Hematology/Oncology at VA Medical Center and University of California, Irvine
Hematology
Dr. Gordon D. McLaren, MD
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Dr. Gordon D. McLaren is an expert in the field of Hematology. He went to Stanford University School of Medicine. Stanford University School of Medicine is a top medical university. Stanford University School of Medicine is ranked 2 in research and 25 in primary care medicine Gordon McLaren has written publications. He has 66 publications published with PubMed. The lastest paper is: 'Screening for hemochromatosis in primary care settings.'
Publications
- Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload.
- Elevated transferrin saturation, health-related quality of life and telomere length.
- Association between celiac disease and iron deficiency in Caucasians, but not non-Caucasians.
- Randomized trial of physician alerts for thromboprophylaxis after discharge.
- Telomere length and elevated iron: The influence of phenotype and HFE genotype.
- Associations between Single Nucleotide Polymorphisms in Iron-Related Genes and Iron Status in Multiethnic Populations.
- New mechanistic explanation for the localization of ulcers in the rat duodenum: Role of iron and selective uptake of cysteamine.
- Probability of C282Y homozygosity decreases as liver transaminase activities increase in participants with hyperferritinemia in the HEIRS Study.
- IRon overload screeNing tool (IRON): Development of a tool to guide screening in primary care.
- Genome-wide association study identifies genetic Loci associated with iron deficiency.
- A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis.
- Heritability of serum iron measures in the hemochromatosis and iron overload screening (HEIRS) family study.
- Role of iron in the pathogenesis of cysteamine-induced duodenal ulceration in rats.
- Physician alerts to prevent symptomatic venous thromboembolism in hospitalized patients.
- Heme carrier protein 1 (HCP1) genetic variants in the Hemochromatosis and Iron Overload Screening (HEIRS) Study participants.
- Iron absorption and metabolism.
- HFE C282Y homozygosity is associated with lower total and low-density lipoprotein cholesterol: The hemochromatosis and iron overload screening study.
- Hereditary hemochromatosis: insights from the Hemochromatosis and Iron Overload Screening (HEIRS) Study.
- Serum ferritin concentrations and body iron stores in a multicenter, multiethnic primary-care population.
- Accuracy of family history of hemochromatosis or iron overload: the hemochromatosis and iron overload screening study.
- Biological variability of transferrin saturation and unsaturated iron-binding capacity.
- African Americans at risk for increased iron stores or liver disease.
- Association of ferroportin Q248H polymorphism with elevated levels of serum ferritin in African Americans in the Hemochromatosis and Iron Overload Screening (HEIRS) St...
- Serum ferritin and transferrin saturation in Asians and Pacific Islanders.
- Hemochromatosis (HFE) gene splice site mutation IVS5+1 G/A in North American Vietnamese with and without phenotypic evidence of iron overload.
- Mixture models of serum iron measures in population screening for hemochromatosis and iron overload.
- Relationships of serum ferritin, transferrin saturation, and HFE mutations and self-reported diabetes in the Hemochromatosis and Iron Overload Screening (HEIRS) study.
- Iron metabolism in the hemoglobin-deficit mouse: correlation of diferric transferrin with hepcidin expression.
- Comparison of the unsaturated iron-binding capacity with transferrin saturation as a screening test to detect C282Y homozygotes for hemochromatosis in 101,168 particip...
- Concerns in a primary care population about genetic discrimination by insurers.
- Initial screening transferrin saturation values, serum ferritin concentrations, and HFE genotypes in whites and blacks in the Hemochromatosis and Iron Overload Screeni...
- Comparison of sampling methods for obtaining accurate coagulation values in hemodialysis patients with heparinized central venous catheters.
- Iodine and goiter in children.
- Iron absorption in normal and iron-deficient beagle dogs: mucosal iron kinetics.
- Antigranulocyte antibodies and deranged immune function associated with phenytoin-induced serum sickness.
- Reticuloendothelial iron stores and hereditary hemochromatosis: a paradox.
- Erythrocyte protoporphyrin in the detection of iron deficiency.
- A model of intestinal iron absorption and plasma iron kinetics: optimal parameter estimates for normal dogs.
- Computer simulation of iron absorption: regulation of mucosal and systemic iron kinetics in dogs.
- Control of iron absorption in hemochromatosis. Mucosal iron kinetics in vivo.
- Regulation of intestinal iron absorption and mucosal iron kinetics in hereditary hemochromatosis.
- Hyperferremia in immunosuppressed patients with acute nonlymphocytic leukemia and the risk of infection.
- Patient-specific analysis of sequential haematological data by multiple linear regression and mixture distribution modelling.
- Iron overload disorders: natural history, pathogenesis, diagnosis, and therapy.
- HFE genotype in patients with hemochromatosis and other liver diseases.
- Arthritis of hemochromatosis. Clinical spectrum, relation to histocompatibility antigens, and effectiveness of early phlebotomy.
- Arthropathy, hypouricemia and normal serum iron studies in hereditary hemochromatosis.
- Etiologies, consequences, and treatment of iron overload.
- Evidence for heterogeneity in hereditary hemochromatosis. Evaluation of 174 persons in nine families.
- Screening for hemochromatosis in primary care settings.
- Distribution of transferrin saturation in an Australian population: relevance to the early diagnosis of hemochromatosis.
- A genome-wide linkage scan for iron phenotype quantitative trait loci: the HEIRS Family Study.
- Serial serum ferritin measurements in untreated HFE C282Y homozygotes in the Hemochromatosis and Iron Overload Screening Study.
- Mapping the gene for sex-linked Anemia: an inherited defect of intestinal iron absorption in the mouse.
- Delayed hepcidin response explains the lag period in iron absorption following a stimulus to increase erythropoiesis.
- Relationship between transferrin saturation and iron stores in the African American and US Caucasian populations: analysis of data from the third National Health and N...
- Hemochromatosis and Iron Overload Screening (HEIRS) study design for an evaluation of 100,000 primary care-based adults.
- Liver diseases in the hemochromatosis and iron overload screening study.
- Hemochromatosis and iron-overload screening in a racially diverse population.
- Geographic and racial/ethnic differences in HFE mutation frequencies in the Hemochromatosis and Iron Overload Screening (HEIRS) Study.
- Clinical manifestations of hemochromatosis in HFE C282Y homozygotes identified by screening.
- HFE C282Y homozygotes aged 25-29 years at HEIRS Study initial screening.
- Characteristics of participants with self-reported hemochromatosis or iron overload at HEIRS study initial screening.
- Measurement of sulfur-containing compounds involved in the metabolism and transport of cysteamine and cystamine. Regional differences in cerebral metabolism.
- Screening for iron overload: lessons from the hemochromatosis and iron overload screening (HEIRS) study.
Schools
Stanford University
Mary Imogene Bassett Hospital
Case Western Reserve University
University Hosps
Conditions Treated
- Adrenal Gland Cancer
- Anemia
- Breast Cancer
- Colorectal Cancer
- View All
Doctors Specialties
- Hematology
- Medical Oncology
- Oncology
Accepted Insurances
Education
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Case Western Reserve University - University Hospitals -
Stanford University School of Medicine
Hospital
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UC Irvine Medical Center
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