Professor, Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine
Pathology
Dr. Fritz Parl, MD
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Dr. Fritz Parl practices Pathology. He went to New York Medical College - Metropolitan Hospital Center. Dr. Fritz Parl is also published. He has 90 publications published. The lastest publication: "Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer.'
Publications
- Implementation of a closed-loop reporting system for critical values and clinical communication in compliance with goals of the joint commission.
- A mathematical model for DNA damage and repair.
- A multistage association study identifies a breast cancer genetic locus at NCOA7.
- Estrogen metabolism and exposure in a genotypic-phenotypic model for breast cancer risk prediction.
- Neural factors in experimental degenerative arteriopathy.
- Mechanisms involved in the regulation of steroid receptor levels.
- Neural factors contribute to atherogenesis.
- Effect of electrical brain stimulation on erythrocyte membrane lipids.
- Uptake of triiodothyronine and thyroxine by isolated rabbit adipocytes.
- Neural factors in atherogenesis: experimental studies.
- Endothelial injury. Association with elevations of serum bile acid and cholesterol concentration in biliary-obstructed rats.
- Selective isolation of human breast carcinoma cells resistant to the growth-inhibitory effects of retinol.
- p53 mutations are confined to the comedo type ductal carcinoma in situ of the breast. Immunohistochemical and sequencing data.
- Ultrastructural changes of coronary artery endothelium associated with biliary obstruction in the rat.
- Relationship of small and large coronary artery disease to myocardial ischemia.
- Intracellular actions of gonadal steroids.
- Pathological and histomorphometric study of the effects of alcohol on the human duodenum.
- Estrogen receptor gene analysis in estrogen receptor-positive and receptor-negative primary breast cancer.
- Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females.
- Prognostic significance of estrogen receptor status in breast cancer in relation to tumor stage, axillary node metastasis, and histopathologic grading.
- Facilitation of granulocyte migration into bovine pulmonary artery intimal explants by intact viable endothelium.
- Comparison of histochemical and biochemical assays for estrogen receptor in human breast cancer cell lines.
- The histologic and biologic spectrum of tubular carcinoma of the breast.
- A retrospective cohort study of Histologic risk factors in breast cancer patients.
- The carcinoid syndrome: neuroendocrine and chemical considerations.
- The histopathological evaluation of human breast cancers in correlation with estrogen receptor values.
- Computer-assisted interpretive reporting with trend analysis of creatine kinase and lactate dehydrogenase isoenzyme determinations.
- Localization of human prealbumin in choroid plexus epithelium.
- Estrogen receptor determination in human breast cancer.
- Multiple mechanisms of estrogen receptor gene repression contribute to ER-negative breast cancer.
- Microsatellite instability and loss of heterozygosity in breast cancer.
- p53 gene mutations and steroid receptor status in breast cancer. Clinicopathologic correlations and prognostic assessment.
- Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells.
- Long-term risk of breast cancer in women with fibroadenoma.
- A 10-year analysis of "revenues," costs, staffing, and workload in an academic medical center clinical chemistry laboratory.
- Breast cancer risk associated with proliferative breast disease and atypical hyperplasia.
- High-mobility group (HMG) protein HMG-1 and TATA-binding protein-associated factor TAF(II)30 affect estrogen receptor-mediated transcriptional activation.
- Impact of managed care on the economics of laboratory operation in an academic medical center.
- Breast cancer and CYPIA1, GSTM1, and GSTT1 polymorphisms: evidence of a lack of association in Caucasians and African Americans.
- Mapping of ER gene CpG island methylation-specific polymerase chain reaction.
- Methylation of estrogen and progesterone receptor gene 5' CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors.
- Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer.
- Estrogen replacement therapy in women with a history of proliferative breast disease.
- Cytochrome P450 1B1 (CYP1B1) pharmacogenetics: association of polymorphisms with functional differences in estrogen hydroxylation activity.
- Aberrant methylation of the estrogen receptor and E-cadherin 5' CpG islands increases with malignant progression in human breast cancer.
- Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer.
- No elevation in long-term breast carcinoma risk for women with fibroadenomas that contain atypical hyperplasia.
- Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: comparison of wild-type and variant COMT isoforms.
- Metabolic gene polymorphism frequencies in control populations.
- Cerebrospinal fluid alpha-fetoprotein in germ cell neoplasms.
- Genomic DNA analysis of the estrogen receptor gene in breast cancer.
- Localization of transferrin and its receptor in ovarian follicular cells: morphologic studies in relation to follicular development.
- Prenatal diagnosis of sickle cell anemia. Hemoglobin electrophoresis versus DNA analysis.
- Influence of exogenous estrogens, proliferative breast disease, and other variables on breast cancer risk.
- Computer-assisted graphic display of serial cyclosporine determinations in blood with parallel creatinine concentrations.
- Discrepancies of the biochemical and immunohistochemical estrogen receptor assays in breast cancer.
- Automated enzymatic method for measuring oxalate in urine.
- Detection of estrogen receptor mRNA in human uterus.
- Late recurrence of surgically removed prolactinomas.
- An automated device for aseptically aspirating serum from blood collection tubes.
- Automated enzymatic measurement of lecithin, sphingomyelin, and phosphatidylglycerol in amniotic fluid.
- Neuroblastoma in adults. Pathologic findings and clinical outcome.
- Choroid plexus as a barrier to immunoglobulin delivery into cerebrospinal fluid.
- Analysis of the PvuII restriction fragment-length polymorphism and exon structure of the estrogen receptor gene in breast cancer and peripheral blood.
- Binding analysis of the estrogen receptor to its specific DNA target site in human breast cancer.
- Studies on the involvement of lysosomes in estrogen action, II. Seasonal variation in the sedimentation patterns of endometrial lysosomes from prepuberal pigs.
- Histologic and morphometric study of chronic gastritis in alcoholic patients.
- Methoxyestrogens exert feedback inhibition on cytochrome P450 1A1 and 1B1.
- Sequential action of phase I and II enzymes cytochrome p450 1B1 and glutathione S-transferase P1 in mammary estrogen metabolism.
- Increased prevalence of the HFE C282Y hemochromatosis allele in women with breast cancer.
- Association of homozygous wild-type glutathione S-transferase M1 genotype with increased breast cancer risk.
- Association of metabolic gene polymorphisms with tobacco consumption in healthy controls.
- Glutathione S-transferases M1, T1, and P1 and breast cancer: a pooled analysis.
- In vitro model of mammary estrogen metabolism: structural and kinetic differences between catechol estrogens 2- and 4-hydroxyestradiol.
- Breast cancer risk associated with estrogen receptor expression in epithelial hyperplasia lacking atypia and adjacent lobular units.
- Estrogen receptor genotypes and haplotypes associated with breast cancer risk.
- Immunohistochemical expression of estrogen receptor in enlarged lobular units with columnar alteration in benign breast biopsies: a nested case-control study.
- Cytochrome P450 1B1 and catechol-O-methyltransferase genetic polymorphisms and breast cancer risk in Chinese women: results from the shanghai breast cancer study and a...
- Glutathione S-transferase genotypes and cancer risk.
- Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women.
- Estrogens, enzyme variants, and breast cancer: a risk model.
- Meta- and pooled analyses of the cytochrome P-450 1B1 Val432Leu polymorphism and breast cancer: a HuGE-GSEC review.
- Calcium-phosphorus product and troponin-T values in renal failure.
- Cytochrome P450 1B1-mediated estrogen metabolism results in estrogen-deoxyribonucleoside adduct formation.
- Recombinant antibody piezoimmunosensors for the detection of cytochrome P450 1B1.
- Carcinogen-induced histone alteration in normal human mammary epithelial cells.
- Estrogen metabolism and breast cancer: a risk model.
- Estrogen exposure, metabolism, and enzyme variants in a model for breast cancer risk prediction.
- A need for true GSTM1 and GSTT1 genotyping.
Doctors Specialties
- Pathology
Accepted Insurances
- Amerigroup (Wellpoint)
- Humana
- Medicare MCR
- Tricare
- WellCare
Education
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New York Medical College - Metropolitan Hospital Center -
University of Gottingen Faculty of Medicine
Hospital
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Vanderbilt Hospital and Clinics
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