Professor, Pathology, University of Alabama School of Medicine
Pathology
Dr. Gene P. Siegal, MD
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Gene P. Siegal is an expert in the field of Pathology. He studied medicine at University of Louisville School of Medicine. University of Louisville School of Medicine has a rank of 83 in research and a 0 in primary care He over the years received 1 awards: "Top MD". Gene P. Siegal, MD is also a published doctor. He has 99 paper published. The most recent paper is: Flexor Tendon Repair With a Knotless, Bidirectional Barbed Suture: An In Vivo Biomechanical Analysis. Gene Siegal accepts Medicare.
Publications
- Flexor Tendon Repair With a Knotless, Bidirectional Barbed Suture: An In Vivo Biomechanical Analysis.
- Autosomal-dominant familial angiolipomatosis.
- The Utility of Phosphohistone H3 in Breast Cancer Grading.
- Targeting the effector domain of the myristoylated alanine rich C-kinase substrate enhances lung cancer radiation sensitivity.
- Subsets of airway myeloid-derived regulatory cells distinguish mild asthma from chronic obstructive pulmonary disease.
- GSK3β-dependent inhibition of AMPK potentiates activation of neutrophils and macrophages, and enhances severity of acute lung injury.
- Round cell tumors of bone: an update on recent molecular genetic advances.
- Diet modulation is an effective complementary agent in preventing and treating breast cancer lung metastasis.
- Changing prognostic factors in osteosarcoma: analysis of 381 cases from two institutions.
- Prognostic factors in patients with metastatic breast cancer at the time of diagnosis.
- Finding a new generation of spies and manuscript reviewers.
- Enhancement of antitumor immunity in lung cancer by targeting myeloid-derived suppressor cell pathways.
- Syndecan-1 overexpression is associated with nonluminal subtypes and poor prognosis in advanced breast cancer.
- A phase I clinical trial of Ad5/3-Δ24, a novel serotype-chimeric, infectivity-enhanced, conditionally-replicative adenovirus (CRAd), in patients with recurrent ovarian...
- Epiphyseal chondromyxoid fibroma with prominent adipose tissue: an unusual radiologic and histologic presentation.
- Expression of osteoprotegerin from a replicating adenovirus inhibits the progression of prostate cancer bone metastases in a murine model.
- Alpha-CaMKII plays a critical role in determining the aggressive behavior of human osteosarcoma.
- Gene transfer of active Akt1 by an infectivity-enhanced adenovirus impacts β-cell survival and proliferation differentially in vitro and in vivo.
- Glycoengineering in cancer therapeutics: a review with fucose-depleted trastuzumab as the model.
- Depletion of Plasmacytoid Dendritic Cells Inhibits Tumor Growth and Prevents Bone Metastasis of Breast Cancer Cells.
- The Dark Side of Publishing: Promoting Ethics in AJP 2003 to 2008.
- Nicotine exposure and the progression of chronic kidney disease: role of the α7-nicotinic acetylcholine receptor.
- A Phase I Clinical Trial of Ad5.SSTR/TK.RGD, a Novel Infectivity-Enhanced Bicistronic Adenovirus, in Patients with Recurrent Gynecologic Cancer.
- Regeneration of pancreatic non-β endocrine cells in adult mice following a single diabetes-inducing dose of streptozotocin.
- Bilateral Mesenchymal Hamartoma of the Chest Wall in an Infant Boy.
- Intracranial meningeal hemangiopericytoma metastatic to the scapula.
- A 23-year-old woman with a right femoral neck fracture.
- The emerging importance of ?-L-fucose in human breast cancer: a review.
- Interleukin-4 inhibits RANKL-induced NFATc1 expression via STAT6: A novel mechanism mediating its blockade of osteoclastogenesis.
- Complex analysis of a recurrent pleomorphic hyalinizing angiectatic tumor of soft parts.
- Elevated levels of NO are localized to distal airways in asthma.
- Characterization of CXCR4 expression in chondrosarcoma of bone.
- Evaluation of lymph node numbers for adequate staging of Stage II and III colon cancer.
- Prevention of carcinogenesis and inhibition of breast cancer tumor burden by dietary stearate.
- Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis.
- LL-37 as a therapeutic target for late stage prostate cancer.
- Metastatic inflammatory myofibroblastic tumor identified by EUS-FNA in mediastinal lymph nodes with ancillary FISH studies for ALK rearrangement.
- Breast carcinomas with isolated bone metastases have different hormone receptor expression profiles than those with metastases to other sites or multiple organs.
- A New Generation of Serotype Chimeric Infectivity-Enhanced Conditionally Replicative Adenovirals: The Safety Profile of Ad5/3-Δ24 in Advance of a Phase I ...
- Conditionally replicating adenovirus expressing TIMP2 for ovarian cancer therapy.
- Conditionally Replicating Adenovirus Expressing TIMP2 Increases Survival in a Mouse Model of Disseminated Ovarian Cancer.
- Juxtatumoral stromal reactions in uterine endometrioid adenocarcinoma and their prognostic significance.
- A phase I study of a tropism-modified conditionally replicative adenovirus for recurrent malignant gynecologic diseases.
- Merkel cell carcinoma: correlation of KIT expression with survival and evaluation of KIT gene mutational status.
- Aggressive osteoblastoma: a case report involving a unique chromosomal aberration.
- Ex vivo transfer of the Hoxc-8-interacting domain of Smad1 by a tropism-modified adenoviral vector results in efficient bone formation in a rabbit model of spinal fusion.
- What editors want in an abstract.
- Small cell tumors of bone.
- E-cadherin/beta-catenin and CD10: a limited immunohistochemical panel to distinguish pancreatic endocrine neoplasm from solid pseudopapillary neoplasm of the pancreas ...
- Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in prostate cancer bone metastasis.
- Novel infectivity-enhanced oncolytic adenovirus with a capsid-incorporated dual-imaging moiety for monitoring virotherapy in ovarian cancer.
- Identifying the safety profile of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in anticipation of a phase I clinical trial in patients with re...
- Adenovirus infection activates akt1 and induces cell proliferation in pancreatic islets1.
- Navigating interpersonal conflict and peer review.
- Stearate preferentially induces apoptosis in human breast cancer cells.
- Unplanned surgical excision of extremity soft tissue sarcomas: patient profile and referral patterns.
- Who's on first?
- Role of oxygen availability in CFTR expression and function.
- Thy-1 promoter hypermethylation: a novel epigenetic pathogenic mechanism in pulmonary fibrosis.
- Reporting guidelines for clinical laboratory reports in surgical pathology.
- Large, clear cytoplasmic vacuolation: an under-recognized cytologic clue to distinguish solid pseudopapillary neoplasms of the pancreas from pancreatic endocrine neopl...
- Silencing of transforming growth factor-beta1 in situ by RNA interference for breast cancer: implications for proliferation and migration in vitro and metastasis in vivo.
- Mitochondrial respiratory complex I regulates neutrophil activation and severity of lung injury.
- A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.
- Juvenile juxtacortical chondromyxoid fibroma of bone: a case report.
- Systemic osteoprotegerin gene therapy restores tumor-induced bone loss in a therapeutic model of breast cancer bone metastasis.
- Intracranial metastasis from synovial sarcoma.
- p53 Nuclear accumulation and Bcl-2 expression in contiguous adenomatous components of colorectal adenocarcinomas predict aggressive tumor behavior.
- Solid pseudopapillary tumor of the pancreas: a review of salient clinical and pathologic features.
- Involvement of vitronectin in lipopolysaccaride-induced acute lung injury.
- Juxtacortical chondromyxoid fibroma of bone: a unique variant: a case study of 20 patients.
- alpha-CaMKII controls the growth of human osteosarcoma by regulating cell cycle progression.
- An 18-year-old Man with Knee Pain.
- A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo syste...
- Stromal cell-derived factor 1 promotes angiogenesis via a heme oxygenase 1-dependent mechanism.
- Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer.
- p38 MAPK as a potential therapeutic target for inflammatory osteolysis.
- Solid-pseudopapillary neoplasm of the pancreas: Three cases with a literature review.
- Administration of a conditionally replicative oncolytic canine adenovirus in normal dogs.
- Signal transduction cross-talk during colorectal tumorigenesis.
- Targeting mesothelioma using an infectivity enhanced survivin-conditionally replicative adenoviruses.
- Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma.
- Osteosarcoma: anatomic and histologic variants.
- The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma.
- Desmoplastic fibroma of the jaw: a case report and review of literature.
- Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system.
- Cytologic grade independently predicts survival of patients with pancreatic adenocarcinoma.
- Loss of fibroblast Thy-1 expression correlates with lung fibrogenesis.
- Optimal molecular profiling of tissue and tissue components: defining the best processing and microdissection methods for biomedical applications.
- Adenoviruses with an RGD-4C modification of the fiber knob elicit a neutralizing antibody response but continue to allow enhanced gene delivery.
- A fiber-modified, secretory leukoprotease inhibitor promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.
- Productive replication of human adenovirus type 5 in canine cells.
- A 32-year-old man with knee pain.
- Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis.
- Ulnar mass in a 51-year-old woman.
- An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism.
- A 36-year-old woman with a toe mass.
- MUC1 and MUC2 expression in pancreatic ductal carcinoma obtained by fine-needle aspiration.
Schools
University of Louisville School of Medicine
Mayo Grad School Med
University Of Minnesota
Doctors Specialties
- Anatomic Pathology
- Pathology
Accepted Insurances
Awards
- Top MD
Education
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Mayo School of Graduate Medical Education -
University of Louisville School of Medicine
Hospital
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University of Alabama Hospital -
Birmingham Veterans Affairs Medical Center
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1487706461 |
| Last Name Of The Provider | SIEGAL |
| First Name Of The Provider | GENE |
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