Physician
Internal Medicine
Dr. Gordon Gill, MD
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Gordon Gill practices Internal Medicine. He went to medical school at Vanderbilt University School of Medicine. He has 2 awards "Elected Member" and "Whos Who in Medicine and Healthcare". Gordon Gill is also published. He has 101 publications published. The lastest publication: "Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis.'
Publications
- Viewing serine/threonine protein phosphatases through the eyes of drug designers.
- Thyrotropin-stimulated phosphorylation of high mobility group protein 14 in vivo at the site catalyzed by cyclic nucleotide-dependent protein kinases in vitro.
- Identity of the in vivo phosphorylation site in high mobility group 14 protein in HeLa cells with the site phosphorylated by casein kinase II in vitro.
- Activation of hormone-sensitive lipase and phosphorylase kinase by purified cyclic GMP-dependent protein kinase.
- Purification and characterization of 3'':5''-cyclic GMP-dependent protein kinase.
- Surgical management of the thyroid nodule: patient selection based on the results of fine-needle aspiration cytology.
- Guanosine 3'',5''-monophosphate-dependent protein kinase.
- Control of bovine adrenal cortical cell proliferation by fibroblast growth factor. Lack of effect of epidermal growth factor.
- Purification of functionally active epidermal growth factor receptor protein using a competitive antagonist monoclonal antibody and competitive elution with epidermal ...
- Anti-pp60src antibodies are substrates for EGF-stimulated protein kinase.
- Purification and properties of thyroid hormone receptor beta 1 expressed in Escherichia coli as a fusion protein.
- Direct binding of eps8 to the juxtamembrane domain of EGFR is phosphotyrosine- and SH2-independent.
- Phosphorylation of ribosome-associated protein by an adenosine 3'':5''-cyclic monophosphate-dependent protein kinase: location of the microsomal receptor and protein k...
- Coexpression of both alpha and beta subunits is required for assembly of regulated casein kinase II.
- Regulation of cyclic nucleotide-dependent protein kinase activity by histones and poly(L-arginine).
- Expression cloning of human EGF receptor complementary DNA: gene amplification and three related messenger RNA products in A431 cells.
- Protein effects on the activity of guanosine 3':5'-monophosphate-dependent protein kinase.
- Epidermal growth factor and its receptor.
- Growth factors, receptors and oncogenes.
- Effects of epidermal growth factor receptor concentration on tumorigenicity of A431 cells in nude mice.
- Comparison of protein phosphorylations in variant A431 cells with different growth responses to epidermal growth factor.
- Protein-protein interaction of zinc finger LIM domains with protein kinase C.
- Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells.
- The EGF receptor: structure, regulation and potential role in malignancy.
- Receptor tyrosine kinases.
- Regulation of gene expression by epidermal growth factor.
- Role of epidermal growth factor-stimulated protein kinase in control of proliferation of A431 cells.
- Structural features of the 5'' region of the human erbB-2 gene.
- Relationship between production of epidermal growth factor receptors, gene amplification, and chromosome 7 translocation in variant A431 cells.
- Regulation of EGF receptor expression and function.
- Regulation of the epidermal growth factor receptor by phosphorylation.
- Identification of phosphorylation sites: use of the epidermal growth factor receptor.
- Positive and negative regulatory elements in the human erbB-2 gene promoter.
- Production of an epidermal growth factor receptor-related protein.
- Interaction between the epidermal growth factor receptor and phosphoinositide kinases.
- Separation and characterization of a phosphatidylinositol kinase activity that co-purifies with the epidermal growth factor receptor.
- Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis.
- Immunoaffinity purification of the epidermal growth factor receptor. Stoichiometry of binding and kinetics of self-phosphorylation.
- Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding ...
- Regulated migration of epidermal growth factor receptor from caveolae.
- The enigma of LIM domains.
- C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.
- Involvement of ErbB2 in the signaling pathway leading to cell cycle progression from a truncated epidermal growth factor receptor lacking the C-terminal autophosphoryl...
- Epidermal growth factor stimulates phosphorylation of RAF-1 independently of receptor autophosphorylation and internalization.
- Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain.
- Self-phosphorylation enhances the protein-tyrosine kinase activity of the epidermal growth factor receptor.
- Epidermal growth factor stimulates a protein tyrosine kinase which is separable from the epidermal growth factor receptor.
- Structural features of LIM kinase that control effects on the actin cytoskeleton.
- Structure and inducible regulation of the human c-erb B2/neu promoter.
- Reversibility of the epidermal growth factor receptor self-phosphorylation reaction. Evidence for formation of a high energy phosphotyrosine bond.
- Analysis of morphology and receptor metabolism in clonal variant A431 cells with differing growth responses to epidermal growth factor.
- Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain.
- The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis.
- A negative feedback loop attenuates EGF-induced morphological changes.
- LIM domain recognition of a tyrosine-containing tight turn.
- Relation of epidermal growth factor receptor concentration to growth of human epidermoid carcinoma A431 cells.
- Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics.
- Shc and Enigma are both required for mitogenic signaling by Ret/ptc2.
- Regulatory features of the epidermal growth factor receptor.
- Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor.
- A heterodimeric nuclear protein complex binds two palindromic sequences in the proximal enhancer of the human erbB-2 gene.
- Altered epidermal growth factor (EGF)-stimulated protein kinase activity in variant A431 cells with altered growth responses to EGF.
- Regulation of the ERBB-2 promoter by RBPJkappa and NOTCH.
- Regulation of epidermal growth factor receptor gene expression.
- Identification and characterization of a regulated promoter element in the epidermal growth factor receptor gene.
- Effect of carboxyl terminal truncation on the tyrosine kinase activity of the epidermal growth factor receptor.
- A nuclear protein is required for thyroid hormone receptor binding to an inhibitory half-site in the epidermal growth factor receptor promoter.
- Specific factors are required for kinase-dependent endocytosis of insulin receptors.
- The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor.
- Expression and purification of the epidermal growth factor receptor extracellular domain utilizing a polycistronic expression system.
- Enhanced tumorigenesis of NR6 cells which express non-down-regulating epidermal growth factor receptors.
- Analysis of substrate recognition determinants in a synthetic peptide containing the Tyr 1173 autophosphorylation site of the epidermal growth factor receptor.
- A basic residue, Lys 782, composes part of the ATP-binding site on the epidermal growth factor receptor tyrosine kinase.
- Epidermal growth factor receptor threonine and serine residues phosphorylated in vivo.
- The intracellular tyrosine kinase domain of the epidermal growth factor receptor undergoes a conformational change upon autophosphorylation.
- Ligand-activated thyroid hormone and retinoic acid receptors inhibit growth factor receptor promoter expression.
- Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms.
- Structural features that specify tyrosine kinase activity deduced from homology modeling of the epidermal growth factor receptor.
- T3 receptor suppression of Sp1-dependent transcription from the epidermal growth factor receptor promoter via overlapping DNA-binding sites.
- RGS-PX1, a GAP for GalphaS and sorting nexin in vesicular trafficking.
- Ligand-induced endocytosis of epidermal growth factor receptors that are defective in binding adaptor proteins.
- Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosp...
- Phosphorylation of the epidermal growth factor receptor at threonine 654 inhibits ligand-induced internalization and down-regulation.
- Activation of the purified protein tyrosine kinase domain of the epidermal growth factor receptor.
- The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phospho...
- Mutational analysis of the nucleotide binding site of the epidermal growth factor receptor and v-Src protein-tyrosine kinases.
- Alteration of epidermal growth factor receptor activity by mutation of its primary carboxyl-terminal site of tyrosine self-phosphorylation.
- Structure and function of LIM domains.
- The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelia...
- A site of tyrosine phosphorylation in the C terminus of the epidermal growth factor receptor is required to activate phospholipase C.
- Specificity of LIM domain interactions with receptor tyrosine kinases.
- Enhanced degradation of EGF receptors by a sorting nexin, SNX1.
- Association of epidermal growth factor receptors with coated pit adaptins via a tyrosine phosphorylation-regulated mechanism.
- Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis.
- Mutational removal of the Thr669 and Ser671 phosphorylation sites alters substrate specificity and ligand-induced internalization of the epidermal growth factor receptor.
- Analysis of functional domains in the epidermal growth factor receptor using site-directed mutagenesis.
- A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity.
- Role of intrinsic protein tyrosine kinase in function and metabolism of the epidermal growth factor receptor.
- Chip is an essential cofactor for apterous in the regulation of axon guidance in Drosophila.
- Ligand-induced transformation by a noninternalizing epidermal growth factor receptor.
Schools
Vanderbilt University
Vanderbilt University Hospital
Yale New Haven Hospital
Yale
Doctors Specialties
- Internal Medicine
Accepted Insurances
Awards
- Elected Member
- Whos Who in Medicine and Healthcare
Education
-
Yale-New Haven Hospital -
Vanderbilt University -
Vanderbilt University School of Medicine
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