptors can precede morphologic changes induced by alcoholism.
- Membrane fluidization increases low-affinity muscarinic receptor binding in brain: changes with aging.
- Use of annexin-V to demonstrate the role of phosphatidylserine exposure in the maintenance of haemostatic balance by endothelial cells.
- Binding of [125I]-insulin-like growth factor-1 (IGF-1) in brains of Alzheimer's and alcoholic patients.
- Insulin-like growth factor I receptor binding in brains of Alzheimer's and alcoholic patients.
- Clinical biochemistry of preeclampsia and related liver diseases of pregnancy: a review.
- Analysis of muscle microcirculation in advanced diabetes mellitus by contrast enhanced ultrasound.
- Cholinergic and serotonergic stimulation of phosphoinositide hydrolysis is decreased in Alzheimer''s disease.
- Activation of human protein C by blood coagulation factor Xa in the presence of anionic phospholipids. Enhancement by sulphated polysaccharides.
- IL-10 inhibits apoptosis of promyeloid cells by activating insulin receptor substrate-2 and phosphatidylinositol 3'-kinase.
- Tumor necrosis factor(alpha) and insulin-like growth factor-I in the brain: is the whole greater than the sum of its parts?
- Frap-dependent serine phosphorylation of IRS-1 inhibits IRS-1 tyrosine phosphorylation.
- CD45 negatively regulates monocytic cell differentiation by inhibiting phorbol 12-myristate 13-acetate-dependent activation and tyrosine phosphorylation of protein kin...
- Impact of qualified (indeterminate) diagnoses on the accuracy of renal, thyroid, and breast fine-needle aspiration biopsy.
- Investigation of three doses of oral insulin-like growth factor-I on jejunal lactase phlorizin hydrolase activity and gene expression and enterocyte proliferation and ...
- Developmental expression of insulin receptor substrate-2 during dimethylsulfoxide-induced differentiation of human HL-60 cells.
- JAK1-dependent phosphorylation of insulin receptor substrate-1 (IRS-1) is inhibited by IRS-1 serine phosphorylation.
- Elevated cyclin E levels, inactive retinoblastoma protein, and suppression of the p27(KIP1) inhibitor characterize early development of promyeloid cells into macrophages.
- Insulin activates caspase-3 by a phosphatidylinositol 3'-kinase-dependent pathway.
- Phosphatidylinositol 3'-kinase, but not S6-kinase, is required for insulin-like growth factor-I and IL-4 to maintain expression of Bcl-2 and promote survival of myeloi...
- Phosphatidylinositol 3''-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase.
- Activation of protein kinase C-zeta and phosphatidylinositol 3'-kinase and promotion of macrophage differentiation by insulin-like growth factor-I.
- Phosphatidylinositol 3'-kinase is associated with a serine kinase that is activated by okadaic acid.
- IL-4 and insulin-like growth factor-I inhibit the decline in Bcl-2 and promote the survival of IL-3-deprived myeloid progenitors.
- Activation of phosphatidylinositol 3'-kinase by insulin-like growth factor-I rescues promyeloid cells from apoptosis and permits their differentiation into granulocytes.
- Requirement for phosphatidylinositol 3'-kinase to protect hemopoietic progenitors against apoptosis depends upon the extracellular survival factor.
- The transmembrane protein-tyrosine phosphatase CD45 is associated with decreased insulin receptor signaling.
- Functional insulin and insulin-like growth factor-1 receptors are preferentially expressed in multiple myeloma cell lines as compared to B-lymphoblastoid cell lines.
- Anomalous ABO inheritance explained by ovum transplantation.
- Effect of pattern of aerosol inhalation on clearance of technetium-99m-labeled diethylenetriamine pentaacetic acid from the lungs of normal humans.
- Expression of a transmembrane phosphotyrosine phosphatase inhibits cellular response to platelet-derived growth factor and insulin-like growth factor-1.
- Macrophage hypo-responsiveness to interferon-gamma in aged mice is associated with impaired signaling through Jak-STAT.
- The PI3-kinase serine kinase phosphorylates its p85 subunit and IRS-1 in PI3-kinase/IRS-1 complexes.
- Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226.
- Interleukin-10 in the brain.
- IL-10 promotes survival of microglia without activating Akt.
- IL-4-dependent CD86 expression requires JAK/STAT6 activation and is negatively regulated by PKCdelta.
- Medical students who decompress during the M-1 year outperform those who fail and repeat it: a study of M-1 students at the University of Illinois College of Medicine ...
- Gender plays no role in student ability to perform on computer-based examinations.
- Novel activity of an anti-inflammatory cytokine: IL-10 prevents TNFalpha-induced resistance to IGF-I in myoblasts.
- From inflammation to sickness and depression: when the immune system subjugates the brain.
- Blocking of beta-2 adrenergic receptors hastens recovery from hypoglycemia-associated social withdrawal.
- Macropinocytosis is decreased in diabetic mouse macrophages and is regulated by AMPK.
- Market survey predictions on the future of US Pap testing.
- Collection of the BD SurePath Pap Test with a broom device plus endocervical brush improves disease detection when compared to the broom device alone or the spatula pl...
- Effect of live-fire training drills on firefighters'' platelet number and function.
Schools
University Of Rochester
Strong Mem Hsp University Rochester
Doctors Specialties
- Cytopathology
- Pathology
Accepted Insurances
Education
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University of Rochester -
University of Rochester School of Medicine and Dentistry
Hospital
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Carle Foundation Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1568685964 |
| Last Name Of The Provider | FREUND |
| First Name Of The Provider | GREGORY |
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