Professor of Neurological Surgery, UCLA-David Geffen School of Medicine
Neurosurgery
Dr. Gary W. Mathern, MD
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Gary Mathern works in the field of Neurosurgery. He researched medicine at Case Western Reserve University School of Medicine. He received 4 awards: "Top Doctors:LA Area", "Top Doctors:Southern California", "Super Doctor" and "Fellow (FAANS)". Doctor Gary W. Mathern, MD is also a published physician. He has 100 paper published. The most recent paper is: Hippocampal and entorhinal cortex high-frequency oscillations (100--500 Hz) in human epileptic brain and in kainic acid--treated rats with chronic seizures. Gary W. Mathern, MD is registered with Medicare.
Publications
- Comments from the Editor(s).
- An AKT3-FOXG1-reelin network underlies defective migration in human focal malformations of cortical development.
- Literacy after Cerebral hemispherectomy: Can the isolated right hemisphere read?
- In Rasmussen Encephalitis, Hemichannels Associated with Microglial Activation are linked to Cortical Pyramidal Neuron Coupling: A Possible Mechanism for Cellular Hyper...
- Should consciousness describe seizures and what terms should be applied? Epilepsia's survey results.
- Who's responsible to refer for Epilepsy surgery? We all are!
- From the Editors: Epilepsia's 2014 Operational Definition of Epilepsy Survey.
- Basic Mechanisms of Epileptogenesis in Pediatric Cortical Dysplasia.
- Fewer specialists support using medical marijuana and CBD in treating Epilepsy patients compared with other medical professionals and patients: Result of Epilepsia's s...
- Reasons for discrepancy between incidence and prevalence of Epilepsy in lower income countries: Epilepsia's survey results.
- From the Editors: Epilepsia's survey on the necessity of the Wada test and intracranial electrodes for cortical mapping.
- A practical clinical definition of Epilepsy.
- Diagnostic test utilization in evaluation for resective Epilepsy surgery in children.
- Epilepsia editorial: Publications by country.
- Pacemaker GABA synaptic activity may contribute to network synchronization in pediatric cortical dysplasia.
- Time to pediatric Epilepsy surgery is longer and developmental outcomes lower for government compared with private insurance.
- Outcomes for temporal lobe Epilepsy operations may not be equal: A call for an RCT of ATL vs SAH.
- Hemimegalencephaly, a paradigm for somatic postzygotic neurodevelopmental disorders.
- Time to pediatric Epilepsy surgery is related to disease severity and nonclinical factors.
- Vagal nerve stimulation for pharmacoresistant Epilepsy in children.
- Functionalized Magnetonanoparticles in Visualization of Intracranial Tumors on MRI.
- Synaptoneurosome micromethod for fractionation of mouse and human Brain, and primary neuronal cultures.
- The future is here: Web-based eight-question tool to determine Epilepsy surgery evaluation.
- Pediatric Epilepsy Surgery: Long-Term Five-Year Seizure Remission and Medication Usage.
- Intimal thickening of meningeal arteries after serial corticectomies for Rasmussen encephalitis.
- Neuroimaging in the definition and organization of the epilepsies: We're not there yet.
- De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly.
- The International League Against Epilepsy at the threshold of its second century: Year 2.
- Cerebral hemispherectomy: Sensory scores before and after intensive mobility training.
- Enhanced GABAergic network and receptor function in pediatric cortical dysplasia Type IIB compared with Tuberous Sclerosis Complex.
- The International League Against Epilepsy at the threshold of its second century: year 1.
- Utility of ictal SPECT in mesial temporal lobe Epilepsy with hippocampal atrophy: a randomized trial.
- Cerebral hemispherectomy: when half a Brain is good enough.
- Mesial temporal lobe Epilepsy: How do we improve surgical outcome?
- Comparative study of cellular and synaptic abnormalities in Brain tissue samples from pediatric tuberous sclerosis complex and cortical dysplasia type II.
- Interneurons, GABAA currents, and subunit composition of the GABAA receptor in type I and type II cortical dysplasia.
- Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005-2009.
- "Primary" leptomeningeal medulloblastoma.
- Challenges in the surgical treatment of Epilepsy patients with cortical dysplasia.
- Cortical dysplasia with prominent Rosenthal fiber formation in a case of intractable pediatric Epilepsy.
- Assessment and surgical outcomes for mild type I and severe type II cortical dysplasia: a critical review and the UCLA experience.
- Increased activation of Iba1+ microglia in pediatric Epilepsy patients with Rasmussen's encephalitis compared with cortical dysplasia and tuberous sclerosis complex.
- Constraint-induced movement therapy for individuals after Cerebral hemispherectomy: a case series.
- Epilepsy surgery patients with cortical dysplasia: present and future therapeutic challenges.
- Pyramidal cell responses to gamma-aminobutyric acid differ in type I and type II cortical dysplasia.
- Locomotor training remodels fMRI sensorimotor cortical activations in children after Cerebral hemispherectomy.
- Increased fast ripple to ripple ratios correlate with reduced hippocampal volumes and neuron loss in temporal lobe Epilepsy patients.
- Cytomegalic interneurons: a new abNormal cell type in severe pediatric cortical dysplasia.
- A hypothesis regarding the pathogenesis and epileptogenesis of pediatric cortical dysplasia and hemimegalencephaly based on MRI Cerebral volumes and NeuN cortical cell...
- Immature neurons and GABA networks may contribute to epileptogenesis in pediatric cortical dysplasia.
- Childhood-onset temporal lobe Epilepsy: neuroimaging predicts seizure control.
- Improving MRI differentiation of gray and white matter in epileptogenic lesions based on nonlinear feedback.
- Epileptogenesis in pediatric cortical dysplasia: the dysmature Cerebral developmental hypothesis.
- FDG-PET/MRI coregistration and diffusion-tensor imaging distinguish epileptogenic tubers and cortex in patients with tuberous sclerosis complex: a preliminary report.
- Status epilepticus and frequent seizures: incidence and clinical characteristics in pediatric Epilepsy surgery patients.
- Human cortical dysplasia and Epilepsy: an ontogenetic hypothesis based on volumetric MRI and NeuN neuronal density and size measurements.
- Are cytomegalic neurons and balloon cells generators of epileptic activity in pediatric cortical dysplasia?
- NMDA receptor alterations in neurons from pediatric cortical dysplasia tissue.
- Five or more acute postoperative seizures predict hospital course and long-term seizure control after hemispherectomy.
- Cerebral hemispherectomy in pediatric patients with epilepsy: comparison of three techniques by pathological substrate in 115 patients.
- Enhanced expression of a specific hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN) in surviving dentate gyrus granule cells of human and experi...
- Morphological and electrophysiological characterization of abNormal cell types in pediatric cortical dysplasia.
- Vascular genomics of the human Brain.
- Seizures decrease postnatal neurogenesis and granule cell development in the human fascia dentata.
- Impairment of Mitochondria in Adult Mouse Brain Overexpressing Predominantly Full-Length, N-Terminally Acetylated Human α-Synuclein.
- Differential expression of interferon-γ and chemokine genes distinguishes Rasmussen encephalitis from cortical dysplasia and provides evidence for an early Th1 immune ...
- Definition of drug resistant Epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies.
- The clinicopathologic spectrum of focal cortical dysplasias: a consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission.
- Therapy discovery for pharmacoresistant Epilepsy and for disease-modifying therapeutics: summary of the NIH/NINDS/AES models II workshop.
- Developmental outcome with and without successful intervention.
- [Determination of physiologic disturbances due to rotating shift schedules using ambulatory measurement of the arterial Pressure].
- Twenty-four-hour ambulatory blood Pressure in shift workers.
- [Ambrosia and the study of its dissemination].
- [Chewing tobacco. An emerging habit among adolescents].
- Noninvasive testing, early surgery, and seizure freedom in tuberous sclerosis complex.
- Variable anisotropic Brain electrical conductivities in epileptogenic foci.
- Improved outcomes in pediatric Epilepsy surgery: the UCLA experience, 1986-2008.
- Removing interictal fast ripples on electrocorticography linked with seizure freedom in children.
- FDG-PET/MRI coregistration improves detection of cortical dysplasia in patients with Epilepsy.
- Spoken language outcomes after hemispherectomy: factoring in etiology.
- Lobar and multilobar resections for medically intractable pediatric Epilepsy.
- Effect of theophylline and trimethobenzamide when given during kainate-induced status epilepticus: an improved histopathologic rat model of human hippocampal sclerosis.
- Neurons recorded from pediatric Epilepsy surgery patients with cortical dysplasia.
- Postoperative seizure control and antiepileptic drug use in pediatric Epilepsy surgery patients: the UCLA experience, 1986-1997.
- Cerebral cortical dysplasia: giant neurons show potential for increased excitation and axonal plasticity.
- Electrophysiological and morphological analyses of cortical neurons obtained from children with catastrophic Epilepsy: dopamine receptor modulation of glutamatergic re...
- Developmental changes in NMDA-induced intrinsic optical signals in the hippocampal dentate gyrus of children with medically intractable seizures.
- Electrophysiologic analysis of a chronic seizure model after unilateral hippocampal KA injection.
- Hippocampal N-methyl-D-aspartate receptor subunit mRNA levels in temporal lobe Epilepsy patients.
- Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe Epilepsy.
- Hippocampal and entorhinal cortex high-frequency oscillations (100--500 Hz) in human epileptic Brain and in kainic acid--treated rats with chronic seizures.
- Hippocampal AMPA and NMDA mRNA levels correlate with aberrant fascia dentata mossy fiber sprouting in the pilocarpine model of spontaneous limbic Epilepsy.
- Altered hippocampal kainate-receptor mRNA levels in temporal lobe Epilepsy patients.
- Hippocampal AMPA and NMDA mRNA levels and subunit immunoreactivity in human temporal lobe Epilepsy patients and a rodent model of chronic mesial limbic Epilepsy.
- Increased hippocampal AMPA and NMDA receptor subunit immunoreactivity in temporal lobe Epilepsy patients.
- Anoxia during kainate status epilepticus shortens behavioral convulsions but generates hippocampal neuron loss and supragranular mossy fiber sprouting.
- Human hippocampal AMPA and NMDA mRNA levels in temporal lobe Epilepsy patients.
- Astrocytes may contribute to the latent period in progressive neuron loss, axon sprouting, and chronic seizures in rat kainate hippocampal Epilepsy.
- Severe seizures in young children are associated with hippocampal neuron losses and aberrant mossy fiber sprouting during fascia dentata postnatal development.
Schools
Case Western Reserve University School of Medicine
Cleveland Clinic Foundation
UCLA School Med Chs
Procedures Preformed
- Cerebrospinal Fluid (CSF) Shunt - Insertion, Repair or Removal
- Craniectomy, Craniotomy, Surgery of Skull Base, Neuroendoscopy
- Deep Brain Stimulation
Conditions Treated
- Brain Aneurysm
- Cerebral Hemorrhage
- Epilepsy
- Hydrocephalus
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Doctors Specialties
- Neurosurgery
Accepted Insurances
Awards
- Top Doctors:LA Area
- Top Doctors:Southern California
- Super Doctor
- Fellow (FAANS)
Education
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UCLA Medical Center -
Harbor - UCLA Medical Center -
Cleveland Clinic Foundation -
Case Western Reserve University School of Medicine
Hospital
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John Muir Medical Center, Walnut Creek -
Ronald Reagan UCLA Medical Center -
Santa Monica-UCLA Medical Center and Orthopaedic Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1912922097 |
| Last Name Of The Provider | MATHERN |
| First Name Of The Provider | GARY |
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